Vice President, Data Science and Machine Learning

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South San Francisco, CA, USA
In-Office
Healthtech • Biotech
The Role

Vice President, Data Science and Machine Learning

Position Overview

As the Vice President of Data Science and Machine Learning (DSML), you will lead Genentech’s enterprise-wide strategy to harness data science and machine learning (ML) in transforming how we discover insights, personalize customer experiences, and accelerate our mission to improve patient outcomes. Reporting to the SVP, Head of Data, Digital, and Analytics (DDA), you will shape and scale high-impact data science and ML capabilities that are deeply embedded in the decision-making, operations, and digital workflows across Commercial, Medical, and Government Affairs (CMG).

This role combines strategic leadership with deep technical stewardship. You will guide a world-class team of data scientists, ML engineers, and AI product managers while building strong partnerships within DDA and across CMG, Informatics, and Legal to ensure DSML innovation is responsible, compliant, and scalable. Your leadership will be central to positioning Genentech at the forefront of healthcare AI transformation.

Key Responsibilities:

  • Define and execute a bold, enterprise-level data science and machine learning strategy aligned to Genentech’s mission and CMG goals.

  • Serve as the strategic thought partner to CMG leadership to ensure data science is a core enabler of business growth, operational efficiency, and patient impact.

  • Partner with DDA functional teams to develop a cross-functional product roadmap for data science, ML, predictive AI, genAI, agentic AI. 

  • Partner with the Informatics (IX) team to develop a scalable, secure, and compliant ML/AI platform ecosystem — from experimentation to production deployment.

  • Set the scientific and technical direction for the Data Science and ML function; lead the development of cutting-edge methodologies in areas such as predictive and prescriptive modeling, time-series and causal inference, graph ML and network science, natural language processing and LLM fine-tuning, generative and agentic AI systems, real-world evidence analytics and treatment simulation.

  • Lead development of reusable AI/ML components and enterprise models across CMG domains such as HCP/patient engagement, forecasting, field force optimization, and real-world data analytics.

  • Oversee architecture and technical strategy for end-to-end ML workflows, including data pipelines, feature stores, model training/validation/deployment, and performance monitoring.

  • Partner with IX to ensure adoption of best-in-class MLOps practices to scale reproducible, automated, and compliant data science, ML, and AI development across use cases.

  • Define and track success metrics (e.g., adoption, performance, ROI) for data science and machine learning products and platforms.

  • Partner with Digital Experience and Informatics teams to integrate data science and AI into content generation, omnichannel engagement, CRM, and digital operations. Drive adoption of generative and agentic AI solutions to enhance speed, creativity, and personalization in business workflows.

  • Contribute to enterprise AI governance policies and ethical frameworks to ensure responsible AI development and use.

  • Lead strategic partnerships with academia, technology providers, and consortia to ensure Genentech remains at the forefront of AI innovation.

  • Champion a culture of experimentation, agile execution, and continuous learning.

  • Inspire, lead, and develop a high-performing team of data science experts. Foster a culture of respect, inclusion, growth mindset, and accountability. 

  • Attract, develop, and retain top-tier talent in data science, ML engineering, and AI product management.; nurture the next generation of data science leaders.

Qualifications

  • Master's degree in Data Science, Computer Science, Engineering, Statistics, or related field required; Ph.D.strongly preferred.

  • 15+ years of progressive leadership experience in data science, AI/ML within healthcare, life sciences, or highly regulated industries.

  • 10+ years of experience leading large teams, both in direct reporting as well as cross-functional groups.

  • Deep expertise in data science, machine learning, statistical modeling, and AI platform technologies.

  • Proven track record of driving AI/ML innovation from concept to scaled deployment, especially in complex matrixed organizations.

  • Extensive experience with modern ML frameworks (e.g., PyTorch, TensorFlow), MLOps tools, and cloud platforms (e.g., AWS, GCP, Azure).

  • Deep understanding of generative and agentic AI technologies

  • Experience leading/working with product management team in an agile environment

  • Strong business acumen with the ability to align data science initiatives to strategic and operational goals.

  • Experience building and governing ethical AI frameworks and navigating compliance in highly regulated environments.

  • Advanced knowledge of workflow tools, automation systems, and compliance frameworks is a plus.

  • Ability to lead and develop high-performing teams, fostering a culture of innovation and continuous learning.

  • Strong leadership and team management abilities, with experience in coaching, developing, and inspiring talent.

  • Excellent communication and stakeholder management skills, with demonstrated success in facilitating cross-functional collaboration.

Location

  • This position is based in South San Francisco, CA

  • Relocation assistance is available.

The expected salary range for this position based on the primary location of South San Francisco, CA is 293,700 - 540,000. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.  A discretionary annual bonus may be available based on individual and Company performance.  This position also qualifies for the benefits detailed at the link provided below.

 Benefits

*LI-TW1

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

Genentech Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Genentech and has not been reviewed or approved by Genentech.

  • Healthcare Strength Health coverage is described as comprehensive across medical, dental, vision, mental health, and prescriptions, supported by HSAs/FSAs and broad wellness resources. On‑site fitness and health centers, mental‑health clinicians, and specialized programs like fully covered preventive cancer screenings and menopause support deepen the offering.
  • Retirement Support Retirement benefits feature a 401(k) with up to a 4% company match plus an additional annual 6% company contribution to eligible pay. Additional financial protections such as life and accident insurance complement salary, bonuses, and stock options.
  • Leave & Time Off Breadth Time away includes about 20 paid vacation days, paid holidays, personal days, and a year‑end shutdown. A paid six‑week sabbatical every six years notably expands long‑term time‑off flexibility.

Genentech Insights

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The Company
HQ: South San Francisco, CA
20,069 Employees
Year Founded: 1976

What We Do

Considered the founder of the industry, Genentech, now a member of the Roche Group, has been delivering on the promise of biotechnology for more than 40 years. Genentech is a biotechnology company dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and life-threatening diseases. Our transformational discoveries include the first targeted antibody for cancer and the first medicine for primary progressive multiple sclerosis. We're passionate about finding solutions for people facing the world's most difficult-to-treat conditions. That is why we use cutting-edge science to create and deliver innovative medicines around the globe. To us, science is personal. Making a difference in the lives of millions starts when you make a change in yours.

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