Summary
As Sr. Director, Business Finance, you will serve as the finance business partner to Innovation & Technology and Lab Operations SVPs and their orgs— two of GeneDx's most strategically important functions. These orgs are responsible for R&D, Product Management, IT, and overall COGS and Capex investments. You will design, build and maintain the financial infrastructure these teams need: the operating rhythms, forecasting models, decision frameworks, and dashboards that turn data into decisions. And then you will use that infrastructure to co-own financial outcomes with executive leaders who are ready and committed to a higher level of financial partnership.
In addition to this, you and your team will serve as Finance Business Partner to all the corporate functions (Legal, HR, Finance, and Medical Affairs) helping them manage opex spend to budget and in making sound finance decisions related to scaling and all investments.
You will lead a small, talented team — and over time, you will design the structure needed to deliver on the financial and business objectives of the functions you serve.
If you've spent your career operating inside a well-built FP&A function and you're ready to be the one who builds it — this is your role.
Job Responsibilities
- Full FP&A responsibility for Innovation & Technology and Lab Operations: annual planning, forecasting, and in-year financial management
- Design and implement a monthly financial operating rhythm that drives accountability and proactive decision-making with both SVPs
- Lead weekly, monthly, and quarterly business reviews — own the financial narrative, not just the numbers
- Prepare and partner on board-level financial decks presented by the SVPs — ensuring clarity, accuracy, and strategic coherence
- Identify and prioritize cost optimization opportunities and resource investment decisions in partnership with SVP leaders
- Co-own SIOP process with supply chain
- Define & build the financial infrastructure from the ground up: models, templates, dashboards, and decision frameworks
People Manager
- Yes
- Lead, coach, and develop a growing finance team — starting with an Associate Director and Finance Manager, with the autonomy to design the right structure over time
Education, Experience, and Skills
- 12+ years of progressive finance experience, with significant FP&A business partnership at the Director level or above
- Demonstrated experience building financial operating infrastructure — forecasting models, planning cycles, business review cadences — not inheriting them
- Proven track record of holding senior business leaders accountable to financial performance through structured operating rhythms
- Elite financial storytelling and executive presence. Translating complexity into clarity and you're credible in a board room
- Player-coach leadership style — you design the approach, develop your team to execute, and engage at the right level of detail
- A track record of driving decisions and business outcomes through finance and not just producing high-quality deliverables
Preferred
- Experience in life sciences, diagnostics, biotech, or healthcare
- Exposure to technology or lab/operations financial models
- Experience supporting functions through periods of rapid scaling or transformation
#LI-REMOTE
At GeneDx, we're driven by urgency and purpose: helping patients get diagnosed earlier. Our mission, to empower everyone to live their healthiest life through genomics, drives our team to make a tangible impact each day – and shapes our culture where high standards, strong teamwork, and meaningful ownership are the norm. We act with intention, support one another, and deliver work we're proud to put our names on.
Here’s what you can expect day to day:
1. Play like a champion (step up, redefine what’s possible, own it)
We bring energy, focus, and a bias for action. We step up, take initiative, and deliver on our commitments – with quality, speed, and care.
We push past the obvious. We challenge assumptions, raise the bar, and make thoughtful, decisive calls — choosing progress over perfection.
We stay curious, ask questions, and share direct feedback with respect. We adapt quickly and keep learning through collaboration and continuous improvement.
If you’re motivated by meaningful work, a fast-moving environment, and teammates who care deeply about outcomes, you’ll thrive at GeneDx.
We welcome everyone regardless of their background. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, gender, gender identity, sexual orientation, protected veteran status, disability, age, and other characteristics protected by law.
GeneDx is a place where people from all backgrounds can make an impact.
All privacy policy information can be found here.
Skills Required
- 12+ years of progressive finance experience
- Significant FP&A business partnership experience at Director level or above
- Experience building financial operating infrastructure, including forecasting models, planning cycles, and business review cadences
- Proven ability to hold senior business leaders accountable for financial performance through structured operating rhythms
- Strong financial storytelling and executive presence, including credibility in board-level settings
- Player-coach leadership style with experience designing approaches and developing teams
- Track record of driving decisions and business outcomes through finance
- Experience in life sciences, diagnostics, biotech, or healthcare
- Exposure to technology or laboratory and operations financial models
- Experience supporting functions through rapid scaling or transformation
What We Do
GeneDx is focused on delivering personalized, actionable insights that improve health outcomes. We sit at the intersection of diagnostics and data science, pairing decades of genomic expertise with an unmatched ability to interpret clinical data at scale. Our exome and genome testing is among the best in the industry. We expect that it will be even more advanced in the future with the help of Centrellis®, our innovative health information platform. Powered by millions of medical records, Centrellis® integrates digital tools with artificial intelligence to ingest and synthesize clinical and genomic data. As a result of our robust test menu, including our exome and genome testing, and the comprehensive insights generated by Centrellis®, we are developing a more complete understanding of complex disease than ever before. This translates to faster diagnosis, more effective treatment plans, and enhanced drug discovery. Our offerings help a whole spectrum of healthcare partners -- clinicians, researchers, health systems, pharmaceutical companies, and payors -- improve patient experiences and advance population health







