Our Global Cyber Defense team is responsible for safeguarding Pfizer's digital assets and infrastructure through proactive threat detection, response, and risk mitigation across on-premises, cloud, and hybrid environments.
The Senior Manager, Threat Remediation is responsible for owning and driving the end‑to‑end remediation of cybersecurity threats across the enterprise. This role sits at the intersection of threat detection, incident response, vulnerability management, offensive security and technology risk, ensuring that identified threats are prioritized, mitigated, and resolved in a timely, risk‑based, and compliant manner.
This role will work closely with the SOC, Cloud Services, Infrastructure, End User Computing, Engineering, GRC, Legal, Privacy, and Business stakeholders to reduce cyber risk and improve the organization's overall security posture.
ROLE RESPONSIBILITIES
- Own the threat remediation lifecycle, from intake of identified threats (incidents, alerts, vulnerabilities, control gaps) through containment, mitigation, and closure.
- Translate threat intelligence, SOC findings, red team results, penetration tests, and vulnerability scans into actionable remediation plans.
- Ensure remediation actions are risk‑based, prioritized, and aligned with business impact, regulatory exposure, and threat severity.
- Partner with Incident Response and SOC teams during active incidents to ensure effective containment and eradication strategies.
- Lead post‑incident remediation efforts, ensuring root cause analysis (RCA) is completed and systemic issues are addressed.
- Track and validate completion of corrective and preventive actions (CAPAs) resulting from incidents.
- Work with IT, engineering, and application owners to resolve vulnerabilities while respecting validated system change controls.
- Ensure compensating controls are documented and approved where remediation is constrained due to regulatory or operational limitations.
- Define and report on remediation KPIs and KRIs (e.g., mean time to remediate, overdue critical findings, repeat issues).
- Provide executive‑level reporting on remediation status, risk reduction, and systemic weaknesses.
- Support internal and external audits, regulatory inspections, and security assessments by demonstrating effective remediation governance.
- Partner with detection, threat intelligence, and vulnerability teams to close gaps between detection and remediation.
- Contribute to long‑term cyber defense strategy, including roadmap planning and technology selection.
BASIC QUALIFICATIONS
- Bachelor's degree in Computer Science, Information Security, Engineering, or a related technical discipline, or equivalent experience.
- 7+ years of experience in cybersecurity, with hands-on involvement in remediation, vulnerability management, security engineering, or incident response.
- Strong understanding of:
- Threat actor tactics, techniques, and procedures (MITRE ATT&CK)
- Incident response and containment strategies
- Vulnerability management and remediation workflows
- Cloud security (AWS, Azure, GCP)
- Endpoint, network, identity, and application security
- Familiarity with SOC tooling (SIEM, SOAR, EDR/XDR), vulnerability scanners, and ticketing/workflow systems.
- Demonstrated experience in an agile work environment possessing qualities such as a collaborative mindset, adaptability to change, and a proactive problem-solving approach.
- Leadership experience managing or mentoring analysts and engineers.
PREFERRED QUALIFICATIONS
- Working knowledge of GxP, FDA 21 CFR Part 11, EMA, HIPAA, GDPR, and other relevant regulations.
- Familiarity with security frameworks, risk management practices, and regulatory expectations relevant to pharmaceutical or life sciences organizations.
- Professional certifications such as CISSP, CISM, GIAC, or equivalent credentials related to security operations or risk management.
Please apply by sending your CV and a motivational letter in English.
Work Location Assignment: Hybrid
Purpose
Breakthroughs that change patients' lives... At Pfizer we are a patient centric company, guided by our four values: courage, joy, equity and excellence. Our breakthrough culture lends itself to our dedication to transforming millions of lives.
Digital Transformation Strategy
One bold way we are achieving our purpose is through our company wide digital transformation strategy. We are leading the way in adopting new data, modelling and automated solutions to further digitize and accelerate drug discovery and development with the aim of enhancing health outcomes and the patient experience.
Flexibility
We aim to create a trusting, flexible workplace culture which encourages employees to achieve work life harmony, attracts talent and enables everyone to be their best working self. Let's start the conversation!
Equal Employment Opportunity
We believe that a diverse and inclusive workforce is crucial to building a successful business. As an employer, Pfizer is committed to celebrating this, in all its forms - allowing for us to be as diverse as the patients and communities we serve. Together, we continue to build a culture that encourages, supports and empowers our employees.
Disability Inclusion
Our mission is unleashing the power of all our people and we are proud to be a disability inclusive employer, ensuring equal employment opportunities for all candidates. We encourage you to put your best self forward with the knowledge and trust that we will make any reasonable adjustments to support your application and future career. Your journey with Pfizer starts here!
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email [email protected]. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers .
Information & Business Tech
Skills Required
- Bachelor's degree in Computer Science, Information Security, Engineering, or related technical discipline, or equivalent experience
- 7+ years of experience in cybersecurity, remediation, vulnerability management, security engineering, or incident response
- Strong understanding of MITRE ATT&CK (threat actor tactics, techniques, and procedures)
- Strong understanding of incident response and containment strategies
- Strong understanding of vulnerability management and remediation workflows
- Cloud security experience (AWS, Azure, GCP)
- Experience with endpoint, network, identity, and application security
- Familiarity with SOC tooling (SIEM, SOAR, EDR/XDR)
- Familiarity with vulnerability scanners and ticketing/workflow systems
- Demonstrated experience in an agile work environment and proactive problem-solving mindset
- Leadership experience managing or mentoring analysts and engineers
- Working knowledge of GxP, FDA 21 CFR Part 11, EMA, HIPAA, GDPR, and other relevant regulations
- Familiarity with security frameworks, risk management practices, and regulatory expectations for life sciences
- Professional certifications such as CISSP, CISM, GIAC, or equivalent
Pfizer Compensation & Benefits Highlights
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Healthcare Strength — Health coverage includes comprehensive medical with robust mental‑health networks, plus dental and vision options, and coverage for infertility/family‑building and transgender‑affirming care. Recent U.S. summaries name mental‑health partners and outline multiple plan choices.
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Retirement Support — The retirement program provides a 401(k) with company match plus an additional employer Retirement Savings Contribution, along with financial‑planning support and company‑paid life and disability insurance. These elements are highlighted as part of the core U.S. package.
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Parental & Family Support — Parental leave is described as up to 26 weeks in the U.S. when combining paid non‑medical parental leave with medical recovery where applicable, with exact pay and weeks dependent on circumstances and plan elections. Family‑building support includes egg preservation, adoption, and surrogacy coverage.
Pfizer Insights
What We Do
Our purpose ensures that patients remain at the center of all we do. We live our purpose by sourcing the best science in the world; partnering with others in the healthcare system to improve access to our medicines; using digital technologies to enhance our drug discovery and development, as well as patient outcomes; and leading the conversation to advocate for pro-innovation/pro-patient policies.
Why Work With Us
We are the inventors, the problem solvers, the big thinkers — those who surmount any hurdle to deliver breakthrough medicines to the people who are counting on them the most.
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