Top Remote Software Engineer Jobs in Raleigh-Durham, NC

Senior backend engineer responsible for setting technical direction, designing scalable distributed systems, building customer-facing web applications, mentoring engineers, and applying machine learning to large-scale healthcare data. The role requires Java, Scala, or Rust expertise, cloud systems experience, technical design leadership, cross-functional collaboration, and adoption of agentic engineering practices.

Leads the design, development, and delivery of complex software systems. Drives architectural decisions and technical strategy, mentors engineers, conducts code reviews, partners with product stakeholders, and improves system performance, scalability, security, and compliance. Owns technical initiatives from design through delivery while maintaining high engineering standards.

Develop and support InterSystems IRIS and Caché applications for laboratory and healthcare interoperability. Responsibilities include designing ObjectScript classes and productions, building HL7 interfaces, developing APIs and data workflows, optimizing SQL and IRIS data structures, migrating Caché to IRIS, troubleshooting integrations, supporting deployments, and ensuring FDA and HIPAA compliance. The role also involves solution design, root-cause analysis, collaboration with stakeholders, mentoring, and limited onsite sessions.

Lead end-to-end Salesforce-centric architecture and integrations across cloud platforms (.NET, Azure, AWS). Design scalable, secure solutions, oversee data migrations, mentor engineers, and contribute hands-on development and operational troubleshooting.

Build responsive Bubble.io applications for startup clients, collaborate with product managers and designers, refine requirements, test tools and assumptions, communicate with clients weekly, and contribute reusable components and tutorials to the internal library. The role offers autonomy, client exposure, and opportunities to advance into technical leadership or product management.

Supports Microsoft Dynamics 365 CRM and Power Platform administration, development, automation, troubleshooting, and user support. Builds and maintains Power Apps, Power Automate workflows, Power BI reports, dashboards, dataflows, and Fabric Lakehouse structures. Assists with requirements gathering, testing, documentation, data quality, and process improvement while collaborating with business stakeholders and senior technology staff. This remote role includes limited travel and focuses on improving organizational efficiency, reporting, customer experience, and business applications.

Design, implement, and optimize gameplay mechanics and systems. Collaborate with designers, artists, and developers to troubleshoot and refine code, optimize performance across platforms, and maintain clean modular code while staying current with game technologies.

Develop and maintain PowerUp Sports’ software platform, build and release new features, integrate technologies, optimize PHP applications on Azure, manage SQL Server databases, participate in code reviews, mentor junior developers, and support scalable, reliable architecture.

Support software development across frontend, backend, web, and mobile applications. Responsibilities include developing with WordPress, React, Next.js, Flutter, and Java; testing and maintaining applications; participating in code reviews; collaborating with teammates; and staying current with software development technologies.

Lead the design, development, and operation of production-grade automation, agent frameworks, and CI/CD pipelines supporting documentation, localization, and language operations. Integrate platforms through REST APIs and MCPs, apply LLM capabilities responsibly, improve reliability and scalability, establish reusable standards, and mentor engineers. The role is fully remote in the US, with preferred Eastern or Central time zone availability.