Senior Scientist, Bioanalysis

Job Description

General Summary:
Vertex Pharmaceuticals is seeking a highly skilled and motivated Senior Scientist in Bioanalysis to join our dynamic team. The successful candidate will play a pivotal role in designing, executing, and interpreting complex bioanalytical experiments to support our innovative small molecule research and development programs. This position requires a deep understanding of LC-MS and related sample preparation techniques, a strong ability to manage multiple projects, and a commitment to advancing scientific discovery in alignment with Vertex’s mission.

Key Duties and Responsibilities:

• Design and execute technically challenging LC-MS-based bioanalytical experiments to support small molecule drug discovery and development.

• Analyze and interpret complex, multidimensional data to generate clear hypotheses and guide experimental directions.

• Develop and optimize bioanalytical methods to address critical research questions.

• Manage multiple projects effectively, ensuring alignment with corporate goals and timelines.

• Conduct advanced troubleshooting and implement innovative solutions to experimental challenges.

• Stay abreast of relevant scientific literature and integrate new concepts and methodologies into research strategies.

• Collaborate with cross-functional teams to drive project success and contribute to the development of novel therapeutics.

• Prepare and review technical reports, publications, and regulatory documentation as required.

Knowledge & Skills:

• Strong expertise in bioanalytical techniques, including but not limited to LC-MS/MS, automation, and other relevant methodologies.

• Quantitative analysis and method development of small molecules.

• Proven ability to manage and prioritize multiple projects in a fast-paced environment.

• Excellent problem-solving skills and a track record of innovative method development.

• Strong communication and collaboration skills, with the ability to work effectively in a multidisciplinary team.

Education & Experience:

• Ph.D. in Biochemistry, Molecular Biology, Analytical Chemistry, or a related field with 2+ years of relevant post-doctoral experience; or

• Master’s degree with 5+ years of relevant experience; or

• Bachelor’s degree with 8+ years of relevant experience.

Pay Range:

Disclosure Statement:

Flex Designation:

Flex Eligibility Status:

In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.  

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Onsite

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [email protected]