Sr Director, Cyber Defense

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Chortiatis, GRC
Hybrid
Artificial Intelligence • Healthtech • Machine Learning • Natural Language Processing • Biotech • Pharmaceutical
We’re in relentless pursuit of breakthroughs that change patients’ lives.
The Role
ROLE SUMMARY
Our Cyber Defense team is the frontline of Pfizer's cybersecurity operations, responsible for detecting, investigating, and responding to threats that could impact the confidentiality, integrity, and availability of our systems and data. This team leads critical functions including Security Operations Center (SOC) monitoring, incident response, digital forensics, penetration testing, threat intelligence, host security, platform support, and security automation.
This leader will oversee enterprise-wide efforts in vulnerability management, threat intelligence, red teaming, SOC operations, incident response, insider risk, and secure network and cloud architecture. The ideal candidate will bring deep expertise in cyber operations, threat management, and security architecture, with a proven track record of driving large-scale, cross-functional cybersecurity programs. This role requires strong leadership, operational rigor, and the ability to translate technical risk into business-aligned strategies.
ROLE RESPONSIBILITIES
  • Define and execute a comprehensive strategy for the Cyber Security Posture Management, Network Security, Cloud Security, and Cyber Defense programs aligned with Pfizer's cybersecurity vision and business priorities.
  • Develop and manage budgets, ensuring alignment with organizational goals and effective allocation of resources. Monitor expenditures, forecast future budget needs and identify opportunities for cost optimization.
  • Serve as a key advisor to the CISO and senior leadership on threat trends, operational readiness, and incident response posture.
  • Lead the transformation of legacy cybersecurity systems and drive the implementation of modern security practices across the organization.
  • Oversee the global cyber defense program, inclusive of the 24x7 SOC, ensuring proactive threat detection, effective monitoring, alert triage, and coordinated incident response.
  • Direct the strategy and execution of Pfizer's cloud security program, ensuring robust controls across identity and access management, encryption, monitoring, and compliance.
  • Lead a proactive vulnerability management program, including scanning, prioritization, remediation, and executive reporting.
  • Partner with IT and business units to ensure timely resolution of critical vulnerabilities and alignment with enterprise risk tolerance.
  • Drive the strategy and implementation of network security controls, including segmentation, firewalls, intrusion detection/prevention, and secure remote access.
  • Ensure continuous monitoring and protection of Pfizer's global network infrastructure against emerging threats.
  • Lead and mentor high-performing teams across Cyber Posture Management, Network Security, Cloud Security, and Cyber Defense.

BASIC QUALIFICATIONS
  • Bachelor's degree in Cybersecurity, Computer Science, Information Systems, or related field.
  • 12 - 15+ years of experience in cybersecurity, with at least 8 years in leadership roles overseeing enterprise-wide cyber operations.
  • Proven expertise in multiple cybersecurity domains, including vulnerability management, threat intelligence, SOC operations, incident response, insider risk network security, and cloud security.
  • Strong understanding of security architecture and technologies such as firewalls, IDS/IPS, WAF, DDoS mitigation, SIEM, SOAR, and cloud-native security tools.
  • Professional certifications such as CISSP, GIAC (e.g., GCIA, GCIH), CISM, or equivalent.
  • Demonstrated ability to translate technical risk into business-aligned strategies and communicate effectively with executive stakeholders.
  • Deep familiarity with threat modeling frameworks and adversary simulation methodologies (e.g., MITRE ATT&CK, red/purple teaming).

PREFERRED QUALIFICATIONS
  • Extensive understanding of the Crowdstrike suite, including its capabilities for SIEM, EDR and threat intelligence.
  • Experience with Wiz for cloud security management, including configuration, monitoring, and reporting.
  • Experience with Zscaler for secure network access, including implementation, configuration, and performance optimization.
  • Experience leading modernization initiatives and transforming legacy cybersecurity systems.
  • Demonstrated experience negotiating multi-million dollar contracts with vendors and strategic partners.
  • Experience working abroad and leading global cybersecurity initiatives across multiple regions.

OTHER INFO
  • Periodic international and domestic travel may be required (less than 5%).
  • Work Location Assignment: Must be able to work in the assigned office 2-3 days per week, or as needed by the business.
  • This role is NOT remote.

Purpose
Breakthroughs that change patients' lives... At Pfizer we are a patient centric company, guided by our four values: courage, joy, equity and excellence. Our breakthrough culture lends itself to our dedication to transforming millions of lives.
Digital Transformation Strategy
One bold way we are achieving our purpose is through our company wide digital transformation strategy. We are leading the way in adopting new data, modelling and automated solutions to further digitize and accelerate drug discovery and development with the aim of enhancing health outcomes and the patient experience.
Flexibility
We aim to create a trusting, flexible workplace culture which encourages employees to achieve work life harmony, attracts talent and enables everyone to be their best working self. Let's start the conversation!
Equal Employment Opportunity
We believe that a diverse and inclusive workforce is crucial to building a successful business. As an employer, Pfizer is committed to celebrating this, in all its forms - allowing for us to be as diverse as the patients and communities we serve. Together, we continue to build a culture that encourages, supports and empowers our employees.
Disability Inclusion
Our mission is unleashing the power of all our people and we are proud to be a disability inclusive employer, ensuring equal employment opportunities for all candidates. We encourage you to put your best self forward with the knowledge and trust that we will make any reasonable adjustments to support your application and future career. Your journey with Pfizer starts here!
Information & Business Tech

What the Team is Saying

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Pfizer Compensation & Benefits Highlights

  • Parental & Family Support U.S. materials describe up to 26 weeks of parental leave (including up to 12 paid non‑medical weeks), with phased return‑to‑work plus fertility, adoption, and surrogacy financial support, backup care, lactation support, and caregiver leave. These offerings indicate depth in family‑building benefits and day‑to‑day caregiver resources.
  • Healthcare Strength Core programs commonly include medical, prescription drug, dental, vision, mental‑health/EAP resources, disability insurance, preventive health programs, and free or reduced‑cost vaccinations. Voluntary Benefit Extras and wellness resources broaden coverage and access.
  • Retirement Support Career pages and postings note a 401(k) with company matching plus an additional company retirement savings contribution in some plans. Company materials also reference financial‑planning education and colleague‑directed retirement funds.

Pfizer Insights

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The Company
HQ: New York, NY
121,990 Employees
Year Founded: 1848

What We Do

Our purpose ensures that patients remain at the center of all we do. We live our purpose by sourcing the best science in the world; partnering with others in the healthcare system to improve access to our medicines; using digital technologies to enhance our drug discovery and development, as well as patient outcomes; and leading the conversation to advocate for pro-innovation/pro-patient policies.

Why Work With Us

We are the inventors, the problem solvers, the big thinkers — those who surmount any hurdle to deliver breakthrough medicines to the people who are counting on them the most.

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