The Role
The Senior Manager/Associate Director will oversee early-stage drug development, coordinate cross-functional activities, maintain timelines, and facilitate communication between teams and leadership.
Summary Generated by Built In
Senior Manager/Associate Director, Program Management
Tenvie Therapeutics is developing precision‑engineered small molecule therapies to address core drivers of neurological and peripheral diseases: neuroinflammation and cellular dysfunction. Leveraging its proprietary product engine, Tenvie has the unique ability to advance both fully CNS‑penetrant and peripherally restricted products across a broad portfolio. Tenvie’s most advanced program, TNV262, a fully CNS-penetrant NLRP3 inhibitor, is in Phase 1 clinical development for cardiometabolic indications, including obesity and cardiovascular disease, as well as multiple sclerosis. In parallel, Tenvie is advancing TNV108, a peripherally restricted SARM1 allosteric inhibitor targeting peripheral neuropathies, through preclinical development. Tenvie’s clinical pipeline is complemented by discovery-stage programs across a range of related indications.
Tenvie Therapeutics is seeking a highly motivated, organized, and scientifically grounded individual to join our team as a critical cross-functional “integrator”. This role is ideal for candidates with a strong scientific background who have worked cross-functionally in a research or development environment and are eager to take on a more program-oriented leadership role. The ideal candidate will have a strong background in early-stage drug development and will help coordinate activities across multiple functions (biology, chemistry, translational sciences, regulatory, clinical, etc.), ensuring alignment, clarity of goals, and efficient execution of early development strategies. We are seeking a general athlete skillset with agility to learn on the run, build strong relationships across functions, and drive program success. This position reports to the Vice President of Program and Portfolio Management.
JOB RESPONSIBILITIES:
- Partner with program leads to plan, track, and drive the progress of early-stage drug development programs
- Facilitate cross-functional collaboration across research, preclinical, and development teams
- Develop and maintain integrated program timelines, identifying risks, dependencies, and critical path activities
- Ensure clear communication of program status, key milestones, and risks to internal stakeholders and leadership
- Support decision making by organizing data, preparing summaries, and coordinating review meetings
- Drive operational excellence by implementing structured processes, documentation practices, and meeting cadences
- Identify potential bottlenecks and proactively propose solutions to keep programs on track
- Coordinate with external collaborators, CROs, and partners as needed
- Help ensure alignment between scientific objectives and development plans
QUALIFICATIONS:
- Preferred advanced degree (Ph.D., MBA, or equivalent) in biotechnology, life sciences, business administration, or related field
- Minimum of 3-5 years of experience in biotechnology or life sciences
- Familiarity with the drug development process, particularly early-stage/preclinical development
- Demonstrated experience working across multiple functions
- Strong organizational skills with the ability to manage multiple workstreams simultaneously
- Ability to synthesize complex scientific information in clear, actionable plans
- Experience supporting or contributing to program or project planning
- Excellent communication skills, both written and verbal
- Detail-oriented, methodical, and proactive in identifying and solving problems
- Comfortable operating in a fast-paced, evolving environment
- Experience contributing to IND-enabling activities
- Exposure to regulatory interactions or documentation
- Proficiency in project management software
- $185,000-215,000 annual base salary
Tenvie is proud to be an Equal Opportunity Employer. Our goal is to have a diverse workforce. We do not discriminate on the basis of race, age, color, religion, national origin, gender, sexual orientation, gender identity or expression, veteran status or disability or any other status protected under federal, state or local law. All employment is decided on the basis of qualifications, merit and business need.
Top Skills
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The Company
What We Do
Tenvie is a biotechnology company committed to engineering small molecules that transform the treatment of neurological diseases. The company’s foundation is purpose-built with a diverse portfolio of small molecules and a proven team of CNS drug developers to rapidly deliver multiple clinical assets. Tenvie is advancing a pipeline of therapeutics focused on treating neurological, cardiometabolic, and ophthalmic diseases. Its portfolio of wholly owned, highly brain-penetrant, and precision-designed peripherally restricted small molecules address three key drivers of disease: resolving inflammation, rescuing metabolic dysfunction, and restoring lysosomal function.







