Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.
Job Summary
The Wainger Laboratory at Massachusetts General Hospital (MGH) is seeking a highly motivated, collaborative, and innovative Senior Scientist to lead high-impact translational research at the intersection of neurodegenerative diseases, stem cell biology, functional genomics, and computational biology.The successful candidate will leverage human postmortem tissue analyses, patient-derived induced pluripotent stem cell (iPSC) neuron models, and advanced bioinformatics/multi-omic pipelines to systematically discover, prioritize, validate, and develop novel therapeutic targets. This role offers an exceptional opportunity to work within a deeply translational environment closely aligned with the Healey Center for ALS at MGH, Broad Institute, and Harvard Medical School.
Independently carries out a broad range of technically advanced research activities and procedures; conceives of and designs experiments, evaluates conclusions, and has complete latitude to modify or devise methods and techniques as necessary to achieve desired results; may supervise technical and administrative elements of research unit.
Essential Functions
-Function as a skilled scientific specialist for the research unit or for a specific research project.
-Conducts broad range of experiments or computational analyses involving advanced technology/strategies; conceives of the objective of research studies and designs experimental protocols/computational analyses to achieve the objectives; generates, analyzes and evaluates experimental data; interprets the results of experiments/computational analyses.
-Writes and edits material for publication; may present papers or appear as principal or secondary author in publications.
-Provides direct supervision to technical and support personnel as assigned.
-Provides instruction in laboratory or computational techniques and methodology to students and postdoctoral fellows.
Qualifications
Education
Doctorate Related Field of Study required
Can this role accept experience in lieu of a degree?
No
Experience
Experience in an academic or laboratory research setting 5-7 years required.
Knowledge, Skills and Abilities
- Proficiency in supply chain and vendor management.
- Ability to identify problems and troubleshoot solutions.
- Well-versed in laboratory standards and practices.
- Good organizational skills, detail-oriented.
- Sound degree of computer literacy.
- Ability to methodically record data.
- Good interpersonal and communication skills.
- Broad knowledge of scientific principles, biological structures, and laboratory techniques.
Additional Job Details (if applicable)
$70,000 - $113,000.
Remote Type
Work Location
Scheduled Weekly Hours
Employee Type
Work Shift
EEO Statement:
At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
Skills Required
- Doctorate in a related field
- 5-7 years experience in an academic or laboratory research setting
- Proficiency in bioinformatics and multi-omic analysis pipelines
- Experience with iPSC-derived neuron models and human postmortem tissue analyses
- Well-versed in laboratory standards and practices
- Ability to design experiments and computational analyses, and interpret results
- Strong organizational skills, attention to detail, and methodical data recording
- Good interpersonal and communication skills, including writing/editing for publication
- Sound degree of computer literacy
- Proficiency in supply chain and vendor management
- Broad knowledge of scientific principles, biological structures, and laboratory techniques
What We Do
Mass General Brigham is an integrated academic health care system, uniting great minds to solve the hardest problems in medicine for our communities and the world. Mass General Brigham connects a full continuum of care across a system of academic medical centers, community and specialty hospitals, a health insurance plan, physician networks, community health centers, home care, and long-term care services. Mass General Brigham is a nonprofit organization that is committed to patient care, research, teaching, and service to the community. In addition, Mass General Brigham is one of the nation’s leading biomedical research organizations and a principal teaching affiliate of Harvard Medical School.
