Many structural heart patients suffer from heart failure with limited options. Our Implantable Heart Failure Management (IHFM) team, part of the AI, Product and Platforms organization, is at the forefront of addressing these unmet patient needs through pioneering technology that enables early, targeted therapeutic intervention. Our innovative solutions are not just transforming patient care but also creating a unique and exciting environment for our team members. It is our driving force to help patients live longer and healthier lives. Join us and be part of our inspiring journey.
At Edwards Lifesciences, the Implantable Heart Failure Management (IHFM) AI, Product and Platforms organization designs and builds the software and data products that clinicians and patients depend on. As a Staff Data Scientist, you design the modeling and evaluation approaches that others build on for a problem class, set validation strategy, and raise the modeling rigor of the teams around you, while remaining deeply hands-on.
Based in Irvine, CA, you'll join a high-impact medtech innovation hub in the heart of Orange County, collaborating in person with cross-functional teams to shape patient-focused technology.
How you'll make an impactApproach design. Design the modeling and evaluation approaches others build on for a problem class, for example, medical imaging segmentation or multimodal patient-state modeling, and build the reference implementations yourself.
Advanced paradigms. Bring advanced paradigms to bear where they fit, including self-supervised and contrastive learning, multi-task learning, and cross-modal fusion.
Validation strategy. Set offline validation, calibration, and clinical performance evaluation strategy, including subgroup and fairness analysis, with Medical Affairs and Clinical Science.
Reusable practice. Establish reusable modeling patterns, evaluation harnesses, and documentation practices that meet regulatory submission expectations.
Efficiency & scale. Apply label-efficient methods (active, semi-supervised, weak supervision) and efficient training at scale (distributed training with Ray or PyTorch).
Research evaluation. Lead evaluation of emerging AI/ML for health research and decide what to adopt for IHFM problems.
Technical leadership. Mentor senior and mid-level data scientists and shape the research to productization handoff with AI/ML Engineers (Applied).
Model performance, optimization & process enablement. Guide implementation of processes and tools to develop, analyze, and improve model performance and data accuracy; apply predictive modeling and algorithms to datasets to optimize outcomes (e.g., clinical trial experience) and ensure models remain current.
Stakeholder partnership, testing & reporting. Partner with internal and external stakeholders to plan implementation, testing, training, and monitoring of machine learning models; conduct ad hoc analyses (e.g., effectiveness metrics) and present results and insights to leadership.
Data governance, sourcing & enablement. Drive processing of structured and unstructured data with data stewards, including data governance practices; identify and integrate diverse data sources to enhance solutions in collaboration with business stakeholders.
Bachelor's in Computer Science, Engineering, Biostatistics or Scientific field plus 6 years of experience including either industry or industry / education -or- Master's plus 5 years -or- PhD plus 2 years.
Relocation is not provided for this role. Only candidates within a 50-mile radius of Irvine, California will be considered.
Deep domain expertise in cardiac, hemodynamic, imaging, or physiological modeling.
Recognized depth across multiple paradigms and architecture families, including self-supervised and multimodal approaches.
Depth in one or more data modalities (physiological modeling, medical imaging, or multimodal fusion) and in calibration and uncertainty quantification.
The ability to set modeling and validation standards that others follow, and to represent modeling decisions to clinical and regulatory partners.
Fluency across the modeling stack (for example, PyTorch, PyTorch Lightning, and experiment tracking) sufficient to set team practice.
Advanced generative or graph methods (diffusion models, graph neural networks), or federated learning methodology.
Demonstrated technical leadership and mentorship.
Performance engineering for training (C++, CUDA, JAX, or DeepSpeed).
A history of shaping clinical validation strategy and regulatory submissions for models.
Recognized research contributions in AI/ML for health.
Active learning or weak supervision to reduce clinical labeling cost.
Aligning our overall business objectives with performance, we offer competitive salaries, performance-based incentives, and a wide variety of benefits programs to address the diverse individual needs of our employees and their families.
For California (CA), the base pay range for this position is $126,000 to $178,000 (highly experienced).
