Senior HPC Engineer (High Performance Computing)

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Internal Title: Sr Product Engineer

Position Summary:                    

The High Performance Computing (HPC) Engineer is responsible for ensuring the Linux-based computer used in Illumina Sequencing Platforms meeting all the functionality, security and robustness requirements. This role requires deep understanding of modern HPC architecture with the ability to optimize / finetune system performance, with benchmarking to identify system bottleneck.

The role involves in testing and evaluating HPC memory, CPU and network performance, with analysis of HPC Workload, Job Scheduling and CPU profiling. This position supports both New Product Introduction (NPI) and on-market activities within Instrument Operations and serves as a key interface with product development teams in Singapore and the US. This role collaborates cross-functionally to drive product and process enhancements, cost optimization, and operational excellence, enabling smooth transition from design to production, and sustaining high-performance standards throughout the product lifecycle.

Position Responsibilities:

• Engage early with the development team to understand HPC system level design and interactions with different functional components such as EE, Software/Firmware, Operating System, FPGA

• Diagnose HPC low-level performance bottlenecks across CPU, RAM, storage, networking and peripheral drivers.

• Collaborate with software, hardware, and systems engineering teams to qualify  new software, hardware and operating workflow for the HPC.

• Evaluate hardware components including CPUs, memory, storage, networking, and peripheral devices for platform continuity and develop sustainable solutions

• Established work instruction of HPC integration workflow, test procedure and diagnostic workflows for engineering and manufacturing use.

• Conduct comprehensive root-cause investigations for complex production issues using structured problem-solving methodologies (FMEA, DOE, and statistical analysis).

• Complete Non-conformance Records based on investigation outcomes and drive the release of instruments back into production.

• Plan and execute engineering studies to support experiments and data collection efforts.

• Participate in continuous improvement initiatives and operational excellence programs.

• Write and update work instructions as needed to improve test procedures.

Listed responsibilities are an essential, but not exhaustive list, of the usual duties associated with the position. Changes to individual responsibilities may occur due to business needs.

Position Requirements:

• Typically requires a minimum of 5 years of related experience with a Bachelor’s degree in Computing; or 3 years and a Master’s degree; or a PhD without experience; or equivalent work experience.
• Experience in Linux High Performance Computing systems (RHEL/Oracle/CentOS) in enterprise environments
• Experience in analysing HPC workload and scheduling system eg. Slurm, RunAI, Profiling etc.
• Experience in troubleshooting low-level performance bottlenecks across compute, storage, and networking layers
• Deep understanding of compute system tuning for memory, CPU, and network performance
• Good understanding of CPU architecture across Intel, AMD, and ARM with multi-threading operating system.
• Knowledge of TCP, UDP, RDMA, and server/network interface.
• Knowledge of modern memory technologies such as DDR4/DDR5, DIMM, LPDDR
• Experience with scripting languages, such as Python, Perl, or Bash to extract debug information from embedded systems and high-performing compute system
• Excellent team player, interpersonal and communication skills.
• Willing to travel to US for extended periods to learn the technology and collaborate with US design teams.
• Solid working knowledge of GDP, ISO & cGMP practices.
• Experience with FDA regulated medical device product development is preferred.
• Experience in life science–related projects or internships is advantageous; exposure to medical device environments is preferred.

All listed requirements are deemed as essential functions to this position; however, business conditions may require reasonable accommodations for additional task and responsibilities.

We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact [email protected]. To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf. The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants.