“This role is expected to model our Leadership Behaviors—Integrity & Compliance, Customer Focus, Collaboration, Courage, Team Empowerment, and Accountability & Results—in all aspects of work.”Key Responsibilities
- Design, develop, and optimize affinity chromatography–based purification processes for diverse biopharmaceutical modalities
- Execute high-throughput chromatographic screening and apply DOE methodologies to accelerate process development
- Analyze, interpret, and communicate complex datasets to drive decision-making and support partner adoption of new technologies
- Collaborate cross-functionally with internal teams (chemistry, analytics, commercial) to deliver integrated purification solutions
- Contribute to multiple development programs, ensuring timely execution and high-quality scientific output
- Innovate and propose novel approaches to improve purification performance, selectivity, and scalability
- Engage with external biopharma partners as a technical expert and scientific collaborator
- MS or PhD in Biochemistry, Chemical Engineering, Biochemical Engineering, or related field
- Minimum of 5 years of hands-on experience in downstream processing and protein purification; including FPLC
- Experience across multiple modalities (e.g., proteins, enzymes, vaccines, VLPs, gene therapy vectors)
- Expertise in chromatography method development, including automated/high-throughput systems
- Strong proficiency with Design of Experiments (DOE) for process optimization
- Working knowledge of analytical techniques (e.g., purity/impurity analysis, potency, stability assays)
- Broad scientific understanding spanning separations, protein chemistry, and bioprocessing
- Strong communication skills with the ability to translate data into clear, actionable insights
- Self-motivated, collaborative, and effective in a fast-paced, innovation-driven environment
Our mission is to inspire advances in bioprocessing as a trusted partner in the production of biologic drugs that improve human health worldwide. Focused on cost and process efficiencies, we deliver innovative technologies and solutions that help set new standards in bioprocessing. The estimated salary range for this role, based in the United States of America is $115,000/yr. -$145,000/yr.
Compensation decisions are dependent on several factors including, but not limited to an individual's qualifications, location, internal equity, and alignment with market data. Additionally, employees are eligible to participate in one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits such as paid time off, health/dental/vision, retirement benefits and flexible spending accounts. All compensation and benefits information will be confirmed in writing at the time of offer.
Skills Required
- MS or PhD in Biochemistry, Chemical Engineering, Biochemical Engineering, or related field
- Minimum of 5 years hands-on experience in downstream processing and protein purification, including FPLC
- Experience across multiple modalities (proteins, enzymes, vaccines, VLPs, gene therapy vectors)
- Expertise in chromatography method development, including automated/high-throughput systems
- Strong proficiency with Design of Experiments (DOE) for process optimization
- Working knowledge of analytical techniques (purity/impurity analysis, potency, stability assays)
- Broad scientific understanding spanning separations, protein chemistry, and bioprocessing
- Strong communication skills with ability to translate data into clear, actionable insights
- Self-motivated, collaborative, and effective in a fast-paced, innovation-driven environment
What We Do
FRAUD ALERT: Please take note that it has come to our attention that individuals purporting to work for Repligen are reaching out to prospective job applicants using fraudulent email addresses. All legitimate communications from Repligen will be sent from an individual with an email address ending in @repligen.com. If you have any concerns that a communication may be fraudulent and you would like to confirm whether it is, you may email [email protected] and someone will respond. Repligen is a bioprocessing-focused life sciences company bringing over 40 years of expertise and innovation to our customers. We are inspiring advances in bioprocessing through the development and commercialization of high-value products and flexible solutions that address critical steps in the production of biologic drugs, principally monoclonal antibodies. Repligen headquarters is in Waltham, Massachusetts and our manufacturing facilities are located around the world. We market our products globally through a direct commercial organization in the U.S., Europe and Asia, as well as through strategic partners in select markets.
