Senior Scientist – Bioprocess Development

We are seeking a passionate and experienced Senior Scientist to lead downstream process development efforts focused on the chromatographic purification of monoclonal antibodies (mAbs). This role is central to our mission of enabling large and small biopharmaceutical companies to bring transformative therapies to patients faster and more efficiently.As a scientific leader, you will guide a small team in designing and executing purification strategies that support late-stage development and manufacturing readiness. You’ll work closely with external biopharma clients, helping them advance their molecules toward commercialization—ultimately impacting patient lives around the world.What You’ll Do

• Design, execute, and analyze chromatography-based purification processes (Protein A, ion exchange, HIC, etc.) for mAbs.
• Develop scalable, robust purification processes tailored to client molecules and manufacturing goals.
• Lead technology transfer activities to external manufacturing sites.
• Author technical reports, protocols, and support regulatory documentation.
• Collaborate directly with major biopharma clients to align on study design, timelines, and deliverables.
• Deliver high-quality experimental results that support their development pipelines and regulatory submissions.
• Serve as a trusted scientific partner, helping clients overcome technical challenges and accelerate their path to market.
• Oversee day-to-day lab operations, including equipment maintenance, inventory, and safety compliance.
• Mentor and guide junior scientists and research associates.
• Foster a culture of scientific rigor, operational discipline, and continuous improvement.

Minimum Qualifications

• M.S. in Biochemistry, Chemical Engineering, Biotechnology, or related field with 8 years of relevant industry experience, or Ph.D. with 5 years of experience in downstream process development for biologics.
• Demonstrated expertise in preparative chromatography and antibody purification.
• Proven ability to lead small scientific teams and manage lab operations.

Preferred Qualifications

• Hands-on experience with AKTA systems, Unicorn software, and high-throughout screening platforms (e.g., Tecan Te-Chrom).
• Proficiency in analytical techniques such as HPLC, SDS-PAGE, ELISA, UV spectroscopy.
• Familiarity with tech transfer, cGMP/cGLP standards, and regulatory documentation.
• Experience in client-facing or CDMO environments is a plus.
• Strong communication, organizational, and problem-solving skills.
• Working knowledge of statistical tools (e.g., JMP,) and data analysis software

Why This Role MattersThis is more than a lab-based leadership role—it’s an opportunity to directly influence the development of biologic therapies that improve and save lives. You’ll be working with some of the world’s leading biopharma companies, helping them refine and scale their purification processes to bring innovative treatments to patients in need.The base salary range for this position is $104,700.00 - $157,100.00. This position is eligible for annual bonus pay based on performance, per plan terms. Many factors are taken into consideration when determining compensation, such as experience, education, training, geography, etc. We comply with all minimum wage and overtime laws.

Ecolab strives to provide comprehensive and market-competitive benefits to meet the needs of our associates and their families. Click here to see our benefits. 

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