Senior Scientist, Discovery Process Research

Posted 8 Days Ago
Be an Early Applicant
Spring House, PA, USA
In-Office
Senior level
Healthtech • Biotech • Pharmaceutical • Manufacturing
The Role
Conduct independent synthetic chemistry research to solve discovery bottlenecks and support development of small molecules, oligonucleotides, peptides, and emerging modalities. Develop efficient synthetic routes, apply advanced organic and analytical chemistry techniques, collaborate across pharmaceutical R&D teams, evaluate scientific literature, and contribute to discovery program direction. The role requires strong laboratory engagement, scientific problem-solving, peer-reviewed research excellence, and effective communication.
Summary Generated by Built In

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com.

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Chemical Research

Job Category:

Scientific/Technology

All Job Posting Locations:

Spring House, Pennsylvania, United States of America

Job Description:

About Innovative Medicine:

 

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine


 

We are searching for the best talent for a Senior Scientist, Discovery Process Research based in Spring House, PA.

 


Purpose:
Our Discovery Process Research team focuses on developing novel synthetic chemistry solutions that enable and accelerate the Discovery of innovative therapeutics to treat diseases with high unmet medical need. You will be responsible for conducting research towards identifying creative solutions for chemistry problems across a portfolio of projects in the discovery space, from lead identification through selection of development candidates. Our goal is to facilitate medicinal chemistry research by finding solutions to synthetic bottlenecks, enabling access to novel chemical space and translating chemistry innovations to the development of efficient routes for the synthesis of small molecules, oligonucleotides, peptides and other emerging modalities advancing into development.

You will be responsible for:
Your work will require state of the art synthetic organic chemistry skills and understanding of analytical chemistry techniques. You are expected to remain conversant with the modern chemical literature and to maintain a strong laboratory presence. Residing at the interface of Discovery and Development, Discovery Process chemists thrive by collaborating across multiple Pharmaceutical R&D disciplines. Unique to this role, Senior Scientists in Discovery Process are expected to operate with a high degree of independence for scientific decision-making to contribute to the direction and execution of Discovery programs from very early in their careers.

Education:

  • Minimum of a PhD in Synthetic, Organic, Medicinal Chemistry, or related field completed by Spring of 2027 is required

Required:

  • Experience in methodology development, catalysis, total synthesis or similar
  • Proven track record of scientific excellence supported by peer-reviewed publications
  • Ability to collaborate in a highly integrated environment and to work in a strong team with diverse backgrounds.
  • Strong problem-solving skills for developing creative, innovative solutions, and meeting project objectives.
  • Highly motivated candidate with strong commitment to lab work.
  • Excellent oral and written communication skills, fluent in English both verbal and in writing.

Preferred:

  • Hands on knowledge of high throughput experimentation set-ups
  • Experience working in non-small molecule modalities such as peptides (solid or solution phase synthesis), bioconjugates such as ADCs, or proximity inducers



Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. 


Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via https://www.jnj.com/contact-us/careers, internal employees contact AskGS to be directed to your accommodation resource.

#LI-Onsite



Required Skills:



Preferred Skills:

Skills Required

  • PhD in synthetic chemistry, organic chemistry, medicinal chemistry, or a related field, completed by Spring 2027
  • Experience in methodology development, catalysis, total synthesis, or similar
  • Proven scientific excellence demonstrated by peer-reviewed publications
  • Ability to collaborate in a highly integrated, diverse team environment
  • Strong problem-solving skills for developing creative solutions and meeting project objectives
  • Strong commitment to laboratory work
  • Excellent oral and written communication skills in fluent English
  • Hands-on knowledge of high-throughput experimentation setups
  • Experience with non-small-molecule modalities such as peptides, bioconjugates, antibody-drug conjugates, or proximity inducers

Johnson & Johnson Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Johnson & Johnson and has not been reviewed or approved by Johnson & Johnson.

  • Healthcare Strength — Healthcare coverage is characterized as comprehensive across medical, dental, and vision, with added supports like onsite clinics, fitness centers, and Employee Assistance resources. Mental-health services and wellbeing reimbursements are also described as meaningful components of the overall package.
  • Retirement Support — Retirement offerings are portrayed as a major differentiator, combining a 401(k) with employer matching and an employer-funded pension plan. Stock options and other long-term financial supports are also positioned as part of the broader rewards mix.
  • Parental & Family Support — Family-related benefits are presented as notably strong, including paid parental leave for all new parents and additional leave types for caregiving and bereavement. Financial assistance for adoption, fertility treatment, and surrogacy is highlighted as a significant support.

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The Company
HQ: New Brunswick, NJ
143,612 Employees
Year Founded: 1886

What We Do

Profound Change Requires Boldness. Johnson & Johnson is the largest and most broadly based healthcare company in the world. We’re producing life-changing breakthroughs every day, and have been for the last 130 years. The combination of new technologies and your expertise enables amazing things to happen. Teams from J&J’s consumer business are creating digital tools to help people track the health of their skin. Those working in medical devices are 3-D printing artificial joints personalized for each patient, while researchers in pharmaceuticals use AI to discover lifesaving drugs. Imagine what the rest of our team of 134,000 people at 260 companies in more than 60 countries across the world is accomplishing. We redefine what it means to be a big company in today’s world. Social Media Community Guidelines: http://www.jnj.com/social-media-community-guidelines

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