Senior Principal Software Engineer, Digital Product R&D

Posted Yesterday
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Irvine, CA, USA
In-Office
139K-196K Annually
Senior level
Healthtech • Pharmaceutical
The Role
Design, develop, test, debug, and deploy scalable cloud-native software in a regulated medical-device environment. Lead architecture, coding, prototyping, APIs, microservices, distributed systems, and full-stack development while applying Generative AI, LLMs, RAG, and AI agents. Provide technical leadership through code reviews, design discussions, mentoring, and cross-functional collaboration with product, clinical, quality, systems, and cybersecurity teams.
Summary Generated by Built In

Innovation starts from the heart. Our Advanced Innovation & Technology (AI&T) teams harness the imagination, courage, and resourcefulness to think beyond what’s currently possible, and create solutions for patients many years into the future. If you’re an early-stage innovator, then Edwards AI&T team is the place for you to take the next steps in your career. We’ll give you the tools and resources you need to create groundbreaking innovations that shape the future of structural heart technology.


How you will make an impact:


Design, develop, test, and deliver scalable, high-quality software solutions in a regulated medical-device environment. This is a hands-on Senior Principal Engineer role requiring strong software development skills, cloud experience, and proficiency with modern Generative AI tools. The individual will personally contribute to architecture, coding, prototyping, debugging, testing, and deployment while providing technical leadership and mentoring to the broader engineering team.


  • Personally design, develop, prototype, test, debug, and deploy production-quality software across the full software development lifecycle.
  • Lead the design and development of scalable cloud-native software applications, services, APIs, and data solutions.
  • Translate complex system and product requirements into practical technical designs and software architecture, and personally drive implementation through delivery.
  • Leverage Generative AI and AI-assisted software development tools to accelerate coding, testing, debugging, documentation, code analysis, code review, and software design.
  • Prototype and develop solutions using emerging GenAI technologies, including Large Language Models (LLMs), AI agents, Retrieval-Augmented Generation (RAG), and related technologies where appropriate.
  • Evaluate and resolve performance issues and software defects through hands-on root cause analysis, debugging, and implementation of efficient solutions.
  • Provide technical leadership through code reviews, architectural discussions, design reviews, and mentoring while maintaining significant individual technical contribution.
  • Collaborate with product, systems, clinical, quality, cybersecurity, and other cross-functional teams to deliver software that meets product, regulatory, quality, and customer requirements.
  • Drive continuous improvement in software engineering practices, development productivity, automation, and application of AI-assisted development technologies.

This is a fully on-site role based at our corporate headquarters in Irvine, CA.


What you'll need (Required):


  • Bachelor's Degree in Computer Science or related field with 10 years of experience relevant experience or equivalent work experience based on Edwards criteria -OR- Master's Degree or equivalent in Computer Science or related field, with 8 years of experience relevant experience or equivalent work experience based on Edwards criteria
  • Strong hands-on software development experience with demonstrated ability to personally write, review, debug, test, and deploy production-quality software.
  • Strong experience with C#, .NET, TypeScript/JavaScript, Angular or comparable modern web frameworks, RESTful APIs, SQL, Git, CI/CD, and automated testing.
  • Experience designing and implementing modern software architectures, including APIs, microservices, distributed systems, and cloud-native applications.
  • Strong hands-on experience developing cloud-native applications and services using Microsoft Azure, AWS, Google Cloud, or equivalent cloud platforms.
  • Experience with cloud APIs, containers, CI/CD, observability, security, scalability, and distributed systems. 
  • Demonstrated proficiency using Generative AI and AI-assisted software development tools such as GitHub Copilot, Cursor, Claude, ChatGPT, Gemini, or equivalent technologies.
  • Practical experience applying GenAI to software engineering activities including code generation, refactoring, debugging, test generation, documentation, code review, and software design.
  • Experience developing applications or prototypes using LLMs, RAG, AI agents, or other GenAI technologies is highly desirable.

 What else we look for (Preferred):


  • Experience developing software for medical devices, healthcare, or other regulated products.
  • Understanding of software lifecycle processes, risk management, cybersecurity, verification/validation, and regulatory requirements applicable to regulated products. 
  • Strong technical communication and collaboration skills with the ability to influence architecture and engineering decisions across multidisciplinary teams.
  • Demonstrated ability to mentor other engineers while maintaining significant individual technical contribution.
  • Strong background in designing and implementing applications using current protocols and standards
  • Extensive experience analyzing, optimizing, and maintaining already deployed applications
  • Extensive experience with full stack development on Microsoft .NET platform specifically Angular.js, TypeScript, REST. – Are there any other applications/tools/technologies you’d like to include? Nope – Cordella is a great model for what we want to do with the THV projects
  • Strong understanding of ASP.NET/ MVC/WEBAPI/WCF, and IIS Architecture
  • Comfortable with varying tools and technologies including C#, SQL Server, Web Services, SOA architecture, JSON/XML/XSL, JavaScript, CSS, jQuery, Visual Studio, Assembla / Git, Azure DevOps
  • Knowledge and understanding of system flow charts, data processing concepts, and telecommunications principles
  • Adhere to all company rules and requirements (e.g., pandemic protocols, Environmental Health & Safety rules) and take adequate control measures in preventing injuries to themselves and others as well as to the protection of environment and prevention of pollution under their span of influence/control

