Reporting to the Director, Technical Sales & Field Application Scientists, the Technical Project Manager will lead all aspects of project management, coordination, and implementation relative to the NGS Services Lab and related businesses of Twist Bioscience. This role owns execution from customer intake through delivery, driving scalability, process optimization, and cross-functional alignment across a technically complex, high-throughput service environment.
The role manages the full range of communications required to facilitate each project, including customers, sales & field application support, Twist customer service, Twist legal, and the Twist product management group — encompassing non-disclosure agreements, customer quotes, purchase orders, and statements of work.
What You'll Be DoingProject Leadership for the NGS Service and Applications LabIntake, Scoping & Quoting- Serve as the technical and operational lead during project intake, translating customer needs into clearly scoped, executable NGS service programs (DNA, RNA, methylation, long-read)
- Own project definition and intake, including:
- Customer objectives — translate complex customer goals into optimized sequencing strategies and workflows
- Scope, assumptions, and constraints
- Workflow design and feasibility
- Cost, timelines, dependencies, and deliverables
- Success criteria aligned to customer outcomes
- Partner with Sales and FAS to shape opportunities early, including:
- Defining the right assay or sequencing approach
- Identifying risks, tradeoffs, and alternative strategies
- Setting realistic expectations with customers
- Prepare and distribute quotes for NGS service projects; maintain an up-to-date, accessible database of issued quotations, NDAs, purchase orders, and statements of work
- Own end-to-end project coordination following intake through final delivery, ensuring continuity between scoping, lab execution, and data delivery
- Serve as the central coordination hub across all functions, including: Lab Operations, Bioinformatics, Customer-facing teams (Sales / FAS), and the Customers
- Drive regular project syncs with the lab manager (daily/weekly) to track progress vs. timeline, identify risks, and ensure alignment across teams
- Serve as the primary point of contact for project updates post-intake
- Establish and maintain clear communication cadence, including: status updates, timeline changes, data delivery, and invoicing
- Manage customer expectations proactively, especially around: turnaround time (TAT), data quality, and scope changes or technical challenges
- Maintain real-time visibility of all active projects, including a transparent, accessible work-in-progress (WIP) list, in coordination with the lab team
- Maintain accurate, timely records across all systems to enable up-to-date reporting on quotes issued, orders placed, orders in progress, and orders shipped
- Follow applicable regulatory and quality requirements, including ISO 13485, for the service lab
- Provide technical and project leadership to coordinators and cross-functional partners supporting the NGS service lab
- Identify and drive process optimization and scalability improvements across the intake-to-delivery lifecycle
- Support ad hoc strategic projects as required
- PhD in Biology, Genetics, Genomics, Molecular Biology, Chemistry, or a related Life Science field
- 5+ years of relevant experience utilizing Next Generation Sequencing (NGS) technologies, including project or program management experience, with demonstrated experience in a customer-facing role
- Expert understanding of NGS workflows (DNA, RNA, methylation, long-read) and the customer workflows the associated service offerings address
- Proven track record managing complex, technical projects from intake through delivery that meet customer expectations
- Proven ability to influence and lead cross-functional teams, and to work effectively with customers, internal operations, and sales teams
- Outstanding leadership, teamwork, and communication skills
- Hands-on, high-energy, positive attitude with a can-do approach that gets it done
- Highly motivated and results-oriented, with the ability to work under pressure and a strong sense of urgency
- Strong organizational skills and excellent problem-solving abilities
- Must be able to work outside of regular work hours / a flexible schedule as needed
Skills Required
- Bachelor’s or master’s degree in Molecular Biology, Biochemistry, Chemistry, or a related field; an associate degree with relevant experience may be considered
- Hands-on experience with molecular biology techniques, including PCR, DNA purification, DNA quantification, and library preparation
- Experience working in a laboratory environment
- Strong attention to detail and documentation practices
- Ability to manage multiple tasks and prioritize effectively in a fast-paced environment
- Strong organizational, planning, and problem-solving skills
- Excellent interpersonal and communication skills with a collaborative mindset
- Self-motivated with a commitment to delivering high-quality results
- 3–5 years of experience in molecular biology, NGS workflows, or a related field
- Direct experience with NGS platforms such as Illumina, PacBio, Element, or ONT
- Experience with NGS library preparation and target enrichment workflows
- Experience with DNA, RNA, and methylation NGS assays
- Familiarity with BioAnalyzer, TapeStation, Qubit fluorometry, and Nanodrop spectrophotometry
What We Do
Twist Bioscience is a synthetic biology company based in South San Francisco, California. The company has developed a proprietary silicon-based manufacturing process for the production of synthetic DNA. Twist Bioscience serves Life Science researchers who are changing the world for the better. Coming from diverse fields of medicine, agriculture, industrial chemicals and data storage, scientists use our synthetic genes, oligo pools, and NGS target enrichment to better lives and improve the sustainability of the planet. Twist Bioscience is uniquely positioned to help accelerate these efforts by providing precision at a scale that is otherwise unavailable. Our technology overcomes inefficiencies and enables cost-effective, rapid, precise, high-throughput DNA synthesis and sequencing. We offer both the quality and quantity researchers need now to rapidly realize opportunities ahead.
