Senior Scientist - Antibody Discovery, Sequencing & Epitope Strategy

Posted 25 Days Ago
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Cambridge, Cambridgeshire, England, GBR
In-Office
Senior level
Healthtech • Other • Software • Biotech
The Role
The Senior Scientist will design and execute antibody experiments, integrating sequencing data and understanding biological behavior, while partnering with engineering and data teams.
Summary Generated by Built In

For over 25 years, Abcam has been providing tools the scientific community needs to enable faster breakthroughs in critical areas like cancer, neurological disorders, infectious diseases, and metabolic disorders. 

At Abcam, our mission is to empower scientists globally, and we aim to be the most influential life sciences company in the world. 

We believe that to continue making progress, we need to work together, each bringing our own unique perspectives to make an impact on the world. This community needs people like you: dedicated, agile and above all audacious so we can truly drive science forward. 

We are seeking a Senior Scientist – Antibody Data & Epitope Strategy to join the Danaher Affinity Reagents Autonomous Laboratory (DARAL) at Abcam in Cambridge. In this role, you will Perform experimental antibody research and data generation within DARAL, with a focus on integrating sequencing, repertoire diversity, and epitopelevel insight to drive antibody and target strategy on challenging biology. This lab-based position reports to the Director of Production for the Danaher Affinity Reagents Autonomous Laboratory and is based in Cambridge, UK. 

 

In this role, you will have the opportunity to: 

  • Design and execute experiments to generate antibody sequence, repertoire, and epitopelevel data 

  • Integrate sequencing outputs with binding and functional data to understand antibody diversity and convergence 

  • Develop experimental strategies that link sequence space to biological behaviour across hard targets 

  • Use datadriven insight to inform antibody format choice, target prioritisation, and progression decisions within DARAL 

  • Partner with engineering, automation, and data teams to ensure sequencingenabled experiments are scalable and reusable 

 

The essential requirements of the job include: 

  • PhD (or equivalent) in a life sciences discipline, with 5+ years’ experience in antibody discovery, protein science, or related experimental fields 

  • Strong understanding of antibody sequence–structure–function relationships, including epitope recognition and biological context 

  • Handson experience generating or analysing antibody sequence or repertoire data 

  • Experience with experimental approaches to epitope characterisation (e.g. competition assays, mutagenesis, domain mapping, or binning strategies) 

  • Excellent communication skills, with the ability to explain scientific trade-offs and priorities to diverse stakeholders 

 

It would be a plus if you also possess previous experience in: 

  • Antibody repertoire sequencing, NGSenabled discovery, or diversity analysis 

  • Alternative antibody formats (e.g. VHHs, scFvs, engineered libraries) 

  • Relating sequence and epitope diversity to downstream reagent performance 

  • Working on hardtodrug or historically challenging targets (e.g. membrane proteins) 

  • Supporting higherthroughput or automationready antibody discovery workflows 

#LI-Onsite

Join our winning team today. Together, we’ll accelerate the real-life impact of tomorrow’s science and technology. We partner with customers across the globe to help them solve their most complex challenges, architecting solutions that bring the power of science to life.

For more information, visit www.danaher.com.

Skills Required

  • PhD (or equivalent) in a life sciences discipline
  • 5+ years' experience in antibody discovery or protein science
  • Strong understanding of antibody sequence-structure-function relationships
  • Hands-on experience generating or analysing antibody sequence data
  • Experience with experimental epitope characterisation approaches
  • Excellent communication skills for diverse stakeholders

Beckman Coulter Diagnostics Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Beckman Coulter Diagnostics and has not been reviewed or approved by Beckman Coulter Diagnostics.

  • Healthcare Strength Healthcare coverage is described as comprehensive, including medical, dental, vision, life and disability insurance, flexible spending accounts, and mental health support. Feedback suggests these offerings are a notable strength of the overall package.
  • Leave & Time Off Breadth Paid time off, paid holidays, sick days, and volunteer time are highlighted, with flexibility or remote arrangements available for some roles. Feedback suggests this breadth of time-off options contributes meaningfully to total rewards.
  • Parental & Family Support Paid parental leave is provided for birth, adoption, or foster placement with the ability to use time in flexible increments within the first year. Feedback suggests family-focused perks like adoption support add tangible value for caregivers.

Beckman Coulter Diagnostics Insights

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The Company
HQ: Brea, CA
10,526 Employees
Year Founded: 1935

What We Do

Beckman Coulter is committed to advancing healthcare for every person by applying the power of science, technology, and the passion and creativity of our teams to enhance the diagnostic laboratory’s role in improving healthcare outcomes. Our diagnostic systems are used in complex biomedical testing, and are found in hospitals, reference laboratories and physician office settings around the globe. Beckman Coulter offers a unique combination of people, processes and solutions designed to elevate the performance of clinical laboratories and healthcare networks. We do this by accelerating care with a menu that matters, bringing the benefit of automation to all, delivering greater insights through clinical informatics and unlocking hidden value through performance partnership. An operating company of Danaher Corporation since 2011, Beckman Coulter is headquartered in Brea, Calif., and has more than 11,000 global associates working diligently to make the world a healthier place.

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