Teams at BigHat Biosciences

Perform automated and manual high-throughput DNA preparation, protein expression, and characterization. Operate liquid handlers and analytical instruments, optimize laboratory processes, support reagent manufacturing, document experiments, develop SOPs, and improve production workflows. Collaborate with multidisciplinary teams in a dynamic biotech environment while managing multiple projects and scheduled shifts.

Lead bench-based developability assessments for late-stage AI-designed biologic drug candidates. Design and execute dose-solution compatibility and stability studies, develop chromatography-based protein characterization methods, support formulation and stress testing, interpret biophysical and analytical data, manage CRO testing, and communicate findings and recommendations across the organization.

Develop generative and predictive machine learning models for antibody sequence, structure, and property design. Build multi-objective protein optimization and LLM-driven methods for lab-in-the-loop drug development, deploy models with engineering teams, and support therapeutic programs. Collaborate across machine learning, drug development, wet-lab science, automation, and data science teams to accelerate the creation of safer, more effective biologic therapies.