Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead’s RNAi-based therapeutics leverage this natural pathway of gene silencing.
Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.
Arrowhead’s corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.
The Position
The Innovation Engineering Intern will support Arrowhead Pharmaceuticals’ efforts to advance next-generation manufacturing technologies by contributing to the design and development of innovative engineering systems. This internship offers hands-on experience working with mechanical design, prototyping, and system integration in a collaborative research and development environment. The intern will work alongside engineers and scientists to help explore new approaches to manufacturing and gain exposure to modern engineering tools and technologies.
This is an 11-week Summer Internship Program paying $21.00 per hour and requires full-time, onsite work five days per week at the designated location.
Responsibilities
- Support the design and development of a small-scale engineering system used for research and development activities.
- Work hands-on to translate engineering concepts into physical components or assemblies.
- Create and update design drawings and models using CAD software.
- Assist with fabrication and assembly of system components using a mix of custom and commercially available parts.
- Support development and testing of control strategies or system logic.
- Contribute to testing, iteration, and refinement of system designs.
- Collaborate with engineers and cross-functional partners to document designs, processes, and learnings.
- Assist with basic data analysis or modeling related to system performance, as applicable.
Requirements
- Currently enrolled student at an accredited university or college, majoring in Mechanical Engineering or a related field.
- 1 year of CAD experience.
- 1 years experience programming in Python.
- Strong problem-solving and analytical skills.
- Excellent organizational skills and attention to detail.
- Demonstrated aptitude and enthusiasm for learning new technical skills
- Proficiency in Microsoft Office applications.
Preferred
- Experience with 3D printing, CAM, and CNC machining.
- Experience creating mechanisms and mechanical assemblies.
- Exposure to controls systems or automation engineering.
- Experience with Raspberry Pi programming or embedded systems.
- Interest in continuous manufacturing, Pharma 4.0, and GMP system design.
Arrowhead provides competitive salaries and an excellent benefit package.
All applicants must have authorization to work in the US for a company.
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What We Do
Arrowhead Pharmaceuticals is a clinical stage, Nasdaq listed (ticker ARWR) company developing medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, our therapies trigger the RNA interference mechanism to induce rapid, deep and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Our RNAi-based therapeutics are at the leading edge of genetic-based therapy with the potential to bring life changing treatments for patients.
Our Targeted RNAi Molecule (TRiMTM) platform utilizes ligand-mediated delivery and is designed to enable tissue-specific targeting while being structurally simple. The TRiM platform builds on more than a decade of work on actively targeted drug delivery and offers several advantages including simplified manufacturing and reduced costs; multiple routes of administration; and potential for improved safety.
Our employees are nimble, science-driven, and innovative professionals. A career at Arrowhead offers the opportunity to collaborate with top notch scientists to rapidly discover and develop RNAi-based therapeutics to add to our growing pipeline.
Research and development activities are located in Madison, WI. Our R&D group includes fully-integrated capabilities for chemistry, biology, and toxicology. Madison is an exciting and sophisticated city that includes state government, the flagship campus of the University of Wisconsin, and major research organizations.
Our HQ, clinical and regulatory operations are located in Pasadena, CA. Just north of Los Angeles and resting in the foothills of the San Gabriel Mountains, Pasadena is known for its natural scenic beauty, vibrant cultural and academic environment and rich architectural setting.
