Location: This position may be performed remotely but requires flexibility and a willingness to travel as needed.
Position Summary
Praxis is seeking a strategic, highly collaborative Senior Product Manager to help shape and execute commercialization strategy for our growing portfolio of therapies focused on central nervous system disorders. This role sits at the intersection of science, customer insight, and business strategy, helping translate complex clinical innovation into meaningful impact for patients, caregivers, and healthcare providers.
This is a high-ownership role for someone who thrives in ambiguity, moves with urgency, and knows how to align teams around clear priorities and outcomes. You will lead cross-functional initiatives spanning product strategy, launch readiness, market development, messaging, customer engagement, and competitive positioning. You will be expected to think beyond tactical execution — identifying opportunities, challenging assumptions, and helping shape commercial direction in a fast-moving biotech environment.
The right person combines strategic thinking with operational excellence. You are intellectually curious, action-oriented, and trusted by cross-functional partners because you bring clarity, accountability, and sound judgment. Most importantly, you are motivated by the opportunity to help deliver transformative therapies to patients with significant unmet needs.
Primary Responsibilities
- Lead development and execution of integrated product and commercialization strategies aligned to corporate and portfolio objectives
- Drive cross-functional alignment across Commercial, Medical Affairs, Market Access, Regulatory, Clinical, and Corporate Communications teams to support launch readiness and ongoing product strategy
- Translate scientific and clinical data into differentiated product positioning, messaging, and customer engagement strategies
- Partner with market research and analytics teams to generate actionable insights from customer feedback, market dynamics, competitive intelligence, and performance metrics
- Lead development of disease education, promotional, and non-promotional initiatives in partnership with agency and internal stakeholders
- Identify strategic risks, gaps, and opportunities proactively, helping teams make informed business tradeoff decisions
- Manage complex initiatives across multiple stakeholders while ensuring speed, quality, accountability, and compliance
- Contribute to long-range planning, portfolio strategy discussions, and commercialization readiness activities
- Serve as a collaborative leader and trusted thought partner who elevates cross-functional execution and organizational effectiveness
Qualifications and Key Success Factors
- Bachelor’s degree required; advanced degree preferred
- Demonstrated experience leading product strategy, commercialization, brand management, or launch initiatives within biotech, pharmaceutical, or healthcare environments
- Strong ability to synthesize scientific, customer, and market insights into clear strategic direction and actionable plans
- Experience influencing cross-functional stakeholders and driving alignment in complex, matrixed environments
- Excellent strategic thinking, communication, and presentation skills
- Strong project leadership and organizational skills with ability to manage multiple priorities simultaneously
- Comfortable operating in fast-paced, evolving organizations with high accountability and autonomy
- Demonstrated ability to navigate ambiguity, challenge assumptions constructively, and drive results through influence
- High ownership mindset with strong business judgment and bias toward action
- Experience in CNS, rare disease, specialty therapeutics, or launch environments is a plus
The physical and mental requirements of our roles include but are not limited to regular use of a computer, devices or other office equipment, clear communication, and occasional movement. You'll need comfort with screen work, basic hand coordination, and focus. Reasonable accommodations may be made to enable individuals with disabilities to perform these functions.
Compensation & Benefits
At Praxis, we believe that taking care of our people (and their people) is important, so we provide a world class benefits package to help you thrive. This includes 99% of the premium paid for medical, dental and vision plans. We also provide company-paid life insurance, AD&D, disability benefits, and voluntary plans to personalize your coverage. Thinking about the future? We match dollar-for-dollar up to 6% on eligible 401(k) contributions and sweeten the deal with long-term stock incentives and ESPP. We provide a discretionary quarterly bonus, an extremely flexible wellness benefit, generous PTO, paid holidays and company-wide shutdowns. Not to mention, you'll also be joining a phenomenal crew of colleagues who are smart, engaged and inspiring. We aim high, collaborate hard, and produce results. Let’s achieve the impossible together!
Company Overview
Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance. At Praxis we share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high impact medicines for patients and families affected by and living with complex brain disorders. Our core Values of Trust, Ownership, Curiosity and Results are foundational to every aspect of our business and are exemplified by each and every one of our team members.
Diversity, Equity & Inclusion
Guided by our core values, at Praxis Precision Medicines, Inc. we continue to DARE FOR MORE® to advance, promote, and champion diversity, equity, and inclusion by encouraging individuals to bring their authentic selves and perspectives to work each day. We are an equal opportunity employer and committed to providing opportunities to all qualified applicants without regard to race, religious creed, color, gender identity or expression, age, national origin, sexual orientation, disability, genetics, military service and veteran status, or any other characteristic protected by federal, state, or local laws.
Attention: Job Scam Alert
Praxis has recently become aware of fraudulent job recruitment postings from individuals claiming to represent Praxis. These postings seek financial information in connection with fraudulent opportunities for employment. If you suspect any fraudulent activity or misrepresentation in connection with a Praxis job opportunity, please report it to [email protected].
Praxis does not accept unsolicited submissions from recruitment agencies for open positions. We ask all recruitment agencies to refrain from contacting any Praxis employee regarding any position. All unsolicited resumes submitted by recruitment agencies to any Praxis employee in any form or method will be deemed to be the property of Praxis, and Praxis explicitly reserves the right to hire those candidate(s) without any financial obligation to the recruitment agency.
Skills Required
- Bachelor's degree required; advanced degree preferred
- Demonstrated experience leading product strategy in biotech, pharmaceutical, or healthcare
- Experience influencing cross-functional stakeholders
- Excellent strategic thinking and communication skills
- Strong project leadership and organizational skills
- Experience in CNS, rare disease, specialty therapeutics, or launch environments
What We Do
Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance. Praxis is applying insights into the genetic mutations that drive excitation-inhibition imbalance in diseases to select biological targets for rare and more prevalent neurological disorders. We share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high impact medicines for patients and families affected by and living with complex brain disorders. Praxis is applying genetic insights to the discovery and development of therapies for rare and more prevalent neurological disorders through our proprietary small molecule platform, Cerebrum™, and antisense oligonucleotide (ASO) platform, Solidus™, using our understanding of shared biological targets and circuits in the brain.
