Sr. Dir., Strategic Technology Initiatives Lead

Posted 2 Days Ago
Be an Early Applicant
12 Locations
Remote or Hybrid
231K-385K Annually
Senior level
Artificial Intelligence • Healthtech • Machine Learning • Natural Language Processing • Biotech • Pharmaceutical
We’re in relentless pursuit of breakthroughs that change patients’ lives.
The Role
Leads Pfizer’s strategic technology initiatives across eight Digital Core Platforms, aligning enterprise architecture, AI programs, reuse, governance, and delivery. Oversees Senior Technical Architects, sets portfolio priorities, resolves cross-program trade-offs, advises executive stakeholders, and develops senior technical talent. Establishes responsible AI-enabled delivery practices and ensures reliability, security, documentation, operational excellence, and measurable outcomes across a complex global technology portfolio.
Summary Generated by Built In
ROLE SUMMARY
We are seeking a Senior Director, Strategic Technology Initiatives Lead to lead and connect Pfizer's most important strategic technology initiatives with our eight Digital Core Platforms. This leader will oversee a team of Senior Technical Architects and own the connected strategy that ensures high-priority, Executive Leadership Team (ELT)-level AI programs are designed, aligned, and delivered as a coherent whole across the platform landscape.
The role is accountable for connecting the technical strategy of individual initiatives into one coherent direction, ensuring each program reinforces the eight Digital Core Platforms rather than diverging from them. Working with senior business and Digital leaders, this leader sets priorities across initiatives, resolves cross-program trade-offs, and ensures the right architects and technical talent are aligned to the most important outcomes.
This position requires a senior leader with strong leadership, communication, and organizational skills who can operate at the intersection of strategy, architecture, platform alignment, and organizational leadership. The Senior Director will create clarity from complexity, orchestrate work across many initiatives and teams, develop senior technical talent, and establish a practical, connected strategy that helps Pfizer deliver faster, safer, and more reusable digital capabilities at global scale.
ROLE RESPONSIBILITIES
  • Connected Technology Strategy: Own the connected technology strategy across the strategic technology initiatives, ensuring each initiative aligns to and strengthens the eight Digital Core Platforms and Pfizer's enterprise architecture standards.
  • Platform Alignment and Reuse: Ensure the strategic initiatives make deliberate, reusable use of the eight Digital Core Platforms, driving consistency, reuse, and clean integration rather than duplicated or divergent solutions.
  • ELT-Level Initiative Leadership: Lead the technical strategy and senior stakeholder alignment for key Executive Leadership Team (ELT)-level AI programs, translating ambiguous enterprise priorities into a coordinated set of initiatives with clear owners, delivery models, and measurable outcomes.
  • Architect Team Leadership: Oversee, lead, and develop a team of Senior Technical Architects, setting direction, balancing workload across initiatives, and ensuring consistent architecture quality and standards across the portfolio.
  • AI-Enabled Delivery: Define how AI, automation, and modern engineering practices are responsibly applied across the initiatives to increase speed, improve quality, strengthen decision-making, and maintain appropriate governance and verification.
  • Leadership, Communication, and Organization: Provide clear leadership and set direction with strong, structured communication; organize and coordinate work across many initiatives, architects, and stakeholders; and build a high-performing, inclusive team culture of accountability and continuous learning.
  • Governance and Delivery Assurance: Establish expectations for reliability, security, documentation, and operational excellence across the initiatives, and provide the governance and reporting that keep senior leaders informed and the portfolio on track.

ROLE BEHAVIOURS
  • Don't Lose Your Curiosity: Fosters a culture of curiosity and continuous learning across the initiatives and architect team; sponsors experimentation and cross-initiative learning; brings emerging technologies and outside-in perspectives into the connected strategy
  • Set an example for your team: Consistently demonstrate a clear vision, positive energy, and exemplary leadership that motivate the architect team and initiative stakeholders to strive for their highest potential
  • Own the Outcome: Sets clear accountability standards focused on business impact and connected delivery; takes end-to-end ownership of outcomes across the portfolio of initiatives; drives quality and delivery commitments in the AI era
  • Connect Across Disciplines: Connects work across initiatives, architects, platforms, and business domains; inspires holistic solutions and reuse; translates specialized knowledge into accessible explanations; thinks like a business insider
  • Communicate with Precision: Communicates with exceptional clarity and structure; frames trade-offs and priorities crisply; tailors the message from ELT sponsors to engineers; drives clarity and alignment as a core value across the portfolio
  • Think in Systems: Shapes systems design and architecture practices across the initiatives; connects programs into a coherent whole; anticipates dependencies and risks; influences cross-team architecture decisions; creates clarity from complexity

QUALIFICATIONS
Basic Qualifications
  • Bachelor's degree in Computer Science, Engineering, Information Systems, or a related field, with 12+ years of significant leadership experience in technology strategy, architecture, or large-scale program delivery.
  • Demonstrated experience leading the technology strategy and delivery of multiple concurrent programs or initiatives, and connecting them into a coherent whole.
  • Proven ability to lead and develop senior technical talent, including architects, principal engineers, and other senior specialists.
  • Experience advising senior leaders on technology direction, priorities, trade-offs, and measurable business outcomes.
  • Strong understanding of modern engineering practices, cloud platforms, data and integration patterns, AI-enabled delivery, security, reliability, and technology governance.

