Top Durham, NC Biotech Startups (24)

Bioskryb is a venture-backed startup bringing new solutions for cellular heterogeneity, in both the research and clinical space studies, using a proprietary genome amplification system.

Isolere is re-imagining how complex biologics can be manufactured more efficiently. To achieve this, we have combined two phenomena highly evolved by nature -- specific affinity binding and liquid-liquid phase separation. Our team of passionate and talented scientists are working to bring an adeno-associated virus (AAV) manufacturing technology--IsoTag AAV--to market. IsoTag promises to address today's major AAV production bottlenecks. Our...

A Mosaic company. Our diverse portfolio of products is backed by science and used worldwide to enhance yields, improve nutrient use efficiency, disease defense, biocontrol and abiotic stress. We’re committed to developing new soil health solutions that will provide advanced crop nutrition to customers around the globe and continue to help the world grow the food it needs.

ABOUT BRIGHTSEED Brightseed is a world leader in biosciences and artificial intelligence that illuminates nature to restore human health. Through our Forager® A.I., Brightseed helps companies gain the deepest insight into bioactives and their innovation potential. Forager accelerates bioactive discovery and biological validation from years to months – and is rapidly revealing new connections between nature and humanity. Brightseed partners with...

ScitoVation provides clients with the science, technical expertise and technology to understand how chemical compounds and drugs affect human health. Known for partnership, flexibility and proven success, we help clients develop safer and more effective pharmaceuticals, food ingredients, agricultural chemicals, commodity chemicals, and consumer products. We are recognized as industry experts in cell-based and computational methods who answer profound questions...

Transforming lives through advancements in biomaterials.

As the industry’s best-in-class, complete real world evidence (RWE) solution, Target RWE is a distinctly collaborative enterprise that unifies real world data (RWD) sets and advanced RWE analytics in an integrated community, shifting the paradigm in healthcare for how decisions are made to improve lives. Target RWE sources unique, connected data sets across multiple therapeutic areas representing granular data from diverse...

StrideBio is a product-driven, fully integrated gene therapy company focused on creating and developing innovative genetic medicines with life-changing or curative potential for patients with devastating conditions, including monogenic rare disease and beyond. We leverage our proprietary structure-inspired adeno-associated virus (AAV) vector engineering platform to create unique and differentiated vectors that improve upon naturally occurring AAV serotypes to overcome current...

New reverse osmosis membranes are what the industry has been waiting for. Reverse osmosis has been proven to be the most efficient way to purify water. However, this process has also proven to be more expensive than what it could be. We will bring innovation to desalination by introducing these new membranes that will knock out biofouling and ultimately be...

Humacyte, Inc. (Nasdaq: HUMA) is developing a disruptive biotechnology platform to deliver universally implantable bioengineered human tissues and organs designed to improve the lives of patients and transform the practice of medicine. The Company develops and manufactures acellular tissues to treat a wide range of diseases, injuries and chronic conditions. Humacyte’s initial opportunity, a portfolio of human acellular vessels (HAVs),...

Aerami Therapeutics is developing a new generation of inhaled therapies for the treatment of severe respiratory and chronic diseases. Our platform is designed to overcome the limitations of injectable, oral, and other inhaled formulation technologies for managing severe respiratory and chronic diseases. Ultimately, our aim is to improve treatment efficacy and improve patient lives. To learn more, visit: https://aerami.com/

AgBiome discovers and develops innovative biological and trait products for crop protection.

Tavros Therapeutics is a precision oncology platform company leading the new frontier of targeted therapies exploiting tumors’ genetic vulnerabilities. The result is a drug discovery engine that can discover novel drug targets with a clear path forward to the clinic to get the right drugs to the right patients, faster.

Grant Engine is regularly identified as the leading platform for securing non-dilutive funding. We work directly with you to develop the right, best story to secure funding for your products. We write the grant with your essential inputs. As a team of scientists and entrepreneurs, Grant Engine understands what it takes to build a differentiated product to improve the standard of...

Avazyme, Inc. a contract research solution provider, offering field and laboratory testing, product development, and expert consulting services to the agriculture and food industries. Avazyme’s comprehensive services include food safety analyses for contaminants, pathogens, allergens, food quality and nutrition analysis, genetic trait testing, product safety, FDA Menu Labeling, pesticide residues, mycotoxin analysis, specialized studies for regulatory submission data packages, and...

Lindy Biosciences is a development-stage protein therapeutic formulations company. Our core technology, Microglassification™, produces spherical, dense, stable particles of a therapeutic protein. These protein particles are ideal for long-term storage, or for incorporation into drug delivery formulations such as suspensions(for high-concentration delivery of antibodies), encapsulation (for sustained/controlled release), or dry powder pulmonary delivery.​

The vast majority of human disease is governed by the epigenome, the subtle machinery that controls the volume of gene expression in cells. Tune Therapeutics is pioneering the creation of epi-therapeutic medicines with its powerful and precise epigenomic control platform, TEMPO. Unlike genome editing, TEMPO dials the volume of gene expression up or down towards healthy levels, without breaking or...

Codetta Bio™ is developing advanced multi-omic biomarker measurement tools supporting data-driven approaches to understanding the unique genetic, environmental, lifestyle, and clinical factors that contribute to individual health and wellness.

Altis has developed a patent-pending stem cell technology recreating the human intestinal epithelium for compound screening and microbiome research. The product is called RepliGut. It will allow drugs to be tested on an in vitro platform that more closely mimics native human biology. Our goal is to enable pharmaceutical companies to identify effective compounds earlier, before clinical trials; to reduce...

Ribometrix is a platform therapeutics company discovering small molecule drugs that target functional 3D RNA structures to treat human diseases. Our scientific offices are located in the newly renovated Biolabs Space in Durham, with offices in Chapel Hill and Boston.