Staff Software Engineer (AI Backend Services)

Posted Yesterday
36 Locations
In-Office or Remote
Senior level
Artificial Intelligence • Healthtech • Machine Learning • Natural Language Processing • Biotech • Pharmaceutical
We’re in relentless pursuit of breakthroughs that change patients’ lives.
The Role
Provides technical leadership for Python-based AI backend platforms supporting LLM integrations, generative AI pipelines, and agent orchestration. Architects scalable AWS systems using FastAPI, Lambda, and EKS; establishes observability and engineering standards; drives performance, security, and reliability improvements; mentors engineers; and influences organization-wide technical strategy, platform capabilities, and best practices.
Summary Generated by Built In
ROLE DESCRIPTION
The AI Backend Python Engineer (Staff) will provide technical leadership and define the architecture for backend systems that power the next generation of generative AI applications and large language model
(LLM) integrations. This role focuses on driving strategic technical direction, designing platform-level
solutions using Python, FastAPI, and AWS, and influencing engineering practices across the organization.
KEY RESPONSIBILITIES
  • Define technical strategy and architecture for Python-based AI backend platforms (on FastAPI) that support LLM integration, generative AI pipelines, and AI agent orchestration
  • Architect scalable, reliable, and secure systems on AWS infrastructure (Lambda, EKS) that serve as the foundation for multiple teams
  • Drive technical decisions that impact organization-wide engineering practices and platform capabilities
  • Design and champion AI system observability using LangChain, Langfuse, and litellm
  • Establish engineering standards for monitoring, logging, observability, and operational excellence across AI backend services
  • Lead cross-functional initiatives to optimize performance, security, and scalability of large-scale AI applications
  • Mentor and technically guide engineers at all levels, elevating team capabilities through code reviews, architecture reviews, and technical leadership
  • Identify technical debt, performance bottlenecks, and architectural limitations; drive long-term solutions
  • Collaborate with engineering leadership, product, and other stakeholders to align technical strategy with business objectives
  • Influence technology choices, design patterns, and best practices across the AI Software & Operations department
  • Represent the team in organization-wide technical discussions and drive adoption of innovative solutions

BASIC QUALIFICATIONS
  • 7+ years of professional software engineering experience with extensive backend and distributed systems expertise
  • Deep expert-level proficiency in Python for building large-scale production systems
  • Comprehensive understanding of LLMs, generative AI architectures, and AI infrastructure (LangChain, litellm, Langfuse, OpenAI/Anthropic APIs)
  • Proven track record of architecting and delivering complex, scalable platforms on AWS
  • Expert knowledge of microservices architecture, distributed systems design, and event-driven architectures
  • Demonstrated experience with containerization, orchestration (Docker/Kubernetes), and cloud-native patterns
  • Strong history of technical leadership, mentoring engineers, and driving organizational impact
  • Bachelor's or Master's degree in Computer Science, Engineering, or related field, or equivalent practical experience
  • Excellent strategic thinking and ability to balance short-term delivery with long-term architectural vision

PREFERRED QUALIFICATIONS
  • Extensive experience designing and building platform-level infrastructure for AI/ML workloads at scale
  • Deep expertise in FastAPI, asynchronous Python, and high-performance backend systems
  • Proven track record of architecting event-driven and real-time systems for AI applications
  • Experience influencing engineering culture, establishing best practices, and driving technical standards
  • Strong background in MLOps, model deployment strategies, and AI system reliability
  • Expertise with infrastructure-as-code, CI/CD automation, and platform engineering
  • Experience working with product and business stakeholders to translate requirements into technical strategy
  • History of leading cross-functional technical initiatives with measurable organizational impact
  • Published technical work, open-source contributions, or recognized expertise in AI backend systems
  • Exceptional communication and influence skills across all levels of the organization

