Company Overview: Terray Therapeutics is a venture-backed biotechnology company led by pioneers and long-time leaders in artificial intelligence, synthetic chemistry, automation, and nanotechnology. We’re generating chemical data purpose-built to propel drug discovery into the information age — and we’re doing it on a larger scale and faster than has ever before been possible.
Our closed loop system generates precise chemical datasets at unrivaled scale that work seamlessly with AI to systematically map biochemical interactions between small molecules and causes of disease. Iterative cycles of virtual molecular design and experimentation power AI and machine learning models, which in turn guide the next cycle of design. With a chemistry engine that measures billions of interactions daily and becomes increasingly precise with every cycle, we can answer an unprecedented array of questions — deriving insights that enable us to predictably create drugs for patients in need.
Position Summary: Terray is currently seeking a motivated, creative, and experienced scientist to join our molecular design (MoDe) group. As part of the Computational and Data Sciences (CDS) team, the candidate will help drive hit validation and advance programs through hit‑to‑lead by using our unique chemical datasets and integrated wet‑lab + computational technologies. A hallmark of this role is the close, day‑to‑day partnership with our medicinal chemistry, biology, and ML teams. MoDe scientists work hand‑in‑hand with wet‑lab colleagues throughout each design–make–test cycle, ensuring fast experimental feedback, shared problem‑solving, and seamless connection between computational design and laboratory execution. Crucial for this execution is collaboration with machine learning and data science teams in CDS.
The core responsibilities of this position are:
- Design small molecules with in-house, high-throughput computational tools using both structural models and ligand-based data from our proprietary screening platform
- Lead chemistry efforts for multiple internal pipeline and partnered projects with ownership and clear communication of design strategies
- Manage external synthetic chemistry team(s) to effectively prioritize work to reach project goals
- Utilize Terray chemical technologies to design focus libraries to drive small molecule programs toward lead optimization
- Collaborate on development and evaluation of models and generative tools for compound design with the machine learning team
- Communicate molecular design strategy and outcomes to teams across the company
Experience and Qualifications: Part of Terray’s success is nurtured by a hands-on work environment where everyone is accountable, vested in a vision of excellence, and actively taking part in the success of the business. Terray supports a positive work environment where employees can feel engaged, recognized and empowered to be creative.
Required Qualifications:
- BS/MS/Ph.D in computational, organic, or medicinal chemistry with 4+ years of industry experience
- Experience with the application of ligand- and structure-based computational tools for molecular design
- Fluent in optimization of ADME and safety issues with the ability to communicate team strategies
- Experience with triage of large data sets from virtual screens, DEL screens, and/or HTS
- Excellent communication skills with experience conveying medicinal chemistry results cross-functionally
- Proven, or developing, program leadership experience
- Familiarity with the management of external chemistry teams
Compensation Details: $160,000 - $240,000 (annually) depending on experience; participation in the Company's option plan; 3% retirement safe harbor contribution; fully-paid medical, dental, vision, life and disability benefits.
What We Do
Chemistry is the key to drug discovery, but chemical data is stuck in the twentieth century. We’re generating precise chemical datasets purpose-built to propel drug discovery into the information age — and we’re doing it on a larger scale and faster than has ever before been possible. Terray Therapeutics is a biotechnology company led by pioneers and long-time leaders in artificial intelligence, synthetic (medicinal) chemistry, biology and preclinical development, automation, and nanotechnology. Chemical datasets generated using our novel ultra-dense microarray technology work seamlessly with our integrated machine learning and computational platform to systematically map biochemical interactions between small molecules and causes of disease. Iterative cycles of virtual molecular design and experimentation power AI and machine learning models, which in turn guide the next cycle of design. With a chemistry engine that measures billions of interactions daily and becomes increasingly precise with every cycle, we can answer an unprecedented array of questions — deriving insights that enable us to predictably create drugs for patients in need.
