Dyne Therapeutics is a clinical-stage muscle disease company focused on advancing innovative life-transforming therapeutics for people living with genetically driven diseases. With its proprietary FORCE™ platform, Dyne is developing modern oligonucleotide therapeutics that are designed to overcome limitations in delivery to muscle tissue. Dyne has a broad pipeline for serious muscle diseases, including clinical programs for myotonic dystrophy type 1 (DM1) and Duchenne muscular dystrophy (DMD), and a preclinical program for facioscapulohumeral muscular dystrophy (FSHD). For more information, please visit https://www.dyne-tx.com/, and follow us on X, LinkedIn and Facebook.
Role Summary:
We are seeking a highly motivated individual to join the Dyne Therapeutics Histology and Microscopy team group located in Waltham, MA. The successful candidate will work in a team-oriented environment on multiple projects. The candidate will be working in a preclinical histology laboratory with a focus on non-human tissues and cells. They will be involved in both routine and specialized histology techniques utilizing paraffin, frozen and plastic embedding mediums. In addition, the individual should be detail oriented as they will be involved in reagent preparation, documentation and troubleshooting. The right candidate will become an integral part of a fast-paced histology lab supporting a dynamic range of research programs at Dyne.
This role is based in Waltham, MA without the possibility of being a remote role. Applicants must be able to relocate to the area.
Primary Responsibilities Include:
- Paraffin, plastic and frozen processing and microtomy
- Routine and histochemical staining both automated and manual
- Develop and troubleshoot new histochemical assays as needed
- Comply with written protocols, documentation requirements and safety policies
- Use and maintain histology lab equipment
- Prepare high quality images to support scientific presentations and publications
Education and Skills Requirements:
- Minimum of a bachelor’s degree in life science or related discipline is required
- Minimum of 4 years of experience in a histology lab, working with both human and non-human sourced materials
- Histotechnician or Histotechnologist Certification
- Proficiency with tissue collection/necropsy is desirable
- Knowledge and experience processing methyl methacrylate is preferred
- Image analysis and immunohistochemistry experience is a plus
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The statements contained herein reflect general details as necessary to describe the principles functions for this job, the level of knowledge and skill typically required, and the scope of responsibility, but should not be considered an all-inclusive listing of work requirements. Individuals may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise balance workload.
This description is not intended to be constructed as an exhaustive list of duties, responsibilities, or requirements for the position. This position may change or assume additional duties at any time. The employee may be requested to perform different or additional duties as assigned. All Employees are expected to adhere to all company policies and act as a role model for company values.
Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.
What We Do
Dyne Therapeutics is a clinical-stage muscle disease company focused on advancing innovative life-transforming therapeutics for people living with genetically driven diseases. With its proprietary FORCE™ platform, Dyne is developing modern oligonucleotide therapeutics that are designed to overcome limitations in delivery to muscle tissue seen with other approaches. Dyne has a broad portfolio of programs for serious muscle diseases, including candidates for myotonic dystrophy type 1 (DM1), Duchenne muscular dystrophy (DMD) and facioscapulohumeral muscular dystrophy (FSHD). For more information, please visit https://www.dyne-tx.com.
