Sr Research Associate, Biotherapeutics
About the role
We are seeking an enthusiastic, and highly motivated scientist to join our team. With a background in conjugation, purification and analytical characterization of antibody drug conjugates (ADCs), and a track record of contributing to multidisciplinary drug discovery teams, this position will play a critical role in driving Treeline’s portfolio forward. You will also play a key role in developing the next generation of ADCs using bioconjugation, biochemistry, analytical chemistry techniques and various state-of-the-art scientific approaches. You will closely collaborate with other biochemists, medicinal chemists, biologists, and pharmacologists to enable forward progress of drug discovery programs.
Responsibilities
- Perform, develop and optimize conjugation methods to generate high quality ADCs to support drug discovery campaigns.
- Conduct routine purification and analytical characterization of ADCs.
- Evaluate physicochemical properties, stability and developability of lead ADC candidates.
- Design and conduct well controlled high-quality experiments to answer key scientific questions.
- Contribute to evaluation and development of new approaches and technologies within the bioconjugation group.
- Closely collaborate with medicinal chemistry, protein science and biology teams.
- Maintain an electronic lab notebook in compliance with company policies.
- Help establish the bioconjugation group and contribute to building a culture that embraces continuous learning and improvement.
Qualifications
- BS or MS in Biochemistry, Chemistry, or related discipline with at least two years of experience in antibody conjugation.
- Experience with purification and analytical characterization of ADCs using AKTA, UF/DF, UV-Vis, LC-MS, SEC, SDS-Page is required.
- Strong written and oral communication skills, excellent interpersonal skills, with demonstrated ability to work collaboratively on cross-functional, multidisciplinary teams.
Recruitment fraud statement
Please be aware of recruitment fraud and related job scams, where scammers present themselves as recruiters but are seeking to steal money or personal information. Keep the following in mind to protect yourself:
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- You can find more information about job scams at consumer.ftc.gov/articles/job-scams.
- To report job scams, head to ReportFraud.ftc.gov.
The Human Resources team manages the recruitment and employment process for Treeline Biosciences. To protect the interests of all parties involved, Treeline Biosciences will only accept resumes from a recruiter if an executed search agreement directed to the particular position or positions is in place at the start of the recruitment effort. Unsolicited resumes sent to Treeline Biosciences from recruiters do not constitute any type of relationship between the recruiter and Treeline Biosciences and do not obligate Treeline Biosciences in any way to pay fees should we hire from those resumes. Recruiters are requested not to contact or present candidates directly to our hiring manager or employees.
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We aspire to build transformative precision medicines for patients with cancer and other serious conditions
