VP, Head of R&D Clinical Creation Center

Posted Yesterday
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3 Locations
In-Office
274K-457K Annually
Expert/Leader
Artificial Intelligence • Healthtech • Machine Learning • Natural Language Processing • Biotech • Pharmaceutical
We’re in relentless pursuit of breakthroughs that change patients’ lives.
The Role
Leads Pfizer’s R&D Clinical Creation Center, owning digital, data, and AI capabilities across the clinical trial lifecycle. Establishes technology strategy, manages a significant budget, modernizes eClinical platforms, embeds AI and analytics into trial delivery, and shifts teams toward product-oriented Agile models. Partners with clinical, scientific, and R&D leaders while building a high-performing cross-functional organization and maintaining regulatory, quality, and compliance standards.
Summary Generated by Built In
About the Role
The R&D Clinical Creation Center sits at the intersection of technology and clinical execution, owning the digital, data, and AI capabilities that power the full clinical trial spectrum - from study planning and design through execution, monitoring, and delivery of clean, reportable data. This leader will serve as the single point of accountability in Digital for budget management and for delivery against prioritized R&D impact, defining and driving the strategy for how emerging technologies, including AI, are embedded into how Pfizer plans and runs clinical trials. They will partner closely with CD&O and the broader R&D organization to translate capability into measurable impact.
Key Responsibilities
  • Own end-to-end accountability for all digital, data, and AI enablers supporting the clinical trial lifecycle - study planning, design, startup, execution, monitoring, closeout, and reporting.
  • Serve as the single point of accountability in Digital for budget management and for delivery against prioritized R&D impact across the R&D Clinical Creation Center portfolio.
  • Define and execute a forward-looking technology strategy that incorporates AI and advanced analytics into clinical trial planning, optimization, and delivery.
  • Lead the R&D Clinical Creation Center team using product-oriented delivery models and Agile ways of working, shifting from project-based to product-based operating models where appropriate.
  • Partner with CD&O, R&D therapeutic areas, biostatistics, and translational medicine leadership to ensure technology investments are grounded in real operational and scientific need.
  • Evaluate, select, and integrate emerging platforms and tools (e.g., clinical data capture, eClinical systems) to modernize and simplify the trial technology environment for all consumers: Pfizer colleagues, clinical sites, patients, regulators, et al.
  • Build and develop a high-performing, cross-functional team spanning technology, data science, and clinical domain expertise.
  • Establish governance, prioritization, and delivery frameworks that balance innovation with regulatory, quality, and compliance requirements.
  • Serve as a thought partner to R&D leadership on the future of AI-enabled clinical development.

Required Qualifications
  • Bachelor's degree and 15+ years of experience in digital product delivery, with demonstrated success leading technology organizations through modern, product-oriented operating models.
  • 5+ years of experience in the clinical domain, including clinical operations, clinical development, or scientific/medical functions.
  • Proven track record applying Agile ways of working (Agile WoW) at scale, including experience shifting teams from traditional project delivery to product-centric models.
  • Direct experience applying AI/ML to study planning, trial optimization, and/or clinical delivery.
  • Strong track record partnering with senior clinical, scientific, and business stakeholders to translate strategy into delivered capability.
  • Experience leading through organizational change and ambiguity.
  • Demonstrated experience owning and managing a technology budget of significant scale, with accountability for delivery outcomes.

Preferred Qualifications
  • Experience with clinical data platforms (e.g., RedCap Cloud, Veeva, or comparable eClinical systems).
  • Background in pharmaceutical or biotech R&D technology environments.
  • Advanced degree in a relevant scientific, technical, or business discipline.

Last Date to Apply for Job: 10/9/2026
The annual base salary for this position ranges from $274,000.00 to $456,600.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 30.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.
Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email [email protected] . This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers .
Information & Business Tech

Skills Required

  • Bachelor’s degree
  • 15+ years of experience in digital product delivery
  • 5+ years of experience in clinical operations, clinical development, or scientific/medical functions
  • Experience applying Agile ways of working at scale and shifting teams from project delivery to product-centric models
  • Direct experience applying AI or machine learning to study planning, trial optimization, or clinical delivery
  • Experience partnering with senior clinical, scientific, and business stakeholders to translate strategy into delivered capabilities
  • Experience leading through organizational change and ambiguity
  • Experience owning and managing a significant technology budget with accountability for delivery outcomes
  • Experience with clinical data platforms such as REDCap Cloud, Veeva, or comparable eClinical systems
  • Background in pharmaceutical or biotech R&D technology environments
  • Advanced degree in a relevant scientific, technical, or business discipline
  • Permanent authorization to work in the United States

What the Team is Saying

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Esteban
Pfizer

Pfizer Compensation & Benefits Highlights

  • Healthcare Strength — Health coverage is described as comprehensive across medical, dental, vision, and mental‑health support, with strong plan options and provider networks. Feedback suggests these programs are a clear standout within the total rewards package.
  • Retirement Support — Retirement programs feature a 401(k) with company matching plus an additional company retirement contribution. Feedback suggests these elements are consistently highlighted as valuable components of overall compensation.
  • Leave & Time Off Breadth — Paid vacation, holidays, and sick time are often characterized as generous, with some locations offering the ability to purchase additional vacation days. Feedback suggests this breadth contributes meaningfully to work‑life balance.

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The Company
HQ: New York, NY
121,990 Employees
Year Founded: 1848

What We Do

Our purpose ensures that patients remain at the center of all we do. We live our purpose by sourcing the best science in the world; partnering with others in the healthcare system to improve access to our medicines; using digital technologies to enhance our drug discovery and development, as well as patient outcomes; and leading the conversation to advocate for pro-innovation/pro-patient policies.

Why Work With Us

We are the inventors, the problem solvers, the big thinkers — those who surmount any hurdle to deliver breakthrough medicines to the people who are counting on them the most.

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Pfizer Offices

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Employees engage in a combination of remote and on-site work.

Typical time on-site: 2.5 days a week
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