Staff Software Engineer

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Woodlands
In-Office
Healthtech • Biotech
The Role
What if the work you did every day could impact the lives of people you know? Or all of humanity?

At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.

Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.

Staff Software Engineer:
Join Illumina’s Multi-Omics Software team within R&D and play a lead role in the design and development of cutting-edge next generation data and analysis platforms to unlock the power of the genome – to transform healthcare and beyond.

As a Staff Software Engineer, you will be part of an innovative, dynamic, and adaptive organization supporting new and on-market cloud-based products that streamline the generation, analysis, aggregation, and extraction of insights from data.

Responsibilities:

  • Design, implement, and optimize the performance of large-scale distributed systems with security and compliance in mind.

  • Build SaaS based commercial products to process and analyze terabytes of data

  • Own all aspects of implementation for features from design to development, deployment to production, and support and maintenance.

  • Writing clean, performant, and well-tested code

  • Identify and resolve performance bottlenecks, security vulnerabilities, and other operational issues in the cloud environment

  • Participate in code reviews and contribute to the continuous improvement of development processes

All listed tasks and responsibilities are deemed as essential functions to this position; however, business conditions may require reasonable accommodations for additional tasks and responsibilities.

Key Qualifications:

  • Bachelor’s or master’s degree in Computer Science or equivalent

  • Minimum of 8 years of experience designing, implementing, and supporting highly scalable applications

  • Excellent Java development and debugging skills

  • Deep understanding of data architecture, system design, and scalability challenges

  • Proficient in building highly scalable services based on REST

  • Experience with front end technologies and/or front-end frameworks.

  • Knowledge of web libraries and frameworks such as Angular, React, Underscore

  • Proficient in various data stores: SQL, NoSQL, and/or key-value store

  • Experience with Cloud (AWS/Azure) based commercial systems. 

  • Experience with production-quality services, deployment, monitoring, and reliability.

  • Experience with numerous aspects of DevOps, including source control, CI/CD, Kubernetes and containerized deployment.

  • Demonstrated willingness to teach others and learn new technologies.

All listed requirements are deemed as essential functions to this position; however, business conditions may require reasonable accommodations for additional tasks and responsibilities.

Nice to Have:

  • Experience with next-generation sequencing data analysis (DNA, RNA, or multi-omics analysis.

  • Experience with data warehouse technologies (e.g., Iceberg, snowflake).


We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact [email protected]. To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf. The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants. This role is not eligible for visa sponsorship.

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The Company
HQ: San Diego, CA
7,400 Employees
Year Founded: 1998

What We Do

Illumina is an innovative technology and revolutionary assays aiming the analyze genetic variation and function.

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