Top Remote Machine Learning Jobs in San Diego, CA

Lead the machine learning strategy, design scalable ML systems, drive MLOps, mentor engineers, and comply with AI governance.

As a Senior Staff Machine Learning Engineer at Affirm, you will lead complex ML system design and implementation, mentor engineers, and drive innovative ML strategies for financial services.

As a Principal Software Engineer, you'll architect and code backend services and ML models, integrate them with Salesforce, and mentor junior engineers.

Lead and transform the Fraud Intelligence Team into a high-impact function by improving operating models, QA, tooling, and metrics; build entry-level talent programs; connect labeling to measurable fraud prevention outcomes; deliver actionable insights to Product, R&D, Analytics, and GTM; and leverage AI and automation to increase productivity and business impact.

You will tackle AI challenges, develop scalable software and collaborate with teams to enhance healthcare navigation using AI solutions.

Serve as second-in-command for Coinbase Derivatives' Market Regulation Department, leading day-to-day regulatory compliance, managing exams and audits, advising on CFTC Core Principles, reviewing surveillance escalations and enforcement actions, and coordinating cross-functional regulatory workstreams to ensure the DCM meets obligations and resolves findings timely.

Own product strategy and delivery for chat, voice, and proactive support surfaces to maximize automation rates and CSAT. Build AI-integrated capabilities with ML/LLM teams and vendors, partner with Engineering, CX Operations, Data Science, and Compliance on platforms (Amazon Connect, Sprinklr, Salesforce), drive build-vs-buy decisions, and execute cross-functional delivery to optimize customer and agent experiences.

Use advanced analytics and ML to design and monitor credit risk models, optimize underwriting and credit strategies, partner with Engineering/Product/Compliance, oversee portfolio performance and regulatory alignment, and lead cross-functional initiatives to balance growth, compliance, and risk mitigation.

As a Staff Machine Learning Engineer, you will design AI products on Edge devices, optimize ML model performance, and work with large-scale datasets, collaborating across teams to deliver impactful solutions.

As an ML Ops Infrastructure Engineer, you will design CI/CD pipelines for ML, maintain deployment systems, and implement monitoring while collaborating with research teams to ensure model quality and performance.

As a Systems Architect, you'll define and drive the infrastructure architecture for AI/ML workloads, design multi-cloud strategies, manage compute orchestration and storage systems, and lead capacity planning, while also collaborating with engineering leadership.

The engineer will build and operate AI/ML infrastructure, managing services on AWS and bare metal, using tools like Kubernetes and Terraform.

Lead development and evaluation of AI products for medical professionals using large-scale datasets. Create product and client-facing analytics, influence data team strategy, and collaborate with product managers, analysts, and engineers to execute data projects from ingestion through analysis to recommendations.

Manage a team of data scientists to develop fraud detection models, lead planning and collaboration with leadership, and communicate outcomes effectively while maintaining strong business intuition and technical leadership.

Design, build, and operate production ML decision systems to detect and prevent payment fraud, account takeover, identity abuse, merchant/marketplace risk, scams, and other adversarial activity. Own end-to-end production lifecycle: data contracts, low-latency inference, batch scoring, feature quality, deployment, monitoring, incident response, rollback, and feedback loops. Develop AI-assisted workflows and reusable decision capabilities while partnering with modelers, product, compliance, and operations.

Design, build, and operate production ML signal systems—ranking, retrieval, recommendations, propensity, and next-best-action—covering feature/candidate generation, serving, experimentation, monitoring, and feedback. Define signal contracts (freshness, provenance, confidence), evaluate long-term impact (trust, fairness, compliance), and partner across product, data, and risk teams to deliver reusable customer-intelligence capabilities.

Lead development and production of underwriting and credit decisioning models across Cash App Borrow and Afterpay. Own full modeling lifecycle: problem formulation, feature engineering, training, calibration, experimentation, deployment, monitoring, and iteration. Build decision frameworks, agentic engineering workflows, and collaborate with cross-functional partners to align model behavior with business and regulatory goals.

The Senior Staff Machine Learning Scientist will lead research initiatives in computer vision and multimodal understanding, develop novel models, and translate research into practical applications while mentoring team members.

Lead the Data + ML Platform team to design, build, and operate scalable data and MLOps infrastructure. Drive platform strategy, enable ML experimentation-to-production workflows (model registry, feature stores, drift monitoring, experiment tracking), modernize streaming and batch pipelines, and scale the team while partnering cross-functionally to deliver measurable outcomes.

As an AI Engineer, you'll work closely with customers to understand their needs, train and deploy models, and build scalable AI systems.

This role involves designing, deploying, and maintaining machine learning and AI models in production, managing ML pipelines, and ensuring system reliability and performance.

The AI Developer is responsible for designing and deploying AI solutions, including autonomous agents and predictive models, and integrating them into business operations.

The Machine Learning Engineer will develop editable visuals combining computer vision and machine learning, enabling chat-driven figure editing and leveraging biological understanding to produce accurate visuals.

The Senior Product Architect will design security products, collaborating with product management and engineering teams, focusing on architecture and functionality for high-level product features.

The Product Marketing Manager will execute product launches and support go-to-market initiatives, collaborating with cross-functional teams to develop and deliver messaging and enablement materials targeting both technical and business stakeholders.