Work location assignment : Remote
This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.
Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.
Égalité des chances & Emploi
Nous croyons que des équipes diversifiées et inclusives sont essentielles à la réussite d'une entreprise. En tant qu'employeur, Pfizer s'engage à valoriser la diversité et l'inclusion sous toutes ses formes. Cette diversité se reflète également à travers les patients et les communautés que nous servons. Ensemble, continuons à bâtir une culture qui encourage, soutient et responsabilise nos employés.
Handicap & Inclusion
Notre mission est de libérer le potentiel de nos collaborateurs et nous sommes fiers d'être un employeur inclusif pour les personnes handicapées, garantissant ainsi l'égalité des chances en matière d'emploi pour tous les candidats. Nous vous encourageons à donner le meilleur de vous-même en sachant que nous apporterons tous les ajustements raisonnables pour soutenir votre candidature et votre carrière future. Votre expérience avec Pfizer commence ici !
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email [email protected]. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
Pour mieux comprendre les usages autorisés et interdits de l'intelligence artificielle tout au long du processus de recrutement, nous vous invitons à consulter nos bonnes pratiques dédiées à l'utilisation de l'IA par les candidats sur Pfizer Careers .
Information & Business Tech

Skills Required

  • 7+ years of professional software engineering experience with extensive backend and distributed systems expertise
  • Expert proficiency in Python for large-scale production systems
  • Understanding of LLMs, generative AI architectures, and AI infrastructure
  • Experience with LangChain, litellm, Langfuse, and OpenAI or Anthropic APIs
  • Experience architecting scalable platforms on AWS
  • Expertise in microservices, distributed systems, and event-driven architectures
  • Experience with Docker, Kubernetes, containerization, orchestration, and cloud-native patterns
  • Technical leadership, mentoring, and organization-wide engineering impact
  • Bachelor’s or Master’s degree in Computer Science, Engineering, or a related field, or equivalent practical experience
  • Strategic thinking and ability to balance short-term delivery with long-term architecture
  • Experience designing platform infrastructure for AI/ML workloads at scale
  • Expertise in FastAPI, asynchronous Python, and high-performance backend systems
  • Experience architecting event-driven and real-time AI systems
  • Experience establishing engineering best practices and technical standards
  • Background in MLOps, model deployment, and AI system reliability
  • Expertise with infrastructure as code, CI/CD automation, and platform engineering
  • Experience translating product and business requirements into technical strategy
  • Experience leading cross-functional technical initiatives with measurable organizational impact
  • Published technical work, open-source contributions, or recognized AI backend expertise
  • Exceptional communication and influence skills

What the Team is Saying

Daniel
Anna
Esteban
Pfizer

Pfizer Compensation & Benefits Highlights

  • Healthcare Strength — Health coverage is described as comprehensive, spanning medical, dental, vision, and robust mental‑health benefits, with eligible Pfizer medications available at no cost in U.S. plans. Family‑building support and transgender‑inclusive care are explicitly included, alongside wellbeing resources such as a reimbursement wallet and telehealth options.
  • Retirement Support — Retirement programs feature a 401(k) with company matching plus an additional Retirement Savings Contribution, complemented by company‑subsidized life, short‑term disability, and long‑term disability insurance. Materials also reference subsidized retiree medical coverage for eligible groups.
  • Leave & Time Off Breadth — Paid vacation, holidays, personal days, and paid parental and caregiver leave are consistently highlighted in current U.S. summaries and job postings. Options like buying extra vacation days and transition‑back support strengthen the time‑off offering.

Pfizer Insights

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The Company
HQ: New York, NY
121,990 Employees
Year Founded: 1848

What We Do

Our purpose ensures that patients remain at the center of all we do. We live our purpose by sourcing the best science in the world; partnering with others in the healthcare system to improve access to our medicines; using digital technologies to enhance our drug discovery and development, as well as patient outcomes; and leading the conversation to advocate for pro-innovation/pro-patient policies.

Why Work With Us

We are the inventors, the problem solvers, the big thinkers — those who surmount any hurdle to deliver breakthrough medicines to the people who are counting on them the most.

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Pfizer Offices

Hybrid Workspace

Employees engage in a combination of remote and on-site work.

Typical time on-site: 2.5 days a week
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