Senior Scientist I, Analytical Development

Posted 5 Days Ago
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San Diego, CA, USA
In-Office
Senior level
Healthtech • Pharmaceutical
The Role
Support characterization and method development for mRNA-targeted lipid nanoparticles (tLNPs). Independently perform icIEF, HPLC, CE, and plate-based assays to assess content, purity, and integrity. Develop and re-optimize analytical and nanoparticle characterization methods (SEC, MALS, CZE, LC-MS), improve assay efficiency through automation, and author technical reports.
Summary Generated by Built In
Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.

Job Description

The Opportunity
We seek a Senior Scientist I, Analytical Development to join an experienced, fast-paced and collaborative team. This position will be primarily responsible for supporting characterization of AbbVie’s mRNA-based targeted lipid nanoparticles (tLNPs) pipeline. This role will focus on executing testing methods for characterizing mRNA/tLNPs and supporting development of new tLNP characterization methods. Working collaboratively across the discovery research team, this position will support process/product characterization, expansion of the mRNA/tLNP pipeline, method development, and platform development.

Responsibilities & Duties:

  • Independently perform icIEF, HPLC, CE, and plate-based assay testing of mRNA and tLNP products for characterizing content, purity/impurities, and integrity
  • Support development of novel nanoparticle characterization techniques, including but not limited to icIEF, SEC, MALS, CZE, LC-MS, etc
  • Re-optimize analytical methods to support new programs and platform improvements
  • Improve routine assay efficiency through automation and assay/workflow improvements
  • Author technical reports and documents as needed

Qualifications

  • Bachelors, Masters, or Ph.D. in Analytical Chemistry typically with a minimum of 10 (BS), 8 (MS), or 0 (Ph.D.) years related industry experience.
  • Strong technical background in analytical chemistry, excellent analytical problem-solving skills. Capable of independently developing and troubleshooting analytical methods.
  • Degree in Biochemistry, Chemistry, Bioengineering, Chemical Engineering or related field with experience testing and developing analytical characterization methods for biologics (e.g. antibodies, mRNA, etc) is required.
  • Experience with nanoparticle and/or small molecule characterization is preferred
  • Demonstrate creative 'out of the box' thinking to solve difficult problems
  • Experience with icIEF, HPLC, Capillary Electrophoresis (CE), and plate-based assays required
  • Proficiency authoring and reviewing technical reports
  • Strong communication skills, both written and verbal, with a demonstrated capacity to thrive in collaborative, team-driven environments.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

  • The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this roleat  the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on manyfactors  including  geographic location, and we may ultimately  pay more or less than the posted range. This range may be  modified in the future. ​

  • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​

  • This job is eligible to  participate in our short-term incentive programs. ​

Note: No amount of pay is  considered to be wages or compensation until such amount isearned,  vested,  and determinable. The amount and availability of  any bonus, commission, incentive, benefits, or any other form of compensation and benefits that areallocable to a   particular employee  remains in the Company's sole and absolute discretion unless and until paid and may be  modified at the Company’s sole and absolutediscretion,  consistent with applicable law. 

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled. 

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

Skills Required

  • Bachelors, Masters, or Ph.D. in Analytical Chemistry, Biochemistry, Chemistry, Bioengineering, Chemical Engineering or related field with relevant industry experience.
  • Minimum industry experience per degree: BS ~10 years, MS ~8 years, PhD ~0 years (as stated).
  • Strong technical background in analytical chemistry with independent method development and troubleshooting skills.
  • Experience testing and developing analytical characterization methods for biologics (e.g., antibodies, mRNA).
  • Experience with icIEF, HPLC, Capillary Electrophoresis (CE), and plate-based assays.
  • Proficiency authoring and reviewing technical reports and technical documentation.
  • Strong written and verbal communication and ability to work collaboratively in team environments.
  • Experience with nanoparticle and/or small molecule characterization techniques.
  • Demonstrated creative problem-solving and ability to develop novel nanoparticle characterization approaches (e.g., SEC, MALS, CZE, LC-MS).
  • Experience improving assay efficiency through automation and workflow improvements.

AbbVie Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about AbbVie and has not been reviewed or approved by AbbVie.

  • Retirement Support 401(k) contributions include a dollar-for-dollar match up to 6% plus an additional annual company contribution tied to age and service. Company-paid life insurance and other financial protections further strengthen long-term security.
  • Parental & Family Support Paid leave programs include up to 12 weeks at 100% for parental leave and separate paid caregiver leave, with eligibility after six months where noted. Adoption and surrogacy reimbursements and family-building resources add further support.
  • Healthcare Strength Health coverage begins on day one with medical, dental, vision, mental health, and prescription benefits, and preventive care covered at 100%. Options such as HSAs/FSAs and coverage for spouses/domestic partners and children up to age 26 broaden accessibility.

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The Company
HQ: Chicago, IL
50,000 Employees
Year Founded: 2013

What We Do

AbbVie is a global biopharmaceutical company focused on creating medicines and solutions that put impact first — for patients, communities, and our world. We aim to address complex health issues and enhance people's lives through our core therapeutic areas: immunology, oncology, neuroscience, eye care, aesthetics and other areas of unmet need.

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