Sr Computational Biologist

Posted 5 Days Ago
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Boston, MA, USA
In-Office
145K-180K Annually
Senior level
Healthtech • Biotech
The Role
Develop and apply algorithms on multimodal datasets (genomics, clinical outcomes, imaging) to discover biomarkers and therapeutic targets. Lead statistical investigations of oncogenesis, prognostic/predictive markers, drug resistance, and disease monitoring. Manage codebases and dataset versioning, collaborate with clinical partners on translational research and publications, represent the team to cross-functional stakeholders, and communicate complex results to technical and non-technical audiences.
Summary Generated by Built In

About the Job

The Sr Computational Biologist position sits within the Computational Discovery team and is responsible for building advanced algorithms and technical features that will drive R&D’s innovation roadmap. This role leverages multi-modal data, including large scale genomics, real-world clinical outcomes, and imaging datasets, to identify and establish feasibility of novel biomarkers and therapeutic targets. The Sr Computational Biologist contributes as a subject matter expert in cross-functional initiatives to identify opportunities for growth and innovation that can advance FMI’s assay and data product capabilities. This position requires a deep understanding of cancer biology and bioinformatics, as well as the ability to communicate complex findings to internal and external stakeholders. 

Key Responsibilities

  • Utilize statistical expertise to explore multimodal data and lead scientific investigations into mechanisms of oncogenesis, prognostic and predictive biomarkers, drug resistance, and disease monitoring.
  • Manage and/or support code bases/repositories and dataset versioning and quality control.
  • Represent Computational Discovery to cross-functional departments and leadership teams to refine product strategy.
  • Collaborate with clinical partners in translational research projects that result in abstracts and publications.
  • Communicate results to both technical and non-technical stakeholders.
  • Other duties as assigned.

Qualifications:

Basic Qualifications:

  • PhD in a life science or mathematical field with a clinical focus and 4+ years of industry or post-doctorate experience within Cancer Biology, Bioinformatics, Biochemistry, or another related life science; OR Master’s degree in a life science or mathematical field with clinical focus and 6+ years of industry experience within Cancer Biology, Bioinformatics, Biochemistry, or another related field
  • Proficiency with one or more of the following scientific computing languages: Python, R, Matlab, or Java

Preferred Qualifications:

  • Practical graduate and post-doctoral experience exhibited by first-author publications
  • Subject matter expertise in one of the following areas: cancer genomics, bioinformatics, biostatistics, or machine learning
  • Working knowledge of NGS technology, biomarker development, and real-world clinical outcomes
  • Working knowledge of clinical nomenclature including line of therapy, stage, ECOG, and the patient journey in oncology
  • Experience with computational technologies such as databases (SQL), cloud computing (AWS), and deep learning (AI)
  • Experience managing collaborations with multiple stakeholders
  • Experience mentoring and developing junior scientists
  • Translational research experience and ability to analyze and critically interpret scientific literature
  • Understanding of HIPAA and the importance of patient data privacy
  • Commitment to reflect FMI’s values: Integrity, Courage, and Passion 

The expected salary range for this position based on the primary location of Boston, MA is $145,000 - $180,000 per year. The salary range is commensurate with FMI’s compensation practice and considers factors including, but not limited to, education, training, experience, external market conditions, criticality of role, and internal equity. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for FMI benefits.

#LI-Onsite

About Us
Foundation Medicine, Inc. (FMI) is a global, patient-focused precision medicine company delivering high-quality, transformative diagnostic solutions in cancer and other diseases.

Foundation Medicine is proud to be an Equal Opportunity and Affirmative Action employer and considers all qualified applicants for employment without regard to race, color, religion, sex, gender, sexual orientation, gender identity, ancestry, age, or national origin.  Further, qualified applicants will not be discriminated against on the basis of disability or protected veteran status.  We also consider qualified applicants regardless of criminal histories, consistent with legal requirements.  See also FMI's EEO Statement and EEO is the Law and Supplement.  If you have a disability or special need that requires accommodation, please let us know by completing this form.  (EOE/AAP Employer)

Skills Required

  • PhD in a life science or mathematical field with a clinical focus and 4+ years of industry or post-doctorate experience within Cancer Biology, Bioinformatics, Biochemistry, or related life science
  • Master's degree in a life science or mathematical field with a clinical focus and 6+ years of industry experience within Cancer Biology, Bioinformatics, Biochemistry, or related field
  • Proficiency with one or more scientific computing languages: Python, R, Matlab, or Java
  • Practical graduate and post-doctoral experience exhibited by first-author publications
  • Subject matter expertise in cancer genomics, bioinformatics, biostatistics, or machine learning
  • Working knowledge of NGS technology, biomarker development, and real-world clinical outcomes
  • Working knowledge of clinical nomenclature including line of therapy, stage, ECOG, and the patient journey in oncology
  • Experience with computational technologies such as databases (SQL), cloud computing (AWS), and deep learning (AI)
  • Experience managing collaborations with multiple stakeholders
  • Experience mentoring and developing junior scientists
  • Translational research experience and ability to analyze and critically interpret scientific literature
  • Understanding of HIPAA and importance of patient data privacy
  • Commitment to company values (Integrity, Courage, and Passion)

Foundation Medicine Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Foundation Medicine and has not been reviewed or approved by Foundation Medicine.

  • Strong & Reliable Incentives Bonuses and long-term incentives are described as competitive and a meaningful component of total rewards. Annual bonuses tied to personal and company outcomes feature alongside base pay.
  • Healthcare Strength Comprehensive medical and dental coverage is a core element of the package. Health plans are positioned as robust and well-rounded rather than minimal.
  • Leave & Time Off Breadth Time-off offerings include flexible or unlimited PTO and paid parental leave, supporting work–life balance. Extra paid downtime has been referenced alongside standard PTO.

Foundation Medicine Insights

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The Company
HQ: Boston, MA
1,844 Employees
Year Founded: 2010

What We Do

Foundation Medicine is a molecular information company dedicated to a transformation in cancer care in which treatment is informed by a deep understanding of the genomic changes that contribute to each patient's unique cancer. The company offers a full suite of comprehensive genomic profiling assays to identify the molecular alterations in a patient’s cancer and match them with relevant targeted therapies, immunotherapies and clinical trials. Foundation Medicine’s molecular information platform aims to improve day-to-day care for patients by serving the needs of clinicians, academic researchers and drug developers to help advance the science of molecular medicine in cancer. For more information, please visit us at www.FoundationMedicine.com or follow @FoundationATCG on Twitter. Community Guidelines: bit.ly/FMICommunityGuidelines

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