Jobs at Bicycle Therapeutics

Provide strategic and technical leadership for biostatistics across Bicycle's clinical portfolio. Lead and mentor a team, shape program-level statistical strategy, oversee study-level analyses and vendor work, apply advanced methods and simulations, author/approve key statistical documents, and represent biostatistics in regulatory interactions to support oncology clinical development.

Lead and mentor the biostatistics team to define statistical strategy across clinical development programs (oncology focus). Provide senior oversight of study design, analysis, simulation/modelling, regulatory interactions, SAPs/protocols, vendor work, and translate complex data into actionable insights to support program decisions and regulatory submissions.

Lead global procurement for a clinical-stage biopharma, standardizing sourcing processes, negotiating CRO/CDMO and R&D contracts, implementing procurement systems, driving cost-efficiency, supplier governance, and mentoring a procurement team while partnering with Clinical, R&D, Legal, IT, and Finance.

Lead and provide strategic, technical, and operational oversight for statistical programming across clinical development. Ensure CDISC-compliant deliverables (SDTM/ADaM), inspection-ready submissions, vendor/CRO governance, process improvement, and team leadership to support clinical trials and regulatory submissions.

Lead and provide strategic and technical oversight of statistical programming for clinical programs. Ensure CDISC-compliant SDTM/ADaM datasets, regulatory submission readiness, SOPs, vendor/CRO governance, and mentor a high-performing programming team to support clinical trials and submissions.

Lead operational coordination of a cross-functional therapeutic portfolio bridging Research & Innovation and Clinical. Maintain integrated master timelines and Gantt charts, run meeting governance, track risks and interdependencies, manage dashboards and repositories, support publications, liaise with internal teams and external partners, and drive timely execution toward IND/CTA filings and clinical milestones.