Senior Scientist, Process Development

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Watertown, MA
In-Office
Biotech
Landmark helps fast-track discovery research and bring life-changing therapies to more patients.
The Role
Landmark Bio is dedicated to translating cutting-edge research into life-changing therapies. Headquartered in Watertown, Massachusetts, the company was founded by leading academic institutions, research hospitals, and industry partners to accelerate the development, manufacturing, and commercialization of advanced therapies. Driven by the compelling science and transformative potential of genetic medicine, Landmark Bio offers deep drug development expertise and integrated end-to-end solutions to support its partners. The company also serves as a collaborative platform to advance next-generation manufacturing technologies for novel modalities. Following its acquisition by Artis BioSolutions in 2025, Landmark Bio continues to operate as a distinct entity.  Learn more at www.landmarkbio.com
 
We are seeking a highly motivated and team-oriented professional with entrepreneurial spirit to join our company! This is an exciting opportunity for a well-qualified candidate to join a rapidly growing company focused on turning today’s cutting-edge research into tomorrow’s breakthrough therapies.

We are seeking a Senior Scientist, Process Development, responsible for executing cell culture experiments, downstream processing, analyzing data, and contributing to process development projects. The ideal candidate will be involved in troubleshooting complex issues. The position requires a strong understanding of all aspects of mammalian cell culture and aseptic technique, ability to use small-scale bioreactors and purification principles, and experience in data analysis and scientific writing.  This is a hands-on lab-based position requiring a flexible schedule based on experimental work; some weekend work may be required.
 
Responsibilities:
·       Culture and purify different cell types including iPSC and MSC cells.
·       Maintain small-scale bioreactors from 0.5mL to 10L scale.
- Cell transfection, transduction, and other genetic manipulation techniques. 
- Use of purification techniques such as affinity and anion exchange chromatography and filtration-based unit operations.
·       Performance of general laboratory tasks, including maintenance of equipment.
·       Maintain accurate and reliable records including database management, batch records, lab notebooks, and all other pertinent documentation.
·       Write and/or contribute to SOPs, batch records, protocols and reports.
·       Comply with all safety and infection control standards.
 
Qualifications
·       Bachelor’s degree with minimum 10 years relevant experience or Ph.D with 2-4 years’ experience in biology, bioengineering, biotechnology, or related discipline.
·       Strong understanding of tissue culture and aseptic technique.
·       Willingness to work with different viral vector systems (lentiviral and AAV) and biological samples.
·       Strong team worker who is also independently motivated, detail oriented with good problem-solving capabilities.
·       Strong verbal and written skills; able to handle confidential information and material appropriately.
·       Background in cell-based methods and bioreactors and/or downstream purification experience.

Landmark Bio is an Equal Opportunity, Affirmative Action employer. Minorities, women, veterans, and individuals with disabilities are encouraged to apply.

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law may be subject to criminal penalties and civil liability.

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The Company
HQ: Watertown, MA
81 Employees
Year Founded: 2021

What We Do

Landmark Bio is a collective endeavor launched by leaders from academia, the life sciences industry, and world-renowned research hospitals to accelerate development and industrialization of next-generation genomic medicine.

Inspired by recent advancements in cell and gene therapy, Landmark Bio was established to remove barriers in drug development, create accessible capability, expertise, and solutions, and offer a collaboration platform to advance manufacturing technologies for the new generation of medicines to come. Founding partners include Harvard University, Massachusetts Institute of Technology (MIT), Cytiva, FUJIFILM Diosynth Biotechnologies (FDB), and Alexandria Real Estate Equities, Inc. Other collaborating institutions include Beth Israel Deaconess Medical Center, Boston Children’s Hospital, Mass General Brigham, and the Dana-Farber Cancer Institute.

For more information please contact [email protected]

Why Work With Us

Landmark Bio was conceived to accelerate life sciences innovation. Our cross-sector network, expert staff and consultants, state-of-the-art facility, and broad definition of how a true partner can expedite translational research make us unique.

Our mission Is to translate groundbreaking research into life-changing therapies.

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