We are currently seeking a motivated Senior Principal Scientist to lead our AAV production team within Regeneron Genetic Medicines (RGM). You will oversee a talented team dedicated to supporting early-stage research for Regeneron’s gene therapy portfolio and technology development through production and purification of research-grade AAV.
As a Senior Principal Scientist, a typical day might include:
Directly supervise and manage Regeneron’s AAV Research Vector core, setting priorities and goals, facilitating cross-functional collaboration, forecasting demand, developing talent, and interfacing between RGM leadership, requestors, and team members.
Identify new strategies, instruments, and technologies to improve process yield, turnaround time, efficiency, consistency, and quality.
Collaborating with other Regeneron cores, technology centers, and therapeutic areas.
Contributing to departmental, cross-functional, senior leadership, and external meetings by providing expertise and communicating timelines, expectations, and vision
Working closely with RGM teams to enable the next generation of gene therapies
Providing technical support and assisting teams within the lab
Overseeing lab activities and implementation of new technologies and processes
Coordinating production teams to maximize effectiveness and streamline workflows
This might be the right role for you if you:
Are passionate about genetic medicines and supporting gene therapy development
Find yourself at home being close to the bench, but want additional leadership responsibilities
Enjoy problem solving and adapting to new technologies and challenges
Want to provide meaningful contributions to the development of an organizational culture that supports growth and development of its people and capabilities to drive forward the RGM pipeline
Are excited to mentor and develop team members, providing growth opportunities, fostering a collaborative environment, and engaging the team with the impact of their work
In order to be considered for this role, you must have at least a Ph.D. and 8-10+ years or a BS/MS and 15+ years of relevant experience in either Chemical Engineering, Biochemical Engineering, Molecular Biology, Gene Therapy or related field. We need someone with a strong foundational understanding of AAV-based gene therapies, protein and/or virus purification, chromatography, process development, and analytical techniques. Must have experience with managing a team (5+ direct reports) and directing the growth and development of our processes and talent. Experience working within or managing a core function or support group is preferred.
Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits, which often include (depending on location) health and wellness programs, fitness centers, equity awards, annual bonuses, and paid time off for eligible employees at all levels!
Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business.
For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location.
Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc.
Salary Range (annually)
Regeneron Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Regeneron and has not been reviewed or approved by Regeneron.
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Healthcare Strength — Medical, dental, and vision coverage is positioned as comprehensive, with Regeneron prescription drugs covered at 100% for those enrolled in the medical plan. Mental health support is also emphasized through EAP access and tools like Talkspace and the Journey app.
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Equity Value & Accessibility — Stock grants are described as available to all employees, strengthening the overall total-rewards package beyond base pay. Long-term incentives and stock-related rewards are repeatedly framed as meaningful components of compensation.
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Parental & Family Support — Paid parental leave is paired with fertility/adoption assistance and childcare-related support such as discounts and nanny services. Additional family-oriented resources extend to elder care, pet care, and education support like college coaching and tutoring.
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