Eikon Therapeutics is a new biopharmaceutical company employing revolutionary technology at the intersection of chemistry, engineering, computation, and biology to discover novel treatments for life-threatening diseases. Eikon’s discovery platform is built on groundbreaking innovations from its founders (Nobel Prize, 2014), culminating in the creation of microscopes which enable real time, molecular-resolution measurements of protein movement in living cells, thereby unlocking otherwise intractable classes of proteins as drug targets.
Position
We are seeking a skilled and highly motivated Senior Manager, Biostatistics to join our talented team. The successful candidate will contribute their statistical expertise and strategic thinking to the design, execution, and analysis of clinical trials and experimental studies. In collaboration with cross-functional teams, you will lead statistical efforts that facilitate evidence-based conclusions and guide our research and development initiatives.
About You
The ideal candidate for this role should possess a proven track record of designing and analyzing clinical trials and experimental studies, particularly within the biotechnology, pharmaceutical, or related industries. This candidate excels in leading interdisciplinary teams to design studies, developing statistical analysis plans, performing advanced statistical analyses, and providing guidance to team members. Their proficiency in statistical programming languages, understanding of regulatory guidelines, and excellent communication skills are essential for conveying complex statistical concepts to non-technical stakeholders. The ideal candidate also demonstrates leadership capabilities and a deep knowledge of emerging trends and best practices in biostatistics, statistical tools, and software.
What You’ll Do
• Collaborate with interdisciplinary teams to design clinical trials, experiments, and studies, ensuring appropriate statistical methodologies are employed.
• Lead the development of statistical analysis plans, including endpoints, sample size determination, randomization strategies, and statistical methodologies.
• Perform advanced statistical analyses on complex datasets, interpreting results and drawing actionable conclusions.
• Provide guidance and mentorship to biostatisticians and statistical programmers within the team.
• Contribute to regulatory submissions by providing statistical expertise and preparing relevant sections of documents.
• Stay current with emerging trends and best practices in biostatistics and their application in the biotechnology field.
• Drive the implementation and utilization of advanced statistical tools and software.
Qualifications:
- PhD or equivalent degree in statistics/biostatistics or related discipline with a minimum of 3 years of clinical research and drug development experience, or a Master's degree with a minimum of 7 years relevant work experience.
- Deep, hands-on proficiency in R within the Posit/RStudio ecosystem (R Markdown, Shiny, tidyverse).
- Substantial oncology trial experience — familiarity with standard oncology designs and endpoints (RECIST, dose-escalation/optimization designs such as BOIN, biomarker-driven subgroup work).
- Demonstrated ability to independently own the full analysis lifecycle, from raw data through exploratory analysis to finished output.
- Strong understanding of regulatory guidelines (ICH, FDA, etc.) and experience authoring statistical analysis plans and reporting via tables, listings, and figures.
- Experience with Bayesian statistics and adaptive trial designs (e.g., BOIN-type dose-escalation, dose-optimization frameworks).
- Excellent communication skills, including translating statistical findings for non-technical stakeholders.
- Demonstrated leadership capabilities, including the ability to lead and mentor a team.
- Experience contributing statistical analysis to peer-reviewed clinical publications or conference presentations (e.g., trial results manuscripts, oncology conference abstracts and posters).
At Eikon, employee compensation also includes bonus and equity compensation, in addition to several generous benefit programs, including:
- 401k plan with company matching
- Medical (premiums covered by Eikon at 95%), dental and vision insurance (premiums covered by Eikon at 100%)
- Mental health and wellness benefits
- Weeklong summer and winter holiday shutdowns
- Generous paid time off and holiday policies
- Life/AD&D Insurance (premiums covered by Eikon at 100%) and optional supplemental employee-paid life/AD&D policies
- Enhanced parental leave benefit
- Daily subsidized lunch program when on-site
The expected salary range for this role is $170,000 to $204,750 depending on skills, competency, and the market demand for your expertise.
Eikon is proud to be an equal opportunity employer and will consider all qualified applicants for employment.
We are currently not accepting any new third-party agencies or firms at this time. Please do not forward unsolicited agency resumes to our website, employees or Human Resources. Eikon Therapeutics will not pay fees to any third-party agency or firm associated with unsolicited resumes.
Skills Required
- PhD in statistics/biostatistics or related with minimum 3 years clinical research and drug development experience OR Master’s with minimum 7 years relevant experience.
- Deep, hands-on proficiency in R within the Posit/RStudio ecosystem (R Markdown, Shiny, tidyverse).
- Substantial oncology trial experience, including familiarity with RECIST, dose-escalation/optimization designs (e.g., BOIN), and biomarker-driven subgroup analyses.
- Demonstrated ability to independently own the full analysis lifecycle from raw data through exploratory analysis to finished outputs.
- Strong understanding of regulatory guidelines (ICH, FDA) and experience authoring statistical analysis plans and reporting via tables, listings, and figures.
- Experience with Bayesian statistics and adaptive trial designs (e.g., BOIN-type dose-escalation and dose-optimization frameworks).
- Excellent communication skills, including translating statistical findings for non-technical stakeholders.
- Demonstrated leadership capabilities, including the ability to lead and mentor a team.
- Experience contributing statistical analysis to peer-reviewed clinical publications or conference presentations.
What We Do
Eikon Therapeutics is a new biopharmaceutical company employing revolutionary technology at the interface of biology, engineering and chemistry to discover novel treatments for life-threatening diseases. Eikon’s discovery platform is built on groundbreaking innovations from its founders (Nobel Prize, 2014), culminating in the creation of microscopes which enable real time, molecular-resolution measurements of protein movement in living cells. By directly measuring the effects of chemical compounds on the behavior of protein molecules in a live cellular environment, Eikon’s landmark assays facilitate the highly sensitive identification of compound-protein interactions that could not be identified through traditional assays, thereby unlocking otherwise intractable classes of proteins as drug targets. Furthermore, the ability to directly visualize protein mechanisms in disease coupled with the extraordinarily high-powered high-content data sets generated by Eikon’s drug-screening technology enable an unprecedented opportunity to quantitatively explore novel biology in the living cell. These insights facilitate creation and application of data-driven hypotheses to the discovery of life-saving therapies. Eikon is seeking adventurous, passionate and creative team members eager to apply their talents to empower interdisciplinary scientific exploration, inaugurate a radical drug-discovery paradigm, and ultimately create novel medicines. To learn more about open positions, please visit: https://eikontx.com/team#positions