Preferred Qualifications
  • Advanced degree in technology, engineering, business, or a related discipline preferred.
  • Experience operating in a highly regulated, global enterprise environment with complex compliance, privacy, security, and risk expectations.
  • Experience connecting multiple programs, platform portfolios, and AI-enabled initiatives into a coherent enterprise strategy.
  • Track record of influencing C-suite or enterprise leadership teams, building trusted partnerships, and creating clarity in ambiguous, high-impact situations.
  • Demonstrated strength in leading large, cross-functional teams with exceptional communication, organization, and stakeholder management.

Leadership Capabilities
  • Connected Strategy and Judgment: Connects the strategy of individual initiatives, the eight Digital Core Platforms, and enterprise architecture into one practical, connected direction that guides investment and execution.
  • Leadership and Communication: Leads with clarity and confidence; communicates with exceptional precision and structure; organizes and coordinates complex work across many teams; frames trade-offs, builds alignment, and drives decisions.
  • Technical Depth and Breadth: Brings enough hands-on technical and architectural credibility to guide senior architects, challenge assumptions, evaluate emerging technologies, and make sound enterprise-scale choices.
  • Talent Leadership: Develops senior technical leaders and architects, builds succession plans, strengthens team capability, and creates an inclusive culture of accountability, curiosity, and continuous learning.
  • AI and Modern Delivery Mindset: Understands how AI, automation, modern engineering, product thinking, and platform reuse can improve speed, quality, and value while maintaining appropriate controls and verification.

Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
Work Location Assignment: Hybrid
Additional Posting Locations: Tampa, FL, Collegeville, PA, Groton, CT, La Jolla, CA, Bothell, WA, Canada, Greece, Ireland, Switzerland and Walton Oaks (UK). On site strongly preferred. Remote locations will only be considered for internal candidates who are already designated remote.
Last Date to Apply for Job: 9/28/2026
The annual base salary for this position ranges from $230,900.00 to $384,800.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 25.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.
Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email [email protected] . This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers .
Information & Business Tech
#BI-Hybrid

Skills Required

  • Bachelor's degree in Computer Science, Engineering, Information Systems, or a related field
  • 12+ years of significant leadership experience in technology strategy, architecture, or large-scale program delivery
  • Experience leading technology strategy and delivery across multiple concurrent programs or initiatives
  • Experience connecting multiple programs or initiatives into a coherent strategy
  • Experience leading and developing senior technical talent, including architects, principal engineers, or senior specialists
  • Experience advising senior leaders on technology direction, priorities, trade-offs, and measurable business outcomes
  • Strong understanding of modern engineering practices, cloud platforms, data and integration patterns, AI-enabled delivery, security, reliability, and technology governance
  • Advanced degree in technology, engineering, business, or a related discipline
  • Experience in a highly regulated, global enterprise environment with complex compliance, privacy, security, and risk expectations
  • Experience connecting programs, platform portfolios, and AI-enabled initiatives into an enterprise strategy
  • Experience influencing C-suite or enterprise leadership teams and building trusted partnerships
  • Experience leading large, cross-functional teams with strong communication, organization, and stakeholder management
  • Permanent work authorization in the United States

What the Team is Saying

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Esteban
Pfizer

Pfizer Compensation & Benefits Highlights

  • Healthcare Strength Health coverage is described as comprehensive, spanning medical, dental, vision, and robust mental‑health benefits, with eligible Pfizer medications available at no cost in U.S. plans. Family‑building support and transgender‑inclusive care are explicitly included, alongside wellbeing resources such as a reimbursement wallet and telehealth options.
  • Retirement Support Retirement programs feature a 401(k) with company matching plus an additional Retirement Savings Contribution, complemented by company‑subsidized life, short‑term disability, and long‑term disability insurance. Materials also reference subsidized retiree medical coverage for eligible groups.
  • Leave & Time Off Breadth Paid vacation, holidays, personal days, and paid parental and caregiver leave are consistently highlighted in current U.S. summaries and job postings. Options like buying extra vacation days and transition‑back support strengthen the time‑off offering.

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The Company
HQ: New York, NY
121,990 Employees
Year Founded: 1848

What We Do

Our purpose ensures that patients remain at the center of all we do. We live our purpose by sourcing the best science in the world; partnering with others in the healthcare system to improve access to our medicines; using digital technologies to enhance our drug discovery and development, as well as patient outcomes; and leading the conversation to advocate for pro-innovation/pro-patient policies.

Why Work With Us

We are the inventors, the problem solvers, the big thinkers — those who surmount any hurdle to deliver breakthrough medicines to the people who are counting on them the most.

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Pfizer Offices

Hybrid Workspace

Employees engage in a combination of remote and on-site work.

Typical time on-site: 2.5 days a week
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HQHudson Yards
Provincia de Buenos Aires
Andover, MA
Athens, GR
Chennai, IN
Collegeville, PA
Durham, NC
Groton, CT
Madison, NJ
Madrid, ES
Mumbai, Maharashtra
Rochester, MI
San Diego, CA
Seattle, WA
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Tampa, FL
Center for Digital Innovation
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