Top Senior Level Software Engineer Jobs in Wilmington, NC

Reposted 19 Days AgoSaved
Remote
USA
190K-220K Annually
Senior level
190K-220K Annually
Senior level
Biotech
Lead software engineering efforts for the Proton platform, focusing on system design, mentorship, and innovative drug discovery projects. Collaborate with cross-disciplinary teams to enhance engineering processes and standards within a minimalist organizational structure.
Top Skills: AWSDjangoDockerKubernetesPostgresPython
Reposted 19 Days AgoSaved
In-Office or Remote
13 Locations
Senior level
Senior level
Other • Sales
Lead the backend architecture, mentoring engineers, and defining technical standards while building scalable systems for data processing and LLM integration.
Top Skills: AWSCi/CdDockerKubernetesLlm ApisOpenaiPostgresPythonTerraform
Reposted 19 Days AgoSaved
Remote or Hybrid
2 Locations
Senior level
Senior level
Hardware • Internet of Things • Energy • Industrial
Design, build, and optimize scalable cloud and web software with focus on infrastructure, performance, and hardware integration for IoT devices. Collaborate with hardware teams to ensure connectivity and high availability, implement new features, and improve system efficiency.
Top Skills: AWSIotJavaJavaScriptPythonReact
Reposted 19 Days AgoSaved
In-Office or Remote
7 Locations
75K-96K Annually
Senior level
75K-96K Annually
Senior level
Social Impact
The Senior Back-End Developer builds and maintains server-side operations for cloud solutions, collaborating with teams to deliver software, support users, and document features.
Top Skills: AWSDockerGoKubernetesPHP
Reposted 19 Days AgoSaved
Remote
2 Locations
150K-215K Annually
Senior level
150K-215K Annually
Senior level
Artificial Intelligence • Fintech
Lead frontend product experiences across web and mobile using React/React Native and TypeScript. Design conversational, AI-native financial planning interfaces, define frontend architecture and component systems, and contribute to AI layer, multi-model orchestration, reliability, and observability. Work cross-functionally across backend, infra, analytics, and product in a seed-stage, remote environment to ship fast, user-trusted experiences.
Top Skills: Agentic OrchestrationAnthropicCloudflareExpoHerouiLlmsOpenaiOpentofuPlanetscalePostgresReactReact NativeTailwindTanstack QueryTanstack RouterTerraformTypescriptUniwind
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Reposted 19 Days AgoSaved
Remote
US
150K-220K Annually
Senior level
150K-220K Annually
Senior level
Healthtech • Automation
The role involves building and debugging components across the stack, focusing on patient care coordination tools, while collaborating with AI technology.
Top Skills: Athena EmrBigQueryFastapiFastifyFhirGCPHl7LangfuseLanggraphNext.JsPostgresPrismaPythonReactTerraformTypescriptVertex Ai
Reposted 19 Days AgoSaved
Remote
United States
95K-177K Annually
Senior level
95K-177K Annually
Senior level
Gaming
Develop applications for game operations, build backend APIs, and frontend components using various technologies, collaborating with teams across the company.
Top Skills: AWSGitGoGCPKubernetesMongoDBNext.JsNode.jsPostgresPythonReactRedisSQLTerraformTypescript
Reposted 19 Days AgoSaved
Remote
US
Senior level
Senior level
Information Technology
Serve as technical lead for software development, testing, deployment support, release management, requirements analysis, defect resolution, and technical oversight for MIS. Lead development, testing, UAT, Section 508 compliance, performance/capacity testing, documentation, and modernization/migration efforts.
Top Skills: .Net FrameworkAsp.NetBusiness ObjectsC#Crystal ReportsHTMLIisObject-Oriented DesignSQL ServerUmlVisual StudioXML
Reposted 19 Days AgoSaved
Remote
3 Locations
Senior level
Senior level
Information Technology • Software • Database • Automation
Lead architecture and technical strategy across an infrastructure platform ecosystem. Drive hands-on architectural improvements to graph engine and backend services, reduce technical debt, establish standards, champion AI-first engineering practices, run architecture/code reviews and mentorship, and collaborate with product and leadership to ensure scalable, extensible systems.
Top Skills: Python
Reposted 19 Days AgoSaved
Remote
United States
Senior level
Senior level
Fintech • Software • Financial Services
The Senior Backend Engineer will lead client projects, build AI solutions, and develop technical standards while mentoring junior engineers.
Top Skills: AWSAzureDbtGCPGitJupyterLangchainMatplotlibMl FrameworksPandasPolarsPydantic AiPydata StackPythonPyTorchScikit-LearnSQLTensorFlow
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