Senior Manager, Commercial Portfolio Planning and Optimization

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New York, NY, USA
Hybrid
124K-201K Annually
Artificial Intelligence • Healthtech • Machine Learning • Natural Language Processing • Biotech • Pharmaceutical
We’re in relentless pursuit of breakthroughs that change patients’ lives.
The Role
ROLE SUMMARY:
This role will be responsible for development, management, and ongoing maintenance of all data, reporting, analytic tools, platforms and databases for all Commercial Portfolio Management activities and some within the Global Marketing Team, while also leading related initiatives.
Additionally, the role will be managing the day-to-day project management and operational effectiveness needs of the Portfolio Planning and Optimization (PPO) lead and key PPO global commercial platform initiatives.
Lastly, it will involve working across a broad, cross-functional organization, including the Demand/Supply Alignment (DSA) Team, Portfolio Network Planning, Competitor Supply Intelligence, Commercial Assessments & Capabilities Team, Portfolio Optimization & Simplification Team, Commercial, Manufacturing, Finance, Business Analytics, Business Technology, Global Marketing, and other departments within Pfizer
ROLE RESPONSIBILITIES:
Portfolio Planning & Optimization (PPO) Project Management / Operations Support:
  • Develop and manage PPO MS Teams, SharePoint, and other collaboration tools
  • Facilitate PPO team cross-projects integration to maintain sustainable data systems and update processes
  • Drive, implement and maintain continuous improvement by identifying, developing, and maintaining new capabilities that enhance efficiency and maximize the business's competitive advantage.
  • Provide thought partnership in building and standardizing commercial reporting eco-system
  • Identify and drive technology efficiencies across CPM technical tools

Portfolio Optimization and Simplification:
  • Project manage activities with CPM, BAI, Digital, Manufacturing, Finance, Business Analytics, Business Technology, Global Marketing, and other departments within Pfizer to develop, implement, and maintain data, reporting dashboards, metrics, tools, and analytics, ensuring data integrity synthesize and communicate the status and progress of key initiatives
  • Manage SKU Exit "Trains Tracks" database. Update database with extracts from PGS and REG21 systems. Update records with feedback from process participants. Generate performance metrics.
  • Support portfolio analysis associated with key portfolio decisions
  • Support the annual revenue and unit alignment process for the LRVF (Long Range Volume Forecast) for the PBG portfolio in partnership with Pfizer Global Supply (PGS), Commercial and Finance
  • Support the annual process to sanitize data and pressure test long range demand and assumptions with Markets, Regions, Marketing and Finance

Other Commercial Responsibilities:
  • Leverage analytic skills to simplify complicated concepts or large dataset and develop case materials/decks
  • Support ad-hoc CPM projects on an as-needed basis

QUALIFICATIONS:
  • Bachelor's degree in Data Science, Business Management, quantitative field required
  • Advanced degree in quantitative field is preferred
  • Minimum of 6 years' experience in operations, commercial, analytics, management consulting, or related discipline within the pharmaceutical industry
  • Strong Analytical, coding skills (such as: Python, R, SQL, DAX etc.) or other contemporary programming languages
  • Advanced Tableau and Power BI skills desired
  • Excellent Microsoft Office and Database skills. Advanced MS-Excel skills required
  • Knowledge of PGS systems (SAP BI, IBP) & Finance systems/datasets (MOSAIC, OpPlan, IQVIA).
  • Excellent communication skills and stakeholder relationship skills - Must be detail orientated with the ability to navigate, understand, and leverage large data sets containing commercial, finance and manufacturing information for decision making
  • Ability to perform complex data analysis

Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
Work Location Assignment: Hybrid
Other Job Details:
Last day to apply: March 9, 2026
The annual base salary for this position ranges from $124,400.00 to $201,400.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email [email protected] . This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
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Pfizer Compensation & Benefits Highlights

  • Healthcare Strength Multiple U.S. medical plan options include telehealth, comprehensive mental‑health support, fertility/family‑building benefits, transgender‑inclusive coverage, and certain Pfizer medications at no cost. A Wellbeing Wallet and wellness resources broaden the health and wellbeing offering.
  • Retirement Support A 401(k) with company matching is paired with an additional Pfizer Retirement Savings Contribution, alongside company‑paid life and disability insurance. One‑on‑one financial planning support is provided through Fidelity.
  • Leave & Time Off Breadth Paid time off spans vacation, holidays, and personal days, with additional caregiver and medical leave. U.S. parental leave commonly includes 12 weeks paid with options for additional unpaid bonding time and a return‑to‑work transition.

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