Senior Software Engineer (Python / AWS / React) – Clinical Data Platform

Posted 2 Days Ago
Be an Early Applicant
Hiring Remotely in CZE
Remote
Senior level
Information Technology • Analytics • Consulting • Cybersecurity
The Role
Develop and maintain a cloud-native clinical data platform using Python, AWS, React, and TypeScript. Build data transformation pipelines, Lambda services, Step Functions workflows, GraphQL APIs, event-driven systems, infrastructure automation, and large-scale Databricks processing. Troubleshoot production issues, improve CI/CD, participate in architecture decisions, conduct code reviews, and mentor junior engineers. The platform transforms clinical trial data into CDISC SDTM standards supporting regulatory submissions and pharmaceutical research.
Summary Generated by Built In

This is a remote position.

Join a team building the Clinical Data Layer, a cloud-native platform that transforms and standardizes clinical trial data into the CDISC SDTM model used for regulatory submissions and clinical research.

You'll develop both backend and frontend components of a modern AWS-based platform, designing scalable data pipelines, APIs, and analyst-facing applications. This role combines cloud engineering, backend development, infrastructure automation, and modern frontend technologies.

The platform directly supports clinical trial analysis, drug development, and regulatory compliance.

Responsibilities
  • Design and extend cloud-native clinical data transformation pipelines
  • Develop Python services running on AWS Lambda
  • Build workflows using AWS Step Functions
  • Develop GraphQL APIs with AWS AppSync
  • Contribute to the React + TypeScript frontend
  • Design scalable event-driven distributed systems
  • Manage infrastructure using Terraform
  • Develop large-scale data processing solutions with Databricks
  • Participate in architecture design and technical discussions
  • Perform code reviews and mentor junior engineers
  • Improve CI/CD pipelines using GitHub Actions
  • Troubleshoot production issues across AWS services
  • Write clean, testable, maintainable code


RequirementsExperience
  • 7+ years of Software Engineering experience
Programming
  • Python
  • Pytest
  • Lambda Powertools
  • Object-Oriented Design
  • Clean Architecture
  • Testing
AWS
  • AWS Lambda
  • AWS Step Functions
  • Amazon S3
  • DynamoDB
  • IAM

Candidates should understand:

  • scalability
  • latency
  • fault tolerance
  • distributed systems
  • cost optimization

—not simply how to use AWS services.

Nice-to-Have
Backend
  • GraphQL
  • AWS AppSync
  • Event-driven architecture
  • Distributed systems
  • Idempotency
  • Fan-out / Fan-in
Frontend
  • React
  • TypeScript
  • Vite
  • AWS Cloudscape
Infrastructure
  • Terraform
  • Infrastructure as Code
Data
  • Databricks
  • Spark
  • Large-scale data platforms
DevOps
  • GitHub Actions
  • CI/CD
  • Black
  • Flake8
  • Pylint
  • Bandit
  • invoke
Domain

Highly desirable:

  • CDISC SDTM
  • ADaM
  • Clinical Trials
  • GxP
  • 21 CFR Part 11
  • Pharmaceutical industry
Tech Stack

Languages

  • Python
  • TypeScript

Cloud

  • AWS Lambda
  • AWS Step Functions
  • S3
  • DynamoDB
  • IAM

API

  • GraphQL
  • AWS AppSync

Frontend

  • React
  • TypeScript
  • Vite
  • Cloudscape

Infrastructure

  • Terraform

Data

  • Databricks

Search

  • OpenSearch

CI/CD

  • GitHub Actions

Testing

  • Pytest
  • pytest-bdd


Benefits
  • Location: EU
  • Contract Type: Freelance / Contract
  • Start date: June/July, 2026
  • Time Allocation: 40 hours/week
  • Global Pharmaceutical Company in Prague​


Skills Required

  • 7+ years of software engineering experience
  • Python experience
  • Pytest experience
  • Lambda Powertools experience
  • Object-oriented design knowledge
  • Clean architecture knowledge
  • Testing experience
  • AWS Lambda experience
  • AWS Step Functions experience
  • Amazon S3 experience
  • DynamoDB experience
  • IAM knowledge
  • Understanding of scalability, latency, fault tolerance, distributed systems, and cost optimization
  • GraphQL experience
  • AWS AppSync experience
  • Event-driven architecture experience
  • Distributed systems experience
  • React experience
  • TypeScript experience
  • Vite experience
  • AWS Cloudscape experience
  • Terraform and infrastructure-as-code experience
  • Databricks and Spark experience
  • GitHub Actions and CI/CD experience
  • CDISC SDTM, ADaM, clinical trials, GxP, or 21 CFR Part 11 experience
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The Company
Year Founded: 2015

What We Do

futureproof s.r.o. is a Czech consulting and staffing firm focused on data, analytics, cybersecurity, and IT infrastructure. It provides contract and permanent staffing, team augmentation, time-and-material resources, and specialist or lead placements, while also offering expert consulting through a network of architects and project leaders. The company emphasizes niche technical expertise, trusted relationships, continuous learning, and long-term value for clients.

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