VP, Computational Sciences

Posted 5 Days Ago
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Boston, MA
Senior level
Biotech
The Role
The VP of Computational Sciences will lead the Computational Platform at Ampersand Biomedicines, driving technological advancements and strategic direction. Responsibilities include mentoring teams, implementing data management practices, and collaborating with scientific teams to analyze high-quality datasets for NGS and machine learning, contributing to innovation in drug development.
Summary Generated by Built In

Company Summary 

Ampersand Biomedicines is an innovative, privately held biotechnology company leading the way in developing programmed biologics that only act where they are needed in the body (www.Ampersand.bio).  Ampersand was founded in Flagship Pioneering’s venture creation engine, where companies such as Moderna Therapeutics (NASDAQ: MRNA) and Seres Therapeutics (NASDAQ: MCRB) were conceived and created.  With a strong emphasis on innovation, Ampersand cultivates a highly dynamic and entrepreneurial environment.  

Position Summary 

We are seeking a dynamic and passionate leader for the Computational Platform at Ampersand. Successful candidates bring a strong combination of scientific acumen, proven leadership and the ability to drive a platform vision forward while working in a highly collaborative environment. This role requires expertise related to machine learning, multi-omics data analysis & integration, database design, next-generation sequencing (NGS) data and a background with protein-based drug modalities. As the VP of the Computational Platform, you will lead and build a talented team, providing strategic direction and ensuring the successful execution of our computational platform vision. The ideal candidate must be independent, goal-oriented, have excellent communication skills, be motivated to learn new skills and work in a fast-paced entrepreneurial environment. 

Key Responsibilities 

  • Help define and implement strategic, operational and financial plans for the computational platform aligned with Ampersand’s goals of driving AND-Body therapeutics
  • Mentor, inspire, and build a high-performing computational team, promoting professional growth and development.
  • Lead efforts to implement and advance new technologies and analyses across the computational platform, working closely with the other scientific teams to generate and interpret high quality data sets for machine learning and platform development
  • Work closely with program heads to establish data infrastructure and analytical workflows
  • Work with computational and experimental scientists to establish data management practices and SOPs to improve efficiency
  • Communicate strategy and results to internal and external parties in verbal, written, and presentation formats, with clear data visualizations
  • Contribute meaningfully to building a world-class AND-Body platform at the forefront of scientific innovation 

Minimum Qualifications 

  • PhD in Computational Biology, Bioinformatics, Computer Science, or a related field 
  • Significant experience (8+ years) in computational biology or a related field with at least 4 years in a leadership role
  • Proven track record of successfully leading and building high-performing teams.
  • Extensive experience with machine learning, data science, integration and analysis of NGS data
  • Experience with NGS and bioinformatics tools
  • Experience with cloud environments such as AWS
  • Ability to develop and execute strategic plans, driving the Platform vision with key stakeholders.
  • Excellent communication, interpersonal, and organizational skills.
  • Ability to thrive in a fast-paced, dynamic environment and manage multiple priorities simultaneously. 

Preferred Qualification:  

  • Experience with antibody binder design and multi-omics data analysis  
     

What We Will Offer you: 

  • Comprehensive, competitive healthcare and dental coverage through Blue Cross Blue Shield, vision coverage through VSP, family leave, paid time off, 401k retirement plan, disability and life insurance, and fully covered parking/commuter benefits.
  • A dynamic early-stage work environment and highly interdisciplinary, talented, and collaborative team.
  • Participation in an unprecedented opportunity to significantly impact the quality of life of patients by developing a targeted approach to delivering therapeutic molecules.
  • Professional growth opportunities through mentoring, training, immersion in cross-functional projects, and opportunities to learn and try new things. 

About Flagship

Flagship Pioneering is a biotechnology company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value. Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.  Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

Flagship Pioneering is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto



Top Skills

Machine Learning
The Company
HQ: Cambridge, MA
475 Employees
On-site Workplace
Year Founded: 2000

What We Do

Flagship Pioneering conceives, creates, resources, and develops first-in-category life sciences companies to transform human health and sustainability.

Since its launch in 2000, the firm has applied a unique, hypothesis-driven innovation process to originate and foster more than 100 scientific ventures, resulting in over $30 billion in aggregate value. To date, Flagship is backed by >$3 billion of aggregate capital commitments, of which over $1.5 billion has been deployed toward the founding and growth of its pioneering companies alongside >$10 billion of follow-on investments from other institutions.

The current Flagship ecosystem includes Denali Therapeutics (NASDAQ: DNLI), Evelo Biosciences (NASDAQ: EVLO), Moderna Therapeutics (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), Seres Therapeutics (NASDAQ: MCRB), and Syros Pharmaceuticals (NASDAQ: SYRS).

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