Senior Vice President Human Resources

At Caris, we understand that cancer is an ugly word—a word no one wants to hear, but one that connects us all. That’s why we’re not just transforming cancer care—we’re changing lives.

We introduced precision medicine to the world and built an industry around the idea that every patient deserves answers as unique as their DNA. Backed by cutting-edge molecular science and AI, we ask ourselves every day: “What would I do if this patient were my mom?” That question drives everything we do.

But our mission doesn’t stop with cancer. We're pushing the frontiers of medicine and leading a revolution in healthcare—driven by innovation, compassion, and purpose.

Join us in our mission to improve the human condition across multiple diseases. If you're passionate about meaningful work and want to be part of something bigger than yourself, Caris is where your impact begins.

Position Summary

Caris Life Sciences is seeking an experienced and trusted Senior Vice President of Human Resources to provide strategic leadership and guidance to our established HR function. Reporting to the Chief Financial Officer, this executive will oversee all areas of Human Resources, including HR strategy, operations, talent, total rewards, and employee relations.
This individual will lead a capable HR team with a solid foundation already in place, focusing on enhancing and evolving the current structure to support continued growth and business success. The ideal candidate brings extensive experience in a traditional, structured HR environment, is humble and approachable in style, and possesses the judgment and influence to work effectively with executive leadership

Job Responsibilities
•    Strategic Leadership
o    Define and lead the company’s human resources strategy in alignment with business and financial objectives.
o    Provide vision, structure, and direction to all aspects of HR, ensuring consistency, compliance, and operational excellence.
o    Partner with the CFO and executive team to anticipate organizational needs and proactively address workforce and leadership planning.
•    Organizational and Talent Leadership
o    Help to guide long-term workforce and succession planning to ensure organizational stability and readiness for future growth.
o    Oversee leadership and management development efforts that strengthen capability and reinforce a culture of accountability and respect.
•    Operational Excellence and Governance
o    Help to refine and enhance existing HR systems, processes, and policies to ensure reliability, scalability, and compliance.
o    Establish clear performance measures and reporting cadence to assess HR effectiveness and alignment with company objectives.
•    Compensation, Benefits, and HR Operations
o    Provide oversight and direction for total rewards strategy, ensuring competitiveness, internal equity, and fiscal discipline.
o    Partner with the current HR Leadership to optimize HR systems, data integrity, and service delivery to employees.
•    Employee Relations and Compliance
o    Uphold a consistent, fair, and legally compliant work environment across all locations.
o    Maintain oversight of employee relations policies and practices, ensuring risk mitigation and trust in company processes.
•    Culture and Leadership Influence
o    Champion a positive, inclusive, and performance-oriented culture that supports the company’s values and mission.
o    Serve as a trusted advisor to senior leadership, providing sound counsel and balanced judgment on complex people matters

Required Qualifications
•    Bachelor’s degree required 
•    15+ years of Human Resources leadership experience, including significant experience in senior-level or enterprise HR roles.
•    Demonstrated success leading HR functions in traditional, structured, and compliance-focused organizations.
•    Proven ability to lead and develop high-performing HR teams and leaders.
•    Deep understanding of core HR disciplines including compensation, benefits, employee relations, compliance, and HR operations.
•    Strong executive presence with the ability to influence and collaborate across senior leadership.
•    ; advanced degree or professional HR certification (SPHR, SHRM-SCP) preferred.

Preferred Qualifications
•    Advanced degree or professional HR certification (SPHR, SHRM-SCP) 

Physical Demands
•    Must possess ability to sit and/or stand for long periods of time.
•    Must possess ability to perform repetitive motion.
•    Ability to lift up to 25 pounds.
Training
•    All job specific, safety, and compliance training are assigned based on the job functions associated with this employee.
Other
•    This position requires travel and some evenings, weekends and/or holidays.

Conditions of Employment:  Individual must successfully complete pre-employment process, which includes criminal background check, drug screening, credit check ( applicable for certain positions) and reference verification.

This job description reflects management’s assignment of essential functions. Nothing in this job description restricts management’s right to assign or reassign duties and responsibilities to this job at any time.

Caris Life Sciences is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, gender, gender identity, sexual orientation, age, status as a protected veteran, among other things, or status as a qualified individual with disability.