Position Overview：
The Scientist, Upstream Process Development & MSAT Department. reports to the Senior Manager, Upstream Viral Vector Process Development & MSAT Department. This role is ideally suited for a dynamic, bench-focused individual to support and lead the translation of research processes to GMP-compliant manufacturing. The successful candidate will develop, scale-up, and evaluate the technology transfer of viral vector processes in a fast-paced biotechnology environment.
This position offers an excellent opportunity to develop and expand technical expertise in viral vector manufacturing while contributing to life-changing gene and cell therapies. The role combines hands-on laboratory work with strategic process development and cross-functional collaboration.
- Conduct hands-on experimental work in the development of upstream unit operations (cell culture, transfection, and harvest/clarification) for viral vector (AAV, LVV) manufacturing process.
- Design, execute, and analyze cell culture experiments using Design of Experiments (DOE) principles and report data summary packages.
- Collaborate with internal/external partnerships to evaluate and implement new bioprocessing technologies and strategies.
- Develop and optimize process parameters to improve yield, quality, and consistency of viral vector production with guidance.
- Independently follow detailed and comprehensive project timelines.
- Support/drive the start up of AAV/LVV lab operations including, but not limited to: Draft, review, and approval of Standard Operating Procedures (SOPs), Implementation of Lean 6 sigma/5s best practices, and streamlining material flow.
- Present updates to project or cross functional teams on process development and manufacturing support activities.
- Read and understand scientific literature in gene and cell therapy, use the knowledge to generate ideas and contribute to process design and development.
- Perform other duties as assigned based on business needs
Preferred Qualifications:
- Bachelor’s degree with 5-7 years, or Master’s Degree with 3-7 years, or Ph.D. degree with 0-3 years’ experience in Biology, Biochemistry, Chemical Engineering or equivalent with particular experience in gene and cell therapy product design.
- Experience with AAV and/or lentiviral vector production systems.
- Strong understanding of process scale-up, cGMP manufacturing technology transfer, and manufacturing support.
- Prior experience with cGMP manufacturing environment.
- Familiarization with analytical methods for viral vector characterization (qPCR, ELISA, HPLC).
- Familiarization of regulatory requirements for gene therapy products (FDA, EMA).
- Excellent organizational and project management abilities.
- Strong analytical and problem-solving skills with attention to detail.
- Strong interpersonal, verbal, and written communication skills.
Compensation: The salary range, dependent upon experience level, is $80,000 - $110,000 annually.
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GenScript USA Inc/ProBio Inc. is a proud equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is the Company's policy to ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protected by law.
GenScript USA Inc./ProBio Inc. maintains a drug-free workplace.
Please note: Genscript USA Inc./ProBio Inc. will only contact candidates through verified application sources. GenScript/Probio does not request personal information from candidates through individual email or any other platform.
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What We Do
Founded in 2002 and listed on the Hong Kong Stock Exchange in 2015, GenScript has an established global presence across Greater China, North America, the EU, and Asia Pacific. Today, over 300,000 customers from over 160 countries and regions worldwide have used GenScript’s premier, convenient, and reliable products and services. GenScript currently has over 5,000 employees globally, 33% holding master’s and/or Ph.D. degrees. In addition, GenScript has a number of leading commercial technologies developed in the fields of synthetic biology, immunotherapy, antibody design, chemical synthesis, and bioinformatics, including more than 100 patents and over 270 patent applications. As of June 2022, GenScript's products and services have been cited by 74,700 scientific papers worldwide. GenScript is committed to striving toward its vision of being the most reliable biotech company in the world to make humans and nature healthier through biotechnology.