Aligning our overall business objectives with performance, we offer competitive salaries, performance-based incentives, and a wide variety of benefits programs to address the diverse individual needs of our employees and their families.
For California, the base pay range for this position is $139,000 - $196,000 (highly experienced).
The pay for the successful candidate will depend on various factors (e.g., qualifications, education, prior experience).  Applications will be accepted while this position is posted on our Careers website.  


Edwards is an Equal Opportunity/Affirmative Action employer including protected Veterans and individuals with disabilities.

Skills Required

  • Bachelor's degree in Computer Science or related field plus 10 years of relevant experience, or equivalent experience
  • Alternatively, master's degree or equivalent in Computer Science or related field plus 8 years of relevant experience
  • Hands-on experience personally writing, reviewing, debugging, testing, and deploying production-quality software
  • Experience with C#, .NET, TypeScript or JavaScript, Angular or comparable modern web frameworks, RESTful APIs, SQL, Git, CI/CD, and automated testing
  • Experience designing and implementing APIs, microservices, distributed systems, and cloud-native applications
  • Hands-on experience developing cloud-native applications using Microsoft Azure, AWS, Google Cloud, or equivalent platforms
  • Experience with cloud APIs, containers, CI/CD, observability, security, scalability, and distributed systems
  • Proficiency using Generative AI and AI-assisted software development tools
  • Practical experience applying Generative AI to code generation, refactoring, debugging, testing, documentation, code review, and software design
  • Experience developing applications or prototypes using LLMs, RAG, AI agents, or related Generative AI technologies
  • Experience developing software for medical devices, healthcare, or other regulated products
  • Understanding of software lifecycle processes, risk management, cybersecurity, verification and validation, and regulatory requirements
  • Strong technical communication, collaboration, architecture influence, and mentoring skills
  • Experience with current application protocols and standards
  • Experience analyzing, optimizing, and maintaining deployed applications
  • Full-stack Microsoft .NET development experience with Angular, TypeScript, and REST
  • Knowledge of ASP.NET, MVC, Web API, WCF, and IIS architecture
  • Experience with SQL Server, web services, SOA, JSON, XML, XSL, JavaScript, CSS, jQuery, Visual Studio, Assembla, and Azure DevOps
  • Knowledge of system flow charts, data processing concepts, and telecommunications principles

Edwards Lifesciences Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Edwards Lifesciences and has not been reviewed or approved by Edwards Lifesciences.

  • Healthcare Strength — Health coverage is considered strong, with multiple plan choices, HSA options, and fertility support, and the company highlights holistic well‑being programs.
  • Retirement Support — A company 401(k) match and well‑regarded retirement offerings add clear long‑term value to total compensation.
  • Equity Value & Accessibility — An Employee Stock Purchase Plan with a discount and look‑back feature makes equity ownership accessible and enhances the total rewards package.

Edwards Lifesciences Insights

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The Company
HQ: Irvine, CA
13,687 Employees
Year Founded: 1958

What We Do

Edwards Lifesciences (NYSE: EW), is the global leader in patient-focused medical innovations for structural heart disease, as well as critical care and surgical monitoring. We thrive on discovery and expanding the boundaries of medical technology, serving patients in 100+ countries, with the help of our employees in areas including Clinical Affairs, Quality Engineering, Research & Development, Regulatory Affairs, Sales & Marketing, corporate functions and more. Our roots date back to 1958 when Miles Lowell Edwards, a retired engineer with a background in hydraulics and fuel pump operations, set out to build the first artificial heart. Edwards believed the heart could be mechanized and was encouraged by Dr. Albert Starr to focus on developing an artificial heart valve. After just two years, the first Starr-Edwards mitral valve was developed and successfully placed in a patient. This innovation spawned Edwards Laboratories. Miles’ fascination with healing the heart and helping patients with heart disease stemmed from his own experience with rheumatic fever as a teenager and continues to fuel our patient-first culture today. Today, we are as passionate about providing innovative solutions for people fighting cardiovascular disease as we have ever been. It's our Credo. It takes integrity, collaboration, innovation, and focus. We are leaders in the design and manufacture of tissue replacement heart valves and repair products as well as advanced hemodynamic monitoring. We partner with physicians to innovate products designed to help patients live longer, healthier, and more productive lives. Our work is both rewarding and a privilege. The importance of what we do defines our approach. We work together to create an environment where ideas can flourish and we provide our people with the resources, expertise and support to bring those ideas to life. For our legal terms and trademarks, please visit: https://www.edwards.com/legal/legal-terms

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