The pay for the successful candidate will depend on various factors (e.g., qualifications, education, prior experience). Applications will be accepted while this position is posted on our Careers website.
Edwards is an Equal Opportunity/Affirmative Action employer including protected Veterans and individuals with disabilities.
COVID Vaccination Requirement
Edwards is committed to protecting our vulnerable patients and the healthcare providers who are treating them. As such, all patient-facing and in-hospital positions require COVID-19 vaccination. If hired into a covered role, as a condition of employment, you will be required to submit proof that you have been vaccinated for COVID-19, unless you request and are granted a medical or religious accommodation for exemption from the vaccination requirement. This vaccination requirement does not apply in locations where it is prohibited by law to impose vaccination.
Skills Required
- Bachelor's in Computer Science, Engineering, Biostatistics, or scientific field plus 6 years experience OR Master's plus 5 years OR PhD plus 2 years
- Must reside within a 50-mile radius of Irvine, California; relocation not provided
- Deep domain expertise in cardiac, hemodynamic, imaging, or physiological modeling
- Recognized depth across self-supervised, multimodal, and other advanced paradigms
- Experience in physiological modeling, medical imaging, multimodal fusion, and calibration/uncertainty quantification
- Ability to set modeling and validation standards and represent decisions to clinical and regulatory partners
- Fluency across modeling stack (e.g., PyTorch, PyTorch Lightning, experiment tracking)
- Experience with advanced generative or graph methods (diffusion models, GNNs) or federated learning
- Demonstrated technical leadership, mentorship, and shaping research-to-product handoff
- Performance engineering experience for training (C++, CUDA, JAX, or DeepSpeed)
- History of shaping clinical validation strategy and regulatory submissions for models
- Recognized research contributions in AI/ML for health and experience with active learning or weak supervision
Edwards Lifesciences Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Edwards Lifesciences and has not been reviewed or approved by Edwards Lifesciences.
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Retirement Support — Retirement programs include a 401(k) match complemented by a separate profit‑sharing contribution. These elements add meaningful long‑term value to total compensation.
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Equity Value & Accessibility — An employee stock purchase plan with a discount and look‑back feature, alongside stock awards for eligible roles, provides notable upside. Program expansions indicate continued accessibility.
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Leave & Time Off Breadth — Time‑off policies include generous PTO, company holidays, and a year‑end holiday shutdown. These offerings enhance work‑life support when available at the site.
Edwards Lifesciences Insights
What We Do
Edwards Lifesciences (NYSE: EW), is the global leader in patient-focused medical innovations for structural heart disease, as well as critical care and surgical monitoring. We thrive on discovery and expanding the boundaries of medical technology, serving patients in 100+ countries, with the help of our employees in areas including Clinical Affairs, Quality Engineering, Research & Development, Regulatory Affairs, Sales & Marketing, corporate functions and more. Our roots date back to 1958 when Miles Lowell Edwards, a retired engineer with a background in hydraulics and fuel pump operations, set out to build the first artificial heart. Edwards believed the heart could be mechanized and was encouraged by Dr. Albert Starr to focus on developing an artificial heart valve. After just two years, the first Starr-Edwards mitral valve was developed and successfully placed in a patient. This innovation spawned Edwards Laboratories. Miles’ fascination with healing the heart and helping patients with heart disease stemmed from his own experience with rheumatic fever as a teenager and continues to fuel our patient-first culture today. Today, we are as passionate about providing innovative solutions for people fighting cardiovascular disease as we have ever been. It's our Credo. It takes integrity, collaboration, innovation, and focus. We are leaders in the design and manufacture of tissue replacement heart valves and repair products as well as advanced hemodynamic monitoring. We partner with physicians to innovate products designed to help patients live longer, healthier, and more productive lives. Our work is both rewarding and a privilege. The importance of what we do defines our approach. We work together to create an environment where ideas can flourish and we provide our people with the resources, expertise and support to bring those ideas to life. For our legal terms and trademarks, please visit: https://www.edwards.com/legal/legal-terms







