Senior Logistics Coordinator (Maternity cover - 12 month FTC)

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Cambridge, Cambridgeshire, England, GBR
In-Office
Biotech
The Role
Company Description

Bicycle Therapeutics is a clinical-stage pharmaceutical company developing a novel class of medicines, referred to as Bicycle® molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry. This constraint facilitates target binding with high affinity and selectivity, making Bicycle molecules attractive candidates for drug development. The company is evaluating zelenectide pevedotin (formerly BT8009), a Bicycle® Drug Conjugate (BDC®) targeting Nectin-4, a well-validated tumor antigen; BT5528, a BDC molecule targeting EphA2, a historically undruggable target; and BT7480, a Bicycle Tumor-Targeted Immune Cell Agonist® (Bicycle TICA®) targeting Nectin-4 and agonizing CD137, in company-sponsored clinical trials. Additionally, the company is developing Bicycle® Radioconjugates (BRC®) for radiopharmaceutical use and, through various partnerships, is exploring the use of Bicycle® technology to develop therapies for diseases beyond oncology.

Bicycle Therapeutics is headquartered in Cambridge, UK, with many key functions and members of its leadership team located in Lexington, Massachusetts, USA. For more information, visit bicycletherapeutics.com

Culture is key and all Bicycle employees actively embrace and role model our company values: 

  • We are Adventurous. We believe it’s the way to deliver extraordinary results for our patients.   
  • We are Dedicated to our Mission. You can’t change the world if you don’t have determination. 
  • We are One Team. We only succeed when we work together.  

Job Description

Based in our purpose-built facility at Granta Park, the role of the Senior Logistics Coordinator is to drive the operational effectiveness for our global shipping and receiving of goods, maintaining the correct processes from a regulatory perspective, whilst ensuring cost efficiency and performance for the company. This role will build and maintain excellent stakeholder relationships across the company, key external contractors and other third parties, to ensure the timely, efficient and compliant supply chain movements to and from our Portway site and third-party collaborators.

This highly visible role is essential for ensuring a dynamic and adaptable service, that reflects Bicycle’s global ambitions and values. In the pursuit of being the world-class leader in solid tumor medicines, it is key we deliver functions that enable and support our talent and our science.

Specifically, this role will strengthen the experience and knowledge of the Laboratories and Facilities team, reaching out across the organisation to collaborate with diverse areas such as Research and Innovation, Chemistry, Manufacturing, and Controls (CMC) and other internal stakeholders, to deliver the future plans for company growth and Bicycle’s corporate ambitions.

We also aspire to be a leading biotech in the Environment, Health and Safety area, and this role will play a key part working with senior leadership and employees to plan and embed best practice in this sphere.

You will be an excellent communicator, able to build strong relationships, have meaningful interactions with your stakeholders, and have experience of working in a dynamic and fast-paced environment.

  • Effective day to day management and performance of logistics throughout the company pipeline, liaising with couriers, internal clients and other third parties, ensuring compliance with applicable laws, regulations and GxP standards.
  • Prepare documentation and package shipments for our Research & Innovation teams, both domestic and international, ensuring compliance with all relevant legislation, dangerous goods transport regulations (air/road/sea) and H&S standards.
  • Liaise with regulatory agents, customs brokers and other parties to resolve complex queries and blockers for the delivery and import of global shipments.
  • Assist management with metrics and KPI information to assess operational and financial performance and advise on future business requirements.
  • Create, maintain and update relevant logistics documentation, including SOPs and training documentation, in support of service delivery, compliance and staff training.
  • Represent Logistics in local and company-wide meetings, including those involving Environmental, Social and Governance (ESG), Health and Safety, facilities strategy meetings and project meetings requiring specific logistics support.
  • Lead continuous improvement initiatives and maintain personal development by keeping up to date with the latest regulations, best practices and perform root cause analysis on logistics issues.
  • Raise and approve purchase orders, working with Finance to deal with invoices and queries.
  • Create and maintain clear and auditable processes for correct receipting and shipping of goods, including hazardous materials and biological samples in coordination with scientific teams and the Laboratory Support team.
  • Assist with the day-to-day upkeep of stocks in inventory stores to ensure continual support of essential science and business practices.
  • Ensure maintenance and cleanliness of the spaces used by Logistics and stores.

