Senior Manager - Cloud Engineering

Sorry, this job was removed at 04:17 p.m. (CST) on Thursday, Jan 08, 2026
Hiring Remotely in United States
Remote
180K-210K Annually
Artificial Intelligence • Healthtech • Biotech
Where Molecular Science Meets Artificial Intelligence – Revolutionizing Cancer Care.
The Role

At Caris, we understand that cancer is an ugly word—a word no one wants to hear, but one that connects us all. That’s why we’re not just transforming cancer care—we’re changing lives.

 

We introduced precision medicine to the world and built an industry around the idea that every patient deserves answers as unique as their DNA. Backed by cutting-edge molecular science and AI, we ask ourselves every day: “What would I do if this patient were my mom?” That question drives everything we do.

 

But our mission doesn’t stop with cancer. We're pushing the frontiers of medicine and leading a revolution in healthcare—driven by innovation, compassion, and purpose.

 

Join us in our mission to improve the human condition across multiple diseases. If you're passionate about meaningful work and want to be part of something bigger than yourself, Caris is where your impact begins.

Position Summary
The Senior Manager, Cloud Engineering is responsible for leading the strategy, delivery, and operational excellence of Caris Life Sciences’ cloud infrastructure across AWS. This role oversees Cloud team ,and ensuring secure, scalable, and reliable cloud platforms that support clinical, analytical, and enterprise workloads

The Senior Manager drives cloud modernization, Kubernetes/EKS strategy, Infrastructure as Code adoption, observability improvements, and operational automation. This leader partners closely with DevOps teams, Security, Data Engineering, Software Engineering, and Networking to deliver high-performance, cost-efficient cloud architectures aligned with SOX, HIPAA, and internal security standards.
This role requires a technical leader capable of guiding senior engineers, influencing architectural direction, and enabling cross-functional execution while also providing people leadership, capacity planning, roadmap development, and operational governance
Job Responsibilities

  • Develop and execute the cloud engineering strategy aligned with organizational goals.
  • Provide architectural oversight for AWS cloud platforms, including EKS, networking, IAM, and cloud-native security.
  • Lead large-scale cloud modernization, migration, and containerization initiatives.
  • Manage and mentor DevOps engineers
  • Establish cloud best practices, standards, and technical career development paths.
  • Oversee hiring, performance management, resource planning, and workload prioritization.
  • Ensure reliability, scalability, and performance of AWS-hosted workloads and Kubernetes/EKS platforms.
  • Oversee observability strategy, including metrics, logs, traces, and incident-response processes.
  • Provide technical leadership during major incidents and drive root-cause and corrective action plans.
  • Implement and maintain HA/DR strategies, backup standards, and resilience engineering practices.
  • Drive adoption of Infrastructure as Code frameworks.
  • Oversee CI/CD modernization, automated testing, and deployment pipeline improvements.
  • Identify and implement automation opportunities across provisioning, operations, compliance, and governance.
  • Partner with InfoSec to implement cloud security policies, guardrails, and automated compliance checks.
  • Ensure engineering practices uphold SOX, HIPAA, and internal security requirements.
  • Lead cloud security posture improvements in IAM, VPC, encryption, monitoring, and vulnerability remediation.
  • Collaborate with Application Engineering, Data Engineering, Security, and networking teams to enable cloud adoption.
  • Drive cloud cost optimization, budgeting, and vendor management with finance and leadership.
  • Ensure robust documentation, runbooks, and knowledge management across cloud and DevOps teams.

Required Qualifications

  • Bachelor’s degree in Computer Science, Information Technology, Engineering, or related field.
  • 10+ years of experience in Cloud Engineering, DevOps, Infrastructure, or SRE roles.
  • 6+ years of experience in a technical leadership or people-management role.
  • Deep expertise with AWS platform services including EKS, EC2, VPC, IAM, RDS/Aurora, Lambda, S3, Security Hub, and CloudWatch.
  • Strong understanding of Kubernetes cluster architecture, container orchestration, and cloud-native security practices.
  • Extensive hands-on experience with Infrastructure as Code (Terraform, CloudFormation, CDK).
  • Proven ability to lead CI/CD modernization and DevOps best practices.
  • Experience managing cloud networking and security alignment in partnership with InfoSec (matrix model).
  • Strong understanding of regulatory and compliance requirements such as SOX and HIPAA.
  • Exceptional communication and leadership skills, with the ability to drive consensus and influence cross-functional teams.

Preferred Qualifications

  • AWS Professional Certifications (Solutions Architect Professional, DevOps Engineer Professional).
  • Kubernetes certifications (CKA, CKAD, CKS).
  • Experience with cost-optimization strategies and FinOps practices.
  • Experience with observability platforms (DataDog, Prometheus, Grafana).
  • Experience supporting large-scale distributed systems across clinical, analytics, or regulated industries.

Physical Demands

  • Must possess the ability to sit, stand, and/or work at a computer for long periods of time.

Other

  • Job may require after-hours response to emergency issues and on-call availability as required.

Annual Hiring Range

$180,000 - $210,000

Actual compensation offer to candidate may vary from posted hiring range based upon geographic location, work experience, education, and/or skill level. The pay ratio between base pay and target incentive (if applicable) will be finalized at offer.

 

Description of Benefits

  • Highly competitive and inclusive medical, dental and vision coverage options
  • Health Savings Account for medical expenses and dependent care expenses
  • Flexible Spending Account to pay for certain out-of-pocket expenses
  • Paid time off, including: vacation, sick time and holidays
  • 401k match and Financial Planning tools
  • LTD and STD insurance coverages, as well as voluntary benefit options
  • Employee Assistance Program
  • Pet Insurance
  • Legal Assistance
  • Tuition Assistance

Conditions of Employment:  Individual must successfully complete pre-employment process, which includes criminal background check, drug screening, credit check ( applicable for certain positions) and reference verification.

This job description reflects management’s assignment of essential functions. Nothing in this job description restricts management’s right to assign or reassign duties and responsibilities to this job at any time.

 

Caris Life Sciences is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, gender, gender identity, sexual orientation, age, status as a protected veteran, among other things, or status as a qualified individual with disability.

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The Company
HQ: Irving, TX
1,700 Employees
Year Founded: 2008

What We Do

Caris Life Sciences was founded in 2008 with a simple but powerful purpose – to help improve the lives of as many people as possible. With transformative technologies informed by massive amounts of big data, we are revolutionizing healthcare to provide physicians and patients with the highest quality information about their disease – from detecting it early and determining how best to treat it, to developing the next wave of novel therapies.

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