Senior Research Associate, Genome Engineering

Responsibilities

• Execute in vitro experiments to characterize and cultivate hPSCs and their derivatives.
• Collaborate cross-functionally with stakeholders in other platform and program teams to characterize engineered or reprogrammed cell lines.
• Perform DNA/RNA-based, cell-based, flow cytometric, immunofluorescence and other protein-based analytical assays as required.
• Analyze and document experimental data in electronic laboratory notebooks in a timely and accurate manner in accordance with the company quality management system.
• Be responsible for data generation, collection, interpretation and communication of results.
• Prepare and follow standard operating procedures, batch records and other process documentation.
• Attend and present scientific data to colleagues at internal meetings.

Minimum Requirements

• B.S. or M.Sc. in cell biology, molecular biology, genetics or related discipline, with a minimum of 5 years (B.S.) or 3 years (M.Sc.) laboratory research or industry experience.
• Strong experience with human pluripotent stem cell or mammalian cell culture.
• Experience with cell characterization technologies including PCR, DNA sequencing, qPCR, flow cytometry and immunofluorescence.
• Experience with gene editing and iPSC reprogramming technologies is advantageous.
• Experience with cell transfection techniques is preferred.
• Knowledge of lineage-specific differentiation of human pluripotent stem cells is advantageous.
• Experience with DNA design software is preferred.
• Excellent analytical, problem solving and organizational skills.
• Strong written and verbal communications skills.