In this pivotal role, you’ll serve as the backbone of Twist’s data infrastructure—enhancing our dbt pipelines, driving scalable architecture, and ensuring data flows efficiently across the business. You’ll partner with technical teams and business leaders to transform raw data into trusted insights that fuel decision-making, accelerate innovation, and help bring our breakthrough products to scientists around the world. If you’re passionate about building elegant, resilient systems that make data truly impactful we’d love to meet you.
Key Responsibilities- Maintain and improve dbt data transformation pipelines
- Build and refactor semantic models using best practices
- Optimize workflows for performance, scalability, and reliability
- Support CI/CD adoption and enforce version control standards (e.g., Git)
- Ensure pipeline health and data quality with robust logging and alerting
- Collaborate with analysts and business stakeholders to deliver high-impact solutions
- Document architecture and contribute to a culture of continuous improvement
- Design, build, and optimize scalable data pipelines and architectures within Snowflake
- Implement permissions and role-based access control in Snowflake to manage secure data access
- Bachelor’s degree (or equivalent experience) in Computer Science, Data Engineering, or Analytics
- Clear, confident communication and a collaborative mindset
- Thought leader in data engineering and architecture best practices
- Strong troubleshooting and system optimization skills
- Proficiency in dbt, SQL, and semantic modeling
- Working knowledge of Python or R for data processing
- Experience with CI/CD and Git-based workflows
- Familiarity with modern data infrastructure (e.g., Snowflake, Databricks, Airflow)
About Twist Bioscience
Twist Bioscience synthesizes genes from scratch, known as “writing” DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.
At Twist Bioscience, we work in service of people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.
Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.
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What We Do
Twist Bioscience is a synthetic biology company based in South San Francisco, California. The company has developed a proprietary silicon-based manufacturing process for the production of synthetic DNA.
Twist Bioscience serves Life Science researchers who are changing the world for the better. Coming from diverse fields of medicine, agriculture, industrial chemicals and data storage, scientists use our synthetic genes, oligo pools, and NGS target enrichment to better lives and improve the sustainability of the planet.
Twist Bioscience is uniquely positioned to help accelerate these efforts by providing precision at a scale that is otherwise unavailable. Our technology overcomes inefficiencies and enables cost-effective, rapid, precise, high-throughput DNA synthesis and sequencing. We offer both the quality and quantity researchers need now to rapidly realize opportunities ahead.
