Technical Program Manager

Reposted 2 Days Ago
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San Jose, CA
In-Office
Mid level
Biotech • Pharmaceutical
The Role
Oversee pre-clinical program development, coordinating research activities across departments, managing risks and stakeholder communications, while driving program management best practices.
Summary Generated by Built In

About Oxford Biotherapeutics:

Oxford BioTherapeutics (OBT) is a clinical-stage biotechnology company developing antibody therapeutics for the treatment of cancer. You will play an integral role in the pre-clinical development of novel immuno-oncology therapeutics. Our OGAP® platform is the world's largest, cancer specific, membrane protein library, directly measuring plasma membrane protein expression in patient tumors. OGAP is used to identify novel, highly tumor specific antigens for novel first-in-class ADC, Bispecific T-cell Engager (BITE®) and Chimeric Antigen Receptor (CAR) targets.  Our lead asset, OBT076, is an Antibody Drug Conjugate (ADC) in Phase 1b clinical development.  Our clinical and pre-clinical pipeline of novel biologics is balanced between internal programs, focused on ADCs and checkpoint regulators, and externally partnered programs with key innovators in oncology such as Boehringer Ingelheim, Zymeworks and Roche.


Purpose of the Role

This role’s key focus, as part of a Program Management Office, is to oversee the development of various preclinical programs from initial discovery to IND enabling activities in a timely and organized manner. This will entail coordinating research activities from multiple internal departments that jointly synergize into a final product.


Roles and Responsibilities:

  • Oversee program development internally, aligning with scientific team leaders and internal / external stakeholders. Develop and implement program management methodologies, ensuring alignment with overall corporate strategy and balancing requirements and resources across all active programs
  • Drive best practices in program and portfolio management, and establish a consistent approach across the organization and takes ownership of the management of risk, opportunities, and interdependencies across programs
  • Facilitate the resolution of issues across programs, ensuring alternative solutions are explored, assist with resolving obstacles, and escalate issues where necessary
  • Ensure adequate support to assist other teams, importantly including the science teams, with developing project plans, assessing resource needs, etc.
  • Review and enhance a strategic portfolio review process, including integrated plans and metrics as appropriate
  • Serve as the point of contact for program reporting, proactively ensuring visibility of key issues, risks, and opportunities to enable decision making on a timely basis
  • Maintains and manages excellent relationships with existing alliance partners to ensure their satisfaction
  • Meet and regularly communicate with science, program and alliance management colleagues in collaborator organizations
  • Organize meetings that facilitate program progression and take appropriate meeting notes for proper documentation of action items and next steps
  • Establish and maintain strategic relationships with vendors to ensure cost-effective procurement, quality compliance, and timely delivery of goods and services.
  • Be the point of contact for external and internal stakeholders from beginning to end of target validation process

Please note the roles and responsibilities for the position include but are not limited to the above



Desired Knowledge, Experience, and Skills:

  • Bachelor's degree in scientific discipline, Master's or PhD degree preferred
  • Experience managing and leading multiple complex projects/programs from early-stage research to clinical development, defining strategy, and portfolio management
  • Strong understanding of drug development processes strongly preferred, including clinical and non-clinical study design and execution, etc.
  • Program management experience in Biotechnology, specifically oncology space is a plus
  • Experienced in effectively working with senior team members in cross-functional teams.
  • Deep understanding and experience in program and portfolio management, including and understanding of PM tools, standards and methodologies.
  • Strong planning capabilities, including budgeting and forecasting
  • Experienced leader of teams, with outstanding coaching and mentoring skills, people focused on achieving collective goals
  • Point of contact for internal and external stakeholders with proven track record in resolving issues, building solutions through engagement of others, and driving decision making in cross-functional teams.
  • Empowering leader who engages others to take ownership of projects and drive decisions forward.
  • Outstanding communication skills including presentation, verbal and written communication
  • Excellent interpersonal skills including influencing, negotiating, facilitation, and listening.
  • Ability to work in a fast paced, team environment, meet deadlines, and prioritize and balance work from multiple individuals
  • Independently motivated, detail oriented and good problem-solving ability
  • Systematic organization skills
  • At least 3 years' experience in project budgeting and financial analysis
  • Track record of working with business units to deliver on contractual profitability

Behaviors

  • Proactive team player
  • Adaptability, resiliency, and commitment
  • Customer and stakeholder awareness
  • Optimistic problem solving
  • Strong relationship building

 One of our top priorities is to maintain the health and wellbeing of our employees and their families. To achieve this goal, we offer comprehensive benefits.


Benefits Offered:

  • Medical, dental and vision insurance
  • The full premium amount for our employees and their dependents is covered by IGM
  • FSA – Healthcare and dependent care (Flexible Spending Account)
  • STD, LTD, Basic Life and AD&D Insurance, Supplemental Life and AD&D Insurance
  • 401(k) Plan
  • 120 hours of Paid Time Off
  • 5 sick days per year
  • 11 holidays
  • Employee Referral Bonus Program
  • Annual training budget for professional development
  • Annual bonus program
  • New hire stock options

Equal Opportunities Statement

OBT is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status, and veteran status. All qualified applicants will receive consideration for employment. One of our top priorities is to maintain the health and wellbeing of our employees and their families. To achieve this goal, we offer comprehensive benefits.

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The Company
HQ: Oxford
55 Employees
Year Founded: 2004

What We Do

Oxford BioTherapeutics (OBT) is a clinical stage oncology company based in Oxford, UK; San Jose, CA and Morristown, NJ, USA, with a pipeline of first-in-class immuno-oncology (IO) and antibody-drug conjugate (ADC) based therapies designed to fulfil major unmet patient needs in cancer therapeutics.

Our lead asset, OBT076, is an Antibody Drug Conjugate (ADC) in Phase 1b clinical development. OBT076's dual mechanism of action allows it to act as a 'primer' to re-engage the patient's immune system while at the same time targeting cancer cells directly.

OBT’s proprietary OGAP® target discovery platform is based on one of the world’s largest proprietary cancer membrane proteomic databases, with data on over 5,000 cancer cell proteins providing unique, highly qualified oncology targets, of which three programs are in clinical development in the USA and Europe.

The company’s pipeline and development capabilities have been validated through multiple strategic partnerships, including with Boehringer Ingelheim, ImmunoGen and Kite Pharma as well as other world leaders in antibody development (such as Amgen, WuXi, Medarex (BMS), Alere (Abbott)).

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