The Senior IT Systems Engineer – AI Tools Operations and Enablement / Change Management role is responsible for stable, scalable day-to-day operations of enterprise AI services while driving broad adoption across Mayo Clinic. This position combines platform operations, support model maturity, and change leadership to ensure AI tools are reliable, understandable, and useful in real-world workflows.
At a high level, this role leads issue triage and runbook-based operations, supports FinOps and usage optimization, and serves as a product-owner-style partner for enablement in adjacent platforms and business teams. The ideal candidate brings strong ITSM and operational analytics experience, excellent cross-functional communication, and preferred strength in change management, service governance, and enterprise AI rollout execution.
Under general supervision and guidance, the Senior IT Systems Engineer is responsible for the maintenance and support of moderately complex systems software and hardware computer systems at multiple Mayo Clinic sites. Actively monitor and respond to technical hardware and software problems utilizing hardware and software testing tools and techniques as well as assist in managing overall system capacity. May Interface with vendor support service groups or other external support teams to ensure proper escalation during outages or periods of degraded system performance. Expected to contribute to the selection, implementation, and maintenance of custom system software, and/or the installation and maintenance of purchased systems software, plus the configuration and support of hardware systems across Mayo Clinic. May also be asked to evaluate new products/technologies to determine impact on existing system configurations; assist with cost/benefit analysis, and feasibility studies; and assist in preparation and presentation of proposals that consider alternatives and business case gains needed for comprehensive institutional consideration. Required to produce and maintain documentation such as systems requirements, designs, resource inventories and plans as requested by the work unit leadership. Works effectively across departmental organizations gaining consensus of stakeholders. Work will be reviewed for quality, timeliness, and adequacy at predetermined milestones. Develops and maintains effective relationships with the I.T. technical staff and management across all Mayo sites in the support of multiple projects simultaneously. May be asked to perform consulting tasks or act as an information resource and/or mentor both internally and externally to the work unit. Consistently demonstrates the ability to take responsibility and accountability for managing work with little or no direct supervision. Demonstrated ability to multi-task and prioritize issues appropriately. Must have demonstrated the ability to interact effectively with a variety of personnel at multiple sites. Candidates must demonstrate proficient verbal and written communication skills using English. Occasional weekends and evening coverage will be required. Participation in 24 x 7 on-call rotation also required. Must be able to see and hear within normally acceptable standards.
This is a hybrid position and incumbent must live within 100 miles of a Mayo Clinic campus.
Mayo Clinic will not sponsor or transfer visas for this position including F1 OPT STEM.
This position requires a Bachelor’s degree plus 3 years of demonstrated technical experience or an Associate
degree plus 5 years of demonstrated technical experience. A high school diploma and 7 years of
demonstrated IT technical experience focused on managing operating systems, including configuration,
internals, and maintenance processes in a large, complex organization like Mayo Clinic may be considered in
lieu of the degree.Experience working in healthcare technology. Bachelor’s degree in computer science, information systems, engineering or related field; Master’s degree in a relevant technical discipline helpful. MCSE, CCNA, or other IT related certifications. Qualified candidates should have demonstrated experience in managing operating systems, including configuration, internals, and maintenance processes. Qualified candidates should have knowledge of system design principles, software development methodologies, project management methodologies, and some computer programming and/or system support experience. Experience managing both custom developed and vendor-supplied applications helpful. Advanced knowledge of multiple operating systems, including configuration, internals, and maintenance processes. A working knowledge of the following is preferred: Client/Server application architecture, Clustering, VB and scripting tools; MS SQL Server, Oracle, My SQL, DB2 or Sybase; Web Architecture including HTML, JavaScript, Active Server Pages (ASP), PHP; Network topologies and protocols e.g. IEEE 802.3, 802.11a/b/g, 802.1x, TCP/IP; SAN, NAS, virtualized storage environments. Experience in system hardware design, ordering, configuration, testing and implementation of large projects. Proficient verbal and written communication skills using English.
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
- Medical: Multiple plan options.
- Dental: Delta Dental or reimbursement account for flexible coverage.
- Vision: Affordable plan with national network.
- Pre-Tax Savings: HSA and FSAs for eligible expenses.
- Retirement: Competitive retirement package to secure your future.
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.
Skills Required
- Bachelor's degree plus 3 years technical experience OR Associate degree plus 5 years OR high school diploma plus 7 years in IT (degree alternative allowed)
- Demonstrated experience managing operating systems including configuration, internals, and maintenance processes
- Experience working in healthcare technology or large, complex healthcare organization
- Participation in 24x7 on-call rotation; occasional weekends and evening coverage
- Live within 100 miles of a Mayo Clinic campus (hybrid position)
- Proficient verbal and written communication skills in English
- Ability to see and hear within normally acceptable standards
- Experience with system capacity management, vendor support escalation, and runbook-based operations
- Knowledge of system design principles, software development and project management methodologies, and some programming or system support experience
- Master's degree in relevant technical discipline
- MCSE, CCNA, or other IT-related certifications
- Working knowledge of Client/Server architecture, Clustering, VB and scripting tools
- Working knowledge of databases: MS SQL Server, Oracle, MySQL, DB2, Sybase
- Working knowledge of web technologies: HTML, JavaScript, Active Server Pages (ASP), PHP
- Working knowledge of network topologies and protocols (IEEE 802.3, 802.11a/b/g, 802.1x, TCP/IP)
- Experience with SAN, NAS, and virtualized storage environments
- Experience managing both custom-developed and vendor-supplied applications
- Experience in system hardware design, ordering, configuration, testing and implementation of large projects
- Strength in change management, service governance, enterprise AI rollout execution, ITSM, and operational analytics
Mayo Clinic Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Mayo Clinic and has not been reviewed or approved by Mayo Clinic.
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Retirement Support — A no-cost pension plus an employer-matched 403(b)/401(k) is positioned as a standout differentiator, offering strong long-term financial security. Feedback suggests this retirement combination elevates overall total rewards even when base pay is moderate.
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Healthcare Strength — Expanded medical networks, enhanced fertility coverage, and employer absorption of a plan year’s premium increases point to robust healthcare offerings. Feedback suggests annual updates maintain breadth and competitiveness of coverage.
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Parental & Family Support — Adoption assistance, dependent scholarships, child and elder-care resources, and EAP services provide meaningful family-oriented support. Feedback suggests these programs add tangible value beyond salary alone.
Mayo Clinic Insights
What We Do
Mayo Clinic is the first and largest integrated, not-for-profit medical group practice in the world. Doctors from every medical specialty work together to care for patients, joined by common systems and a philosophy of "the needs of the patient come first." More than 3,800 physicians and scientists and 50,900 allied health staff work at Mayo Clinic, which has sites in Rochester, Minn., Jacksonville, Fla., and Scottsdale/Phoenix, Ariz. Mayo Clinic also serves over 70 communities through Mayo Clinic Health System with locations in MN, IA, and WI. Collectively, these locations care for more than 1 million people each year.






