Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. From our three R&D sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting-edge therapeutics for patients worldwide.
Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel). Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma.
Legend Biotech is seeking a Senior Research Associate/Associate Scientist (Contractor) as part of the Early Drug Development team based in Somerset, NJ.
Role Overview
We are seeking a highly motivated and detail-oriented Bioassay research scientist to join our Bioanalytical team. The ideal candidate will bring technical expertise in molecular assays (qPCR/ddPCR), multi-parameter flow cytometry and contribute to the daily operations of the lab supporting both clinical and preclinical research. This role requires strong organizational skills, the ability to collaborate effectively with cross-functional teams, and a background in biology or a related field. The successful candidate will play a critical role in ensuring the accuracy, reproducibility, and integrity of experimental data.
Key Responsibilities
- Molecular & Flow cytometry assays.
- Collaborate within a dynamic, cross-functional team to perform molecular and flow cytometry-based assays for the characterization of clinical, preclinical, and animal samples.
- Execute flow experiments following the best practices of the field.
- Perform quantitative PCR (qPCR) and ddPCR assays for gene expression analysis and biomarker quantification in clinical and preclinical samples.
- Assist in development, execution, and interpretation of new assay methods.
- Maintain thorough and accurate records, including laboratory notebooks, ELNs (Electronic Laboratory Notebooks), instrument logs, maintenance records, and troubleshooting documentation.
- Sample & Inventory Management.
- Support lab operations including ordering and inventory management of consumables, reagents, and antibodies.
- Provide weekend and shift coverage as needed.
- Train on and utilize LabVantage LIMS for biosample tracking, management, and test setup.
- Coordinate with warehouse teams for incoming and outgoing sample shipments (Legend shipments) and ensure proper documentation.
- Maintain an organized inventory of lab supplies, reagents, and chemicals.
- Ensure efficient processing of preclinical, translational, and bioanalytical samples.
Qualifications
- BS in Biology or related field with 2+ years of relevant experience, or MS with 1+ years of experience in a pharmaceutical or biotech setting.
- Hands-on experience with molecular assays, flow cytometry, bioassays, immunoassays, and molecular testing platforms.
- Knowledge of preclinical development and patient sample analysis.
- Experience with LIMS (LabVantage preferred), IT networks, and database systems is a plus.
- Proven experience in lab inventory, equipment maintenance, and vendor coordination.
- Strong technical proficiency in flow cytometry, molecular bioassays, and diagnostics.
- Excellent organizational and data documentation skills.
- Proficient with various flow cytometry instruments (e.g., BD, Cytek, Beckman Coulter).
- Familiarity with analytical software such as SpectroFlo, and FlowJo.
- Experience with ELISA and PCR/qPCR/ddPCR skills.
- High parameter flow skills are plus.
- Team-oriented, proactive, and adaptable in a dynamic lab environment.
- Schedule: 8-hour day shift, Monday to Friday (Saturday coverage may be required.
#Li-JR1
#Li-Contract
Benefits
We are committed to creating a workplace where employees can thrive - both professionally and personally. To attract and retain top talent in a highly competitive industry, we offer a best-in-class benefits package that supports well-being, financial stability, and long-term career growth. Our offerings are designed to meet the diverse needs of our team members and their families, ensuring they feel valued and supported every step of the way. Highlights include medical, dental, and vision insurance as well as a 401(k)-retirement plan with company match that vest fully on day one. Equity and stock options are available to employees in eligible roles, we offer eight weeks of paid parental leave after just three months of employment, and a paid time off policy that includes 15 vacation days, 5 personal days, 5 sick days, 11 U.S. national holidays, and 3 floating holidays. Additional benefits include flexible spending and health savings accounts, life and AD&D insurance, short- and long-term disability coverage, legal assistance, and supplemental plans such as pet, critical illness, accident, and hospital indemnity insurance. We also provide commuter benefits, family planning and care resources, well-being initiatives, and peer-to-peer recognition programs - demonstrating our ongoing commitment to building a culture where our people feel empowered, supported, and inspired to do their best work.
EEO Statement
Legend Biotech is a proud equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is Legend’s policy to ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protected by applicable law.
Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company. Legend may adjust base salary or other discretionary compensation at any time based on individual, team, performance, or market conditions.
Legend Biotech maintains a drug-free workplace.
Top Skills
What We Do
Legend Biotech is a global, commercial-stage biotechnology company developing and manufacturing novel therapies. We explore and apply innovative technologies to deliver cutting-edge options for patients around the world.
Our corporate headquarters is located in Somerset, NJ, and our manufacturing footprint includes facilities in the United States, China and the Belgium.
