AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.
Job DescriptionSenior Scientist 1, Bioassay Development, CMC Biologics, Analytical Research & Development, AbbVie Biotherapeutics Inc., South San Francisco, CA: Onsite (onsite 5 days per week).
Key Responsibilities
- Develop & optimize complex bioassays & target-binding potency assays critical for development of complex biotherapeutics.
- Collaborate with analytical teams to elucidate structure/function & interact cross-functionally with teams from Discovery, Chemistry Manufacturing & Controls (CMC), QC, QA to support drug development activities & IND submissions.
- Qualify/validate/transfer potency methods to external partners & author technical documents (e.g. test methods, protocols, & reports) to enable regulatory submissions).
- Develop new techniques, explore new approaches & technologies, perform troubleshooting & optimization experiments, & present your work to various cross-functional teams.
Education & Experience
Must possess a MS degree in biology, biochemistry, cell/molecular biology, or a related field & 1 year of academic research experience or industry work as a development scientist.
Of academic research experience &/or industry work experience required, must have 1 year:
- developing binding potency assays (ELISA, TR-FRET, Octet, flow cytometry, other cell-based formats) to characterize & test protein therapeutics (monoclonal antibodies, ADCs, &/or other biologic modalities);
- developing cell-based functional potency assays (cytotoxicity assays, reporter gene assays, proliferation assays, effector function activity assays (i.e. ADCC, CDC) to characterize & test protein therapeutics (monoclonal antibodies, ADCs, &/or other biologic modalities);
- performing cell-based target binding potency assays, noncell-based target binding potency assays, &/or functional potency assays to characterize drug mechanism of action;
- using GraphPad PRISM, PLA, Softmax Pro, or similar data analysis software;
- optimizing & troubleshooting potency assays to improve performance &/or resolve performance issues;
- working in a matrixed organization within a crossfunctional scientific environment within a (CMC) organization; &
- authoring technical reports, drafting SOPs, writing CMC sections of regulatory filings, & giving scientific presentations to peers & management.
Alternatively, would accept BS Degree in biology, biochemistry, cell/molecular biology, or a related field & 5 years academic research experience &/or industry work experience required as a development scientist.
Of work experience required, must have 5 years of academic research experience &/or industry work experience in each of (i) (ii), (iii), (iv), (v), (vi) & (vii).
Work experience may be gained concurrently. Will accept combination of education, training & work experience.
Additional InformationSalary Range: $143,067.06 - $162,000.00 per year.
Apply online at https://careers.abbvie.com/en or send resume to [email protected]. Refer to Req ID: REF49886M
---------------------------------------------------------------------------
We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees. This job is eligible to participate in our short-term and long-term incentive programs.
AbbVie is committed to operating with integrity, driving innovation, transforming lives, serving our community, and embracing diversity and inclusion. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html
US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:
https://www.abbvie.com/join-us/reasonable-accommodations.html
Skills Required
- Master of Science degree in biology, biochemistry, cell biology, molecular biology, or a related field, plus at least 1 year of academic research experience or industry experience as a development scientist
- Alternatively, Bachelor of Science degree in biology, biochemistry, cell biology, molecular biology, or a related field, plus at least 5 years of academic research experience or industry experience as a development scientist
- At least 1 year developing binding potency assays such as ELISA, TR-FRET, Octet, flow cytometry, or other cell-based formats for protein therapeutics; 5 years required under the BS alternative
- At least 1 year developing cell-based functional potency assays, including cytotoxicity, reporter gene, proliferation, ADCC, or CDC assays; 5 years required under the BS alternative
- At least 1 year performing cell-based, non-cell-based, or functional potency assays to characterize drug mechanisms of action; 5 years required under the BS alternative
- At least 1 year using GraphPad PRISM, PLA, SoftMax Pro, or similar data analysis software; 5 years required under the BS alternative
- At least 1 year optimizing and troubleshooting potency assays; 5 years required under the BS alternative
- At least 1 year working in a matrixed, cross-functional scientific environment within a CMC organization; 5 years required under the BS alternative
- At least 1 year authoring technical reports, drafting SOPs, writing CMC sections of regulatory filings, and presenting scientific work; 5 years required under the BS alternative
AbbVie Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about AbbVie and has not been reviewed or approved by AbbVie.
-
Retirement Support — Retirement programs are portrayed as a standout, with a dollar‑for‑dollar 401(k) match up to 6% and an additional annual company contribution based on age and service. Feedback suggests this materially boosts perceived total compensation for many U.S. employees.
-
Parental & Family Support — Paid parental and caregiver leave are emphasized, including up to 12 weeks of fully paid parental leave for all parents and 4 weeks of paid caregiver leave in the U.S. Feedback suggests these policies are a meaningful differentiator for employees balancing family needs.
-
Leave & Time Off Breadth — Time off is described as extensive, with tiered vacation that scales with tenure, 17 company holidays, and two paid volunteer days in the U.S. Feedback suggests the breadth of leave contributes notably to overall benefits satisfaction.
AbbVie Insights
What We Do
AbbVie is a global biopharmaceutical company focused on creating medicines and solutions that put impact first — for patients, communities, and our world. We aim to address complex health issues and enhance people's lives through our core therapeutic areas: immunology, oncology, neuroscience, eye care, aesthetics and other areas of unmet need.
