About The Role
We are seeking a highly motivated and experienced Senior Research Scientist with strong expertise in bioanalytical mass spectrometry to join our Method Development team. The successful candidate will lead the development and optimization of regulatory-ready bioanalytical methods using liquid chromatography-mass spectrometry (LC-MS/MS) for a variety of therapeutic modalities, including small molecules, peptides, biologics, biomarkers, and oligonucleotides.
What You’ll Do Here
Develop and optimize robust bioanalytical methods using LC-MS/MS in compliance with regulatory standards.
Perform and oversee sample preparation, analysis, and data interpretation while meeting project timelines and quality expectations.
Investigate and resolve complex bioanalytical challenges through systematic troubleshooting, experimental design, and root-cause assessment.
Participate in client discussions and scientific meetings, communicating method development strategies, analytical results, and technical recommendations.
Prepare, review, and approve method development reports, SOPs, and other technical documentation as required.
Collaborate with validation and operational teams to support successful method transfer and implementation.
Stay current with advancements in LC-MS technologies and best practices to support continuous improvement.
Adhere to Health and Safety protocols, including personal protective practices and laboratory upkeep.
What You’ll Need to Succeed
Master’s or Ph.D. in Biochemistry, Chemistry, Analytical Chemistry, or a related discipline; a Bachelor’s degree with significant relevant experience may also be considered.
Typically 5-8+ years of relevant experience in LC-MS/MS bioanalysis, with demonstrated experience independently leading bioanalytical method development projects.
Experience in sample preparation techniques appropriate to the analyte type (e.g., protein precipitation, solid-phase extraction, immunoaffinity-based approaches, enzymatic digestion).
Strong scientific writing, communication, and presentation skills, with the ability to effectively communicate complex technical concepts to both scientific and non-scientific stakeholders.
Altasciences strives to provide a French work environment for its employees in Quebec. Altasciences has taken all reasonable measures to avoid imposing the above language requirement. This requirement is essential for the position of Senior Research Scientist, Method development (LCMS) in particular, but without limitation, for the following reason(s):
The requirement to have study protocols read and documented in English as required by industry regulatory agencies
What We Offer
Altasciences offers a wide variety of benefits to help our employees live healthy and fulfilling lives both at and outside of work.
Altasciences’ Benefits Package Includes:
Health/Dental/Vision Insurance Plans
401(k)/RRSP with Employer Match
Paid Vacation and Holidays
Paid Sick and Bereavement Leave
Employee Assistance & Telehealth Program
Altasciences’ Incentive Programs Include:
Training & Development Programs
Employee Referral Bonus Program
Annual Performance Reviews
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Skills Required
- Master’s or Ph.D. in Biochemistry, Chemistry, Analytical Chemistry, or a related discipline
- Bachelor’s degree with significant relevant experience may be considered
- 5–8+ years of relevant experience in LC-MS/MS bioanalysis
- Experience independently leading bioanalytical method development projects
- Experience with sample preparation techniques including protein precipitation, solid-phase extraction, immunoaffinity-based approaches, and enzymatic digestion
- Strong scientific writing, communication, and presentation skills
- Ability to communicate complex technical concepts to scientific and non-scientific stakeholders
- Ability to read and document study protocols in English
What We Do
Outsourcing made easy with a one-stop solution to early-phase drug development. We are an integrated drug development solution company, offering pharmaceutical and biotechnology companies a proven, flexible approach that removes the need for multiple service providers during the early stages of drug development. Whether for one study or an end-to-end program, we help you reach critical decision-making milestones sooner by improving speed and ease from lead candidate selection to clinical proof of concept, and beyond. When partnering with Altasciences, you can experience up to 40% in time savings thanks to our integrated, one-stop solution offering. We strive to create a true partnership with our clients, our partners, and our colleagues that enables a mutually supporting relationship built on a combination of excellent science and solid communication. Helping sponsors get better drugs to the people who need them, faster, for over 25 years. Our full-service offering is always tailored to your specific research needs: - Preclinical research - Clinical pharmacology - Drug formulation - Manufacturing and analytical services - Bioanalysis - Program management - Medical writing - Biostatics - Data management - And so much more!
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