Chai Discovery builds frontier AI models to design molecules and transform how new cures are found. We are a craft-obsessed team setting out to re-architect drug discovery and save lives.
Chai was founded by leading researchers in the space and proven silicon valley operators, who previously co-invented protein language modeling, built state-of-the-art folding algorithms, and sold AI adopted by top-10 pharma companies. We have raised $230m from tier one investors, including OpenAI, Thrive, General Catalyst, Oak HC/FT, and Dimension. Our thesis is that small, elite teams out-iterate rivals.
Why Now?Deal volume and complexity continue to grow, especially post-launch of Chai-2. With many transactions in motion, Chai Discovery is seeking a VP, Business Development to serve as the operational engine behind high-stakes pharma partnership deals. This person will play a key role in shaping innovative transaction structures and novel IP frameworks for a revolutionary AI drug discovery platform.
About the roleThe VP, Business Development will partner with our founders to advance and secure strategic partnerships essential for Chai’s growth. As a strong operator with a growth-mindset, exceptional project management and problem-solving skills, and a passion for driving transactions to completion, this executive will play a key role in the evolution of the business at a critical juncture.
Key ResponsibilitiesCultivate, manage, and push each deal forward. Lead negotiation of business points and translate the company’s business model and pricing strategy into clear, actionable deal structures. Serve as the operational lead managing all timelines, workflows, and cross-functional threads required to keep deals moving forward.
Participate in the creation and management of “deal maps”, outlining each partnership’s path, key decision points, gatekeepers, and anticipated interpersonal, political, and business dynamics.
Own the full contracting workflow, including drafting cycles, redlines, internal reviews, and coordination with external counsel, while maintaining momentum across all legal components of each deal, ensuring strategic partnerships progress smoothly from initial discussion through close.
Help define and maintain the IP strategy supporting partnerships.
Oversee contracts beyond partnerships, including CRO agreements and data-generation partners.
Execution-focused deal operator with legal grounding (JD preferred) and experience drafting, reviewing, and driving complex contracts forward.
Background in biotech/pharma, or alternatively in startups/technology companies handling complex enterprise deals involving sensitive IP, software, AI models, or regulated data.
Experience in a law firm supporting biotech, pharma, or regulated technology clients is also highly relevant.
Demonstrated ability to run multi-step deals end-to-end, managing many simultaneous conversations, legal processes, and cross-functional threads.
Detail-oriented and intellectually sharp, with strong judgment and the ability to spot risks, implications, and structural issues early.
Hungry, thoughtful, and highly reliable, someone who founders and executives can trust with day-to-day deal mechanics.
Track record of operating effectively in lean, founder-led, high-growth environments.
Highly motivated by impact, responsibility, and the opportunity to shape a high-growth company’s commercial trajectory.
A smart and thoughtful force multiplier, with strong judgment and the ability to reason clearly across legal, commercial, and operational dimensions.
Detail-oriented operator who takes pride in precision, thoroughness, and getting the mechanics right.
Low-ego collaborator who builds trust quickly with founders, executives, partners, and cross-functional teams.
Proactive and resourceful, able to anticipate needs, identify gaps, and implement solutions without being asked.
Curious and growth-oriented, excited to learn the nuances of AI-driven discovery and partnership structures.
Comfortable with ambiguity, shifting priorities, and wearing multiple hats in a lean team. Can clearly articulate complex ideas across disciplines to internal and external stakeholders.
Chai Discovery is based in San Francisco, CA.
We offerFrontier technology: work on the technologies that promises to fundamentally change how new therapeutics are created.
World-class people: work with world-renowned leaders in the AI x Biology ecosystem.
Velocity and ownership: we move incredibly fast and liberally distribute ownership, which means continuous learning and career growth opportunities are guaranteed.
Strong culture and mission: we foster a supportive culture that is mission-driven and high-energy.
Highly competitive compensation: we attract the best talent and compensate them accordingly.
What We Do
Building frontier artificial intelligence to predict and reprogram the interactions between biochemical molecules.