Performing other occasional tasks fitting this grade and the skill set of the individual may also be required by this role, including backing up for peers during holidays / absence. 

Qualifications

Essential:  

  • Substantial practical and technical knowledge and experience of logistics and shipping within a scientific environment.
  • Ability to convey complex technical information in a concise, straightforward manner to non-specialists, to advise on best practice and to produce buy-in for projects and changes.
  • Experience of logistics and supply chains in relation to manufacturing pharmaceuticals (e.g. CMC) or hazardous goods.
  • Experience of managing internal stakeholders, as well as third-party contractors, couriers, inspection agents, and receivers/shippers.
  • Evidence of recent certification in the carriage of dangerous goods e.g. IATA certified.
  • Experience in project management and leading process improvement projects.
  • Experience of training employees in logistics processes.
  • Able to work unsupervised and on own initiative, but with a strong team and service ethic.
  • Good competency levels in standard business software packages, including MS Teams, Excel, Word and bespoke platforms such as Oracle based programs.

Desirable:  

  • Certification of The Carriage of Radioactive Material by Air
  • Previous experience as a Dangerous Goods Safety Adviser (DGSA).
  • Previous involvement in “Green”/sustainability initiatives within the Logistics area.

Additional Information

  • State-of-the-art campus environment with on campus restaurant and Montessori nursery
  • Flexible working environment
  • Competitive reward including annual company bonus 
  • Employee recognition schemes
  • 28 days annual leave in addition to bank holidays + option to buy up to 5 additional days annually
  • Employer contribution to pension (employee does not have to contribute) 
  • Life assurance cover 4x basic salary 
  • Private Medical Insurance, including optical and dental cover 
  • Enhanced parental leave policies
  • Group income protection
  • Employee assistance program
  • Health Cash Plan
  • Access to company subsidized gym membership
  • Eligibility for an option grant to subscribe to shares in Bicycle Therapeutics plc. 
  • Cycle to work scheme 

Bicycle Therapeutics is committed to building a diverse workforce that is representative of the communities we serve. We recognize that diverse and inclusive teams build a stronger and more innovative company. Therefore, all qualified applicants will be considered for employment, and we do not discriminate on the basis of race, religion, colour, gender, sexual orientation, age, disability status, marital status, or veteran status.

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The Company
HQ: Cambridge
209 Employees
Year Founded: 2009

What We Do

We are Bicycle Therapeutics, a clinical-stage biopharmaceutical company. We didn’t wait for the next advance against cancer. We created it. Based on groundbreaking work conceived in the laboratory of Sir Greg Winter with the help of Professor Christian Heinis, we are pioneering the development of bicyclic peptides, or Bicycles® – a novel class of versatile, chemically synthesized medicines. Bicycles are fully synthetic short peptides constrained to form two loops which stabilize their structural geometry. This constraint is designed to confer high affinity and selectivity, and the relatively large surface area presented by the molecule allows targets to be drugged that have historically been intractable to non-biological approaches. Bicycles represent a unique therapeutic class, combining the pharmacological properties normally associated with a biologic with the manufacturing and pharmacokinetic advantages of a small molecule, yet with no signs of immunogenicity observed to date. Bicycles can be used as Bicycle conjugates to deliver toxin payloads and to precisely target local immune activation within tumors and as Bicycle T-cell modulators, which activate cytotoxic T-cells while circumventing the limitations of antibody and biologic therapies and better enabling combination therapy. Our lead product candidate, BT1718, is a Bicycle toxin conjugate currently being investigated in a Phase I/IIa open label dose escalation and expansion clinical trial sponsored by Cancer Research UK. BT1718 targets Membrane Type 1 Matrix Metalloproteinase (MT1-MMP), also known as MMP-14, which is highly expressed in many solid tumors. Our strategic collaborations are based on the ability of Bicycles to address a wide variety of targets. Through collaborations with AstraZeneca, Oxurion, Innovate UK and the Dementia Discovery Fund, we work with companies that have deep therapeutic expertise outside of oncology to enable us to more efficiently develop novel medicines for patients.

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